This article was recently mentioned in the Metro Times Detroit
Most recent update from Dennis Hill (2.28.13):
- My progress is good. Asked my doctor the meaning of my last three PSAs. He said: The PSA has not risen over 2.4 in nine months, we can presume the cancer is in remission. Music to my ears. Cannabinoid extract wins again. Huzzah!
Previous update (12.8.12):
- After six months using cannabis extract, a prostate biopsy confirmed the cancer was gone, in February 2010. Twenty months later, biopsy showed cancer had returned. I have reinstated cannabis extract and PSA is declining. I expect the cancer to be gone soon, just as it did previously.
On the need to decarboxylate medicine:
- “My co-op hash oil had not been decarboxylated. THCA does not fit the CB-1 receptor that is required to send seramide to the work of apoptosis.” (This is why the cancer made a reappearance)
Summary:
-
Get Rick Simpson formula oil; including the important decarboxylation step to convert THCA to THC.
- If possible, use 1:1 THC:CBD, as THC kills the cancer, CBD kills the cancer’s ability to metastasize.
- Take as much as possible; the way to kill cancer is to hit it very hard. Start very small to acclimate to the oil properties, then keep increasing the dose as tolerable.
- Take a large dose before bed, then a lighter dose during the day, to keep the pressure on the cancer.
This is how I managed my prostate cancer to have a successful resolution. ~ Dennis Hill (4.11.13)
~~~
A condensed version of the two videos to follow:
- Read Dennis Hill’s Curing Cancer With Cannabis Extract: a Journal
- Learn to make Cannabis Oil
- Notes: Cannabis and Marijuana oil/extract are terms used interchangeably to refer to Rick Simpson’s “Hemp Oil” (“RSO”). In Canada, where Rick is from, Hemp refers to cannabis. In the US, Hemp refers to the non-THC bearing plant used for textiles etc.; “Hemp Seed Oil” is sold legally, but is not the same as Rick’s high-THC “Hemp Oil”.
From Cannabis Nation Radio Biochemist Dennis Hill graduated from the University of Houston and did his Graduate Work at Baylor Medical School. Dennis worked as a Cancer Researcher at the MD Anderson Cancer Center in Houston. When Dennis was diagnosed with advanced stage prostate cancer, which had metastasized to other parts of his body, he started researching. Since Dennis has a family history of prostate cancer, and he often witnessed ineffective results while working in cancer research, he felt a new approach was in order.
After researching possible alternatives Dennis ran across information about Rick Simpson using cannabis concentrate, which is an extract of the essential oil which is extracted from marijuana and contains cannabinoids. Simpson was using the oil to treat a wide variety of illness, including cancer. The more Dennis researched, the more he understood how cannabis worked on cancer. He has included 2 papers for the review of anyone interested that go into the science of how cannabis kills cancer. He was determined to give it a try, and decided to tell his doctor that he would be using cannabis concentrate alone for his treatment. He did not want to risk more damage to his body from chemo, so he chose to start the cannabis oil regime without any other treatment.
Dennis is educated, with a sound background in science, and a background in the cancer industry. He stated that the Cannabis Oil killed the cancer, and he is now cancer free. He never underwent any of the standard treatment ie chemo, or radiation. He maintained a healthy diet, and exercise as part of his healing and after care. Dennis worked two jobs while he was treating himself, and never experienced any of the side effects typically associated with standard cancer treatments. He administered 1 tiny dose of the cannabis oil in the AM, and 1 tiny dose of the cannabis oil in the pm, just as Rick Simpson suggests.
Here, Dennis Hill explains the inner workings of cancer death-by-Cannabinoids:
Cannabinoids and cancer
Cancer-specific Cytotoxicity of Cannabinoids
By Dennis Hill (reprinted with permission)
First let’s look at what keeps cancer cells alive, then we will come back and examine how the cannabinoids CBD (cannabidiol) and THC (tetrahydrocannabinol) unravels cancer’s aliveness.
In every cell there is a family of interconvertible sphingolipids that specifically manage the life and death of that cell. This profile of factors is called the “Sphingolipid Rheostat.” If ceramide (a signaling metabolite of sphingosine-1-phosphate) is high, then cell death (apoptosis) is imminent. If ceramide is low, the cell will be strong in its vitality.
Very simply, when THC connects to the CB1 or CB2 cannabinoid receptor site on the cancer cell, it causes an increase in ceramide synthesis which drives cell death. A normal healthy cell does not produce ceramide in the presence of THC, thus is not affected by the cannabinoid.
The cancer cell dies, not because of cytotoxic chemicals, but because of a tiny little shift in the mitochondria. Within most cells there is a cell nucleus, numerous mitochondria (hundreds to thousands), and various other organelles in the cytoplasm. The purpose of the mitochondria is to produce energy (ATP) for cell use. As ceramide starts to accumulate, turning up the Sphingolipid Rheostat, it increases the mitochondrial membrane pore permeability to cytochrome c, a critical protein in energy synthesis. Cytochrome c is pushed out of the mitochondria, killing the source of energy for the cell.
Ceramide also causes genotoxic stress in the cancer cell nucleus generating a protein called p53, whose job it is to disrupt calcium metabolism in the mitochondria. If this weren’t enough, ceramide disrupts the cellular lysosome, the cell’s digestive system that provides nutrients for all cell functions. Ceramide, and other sphingolipids, actively inhibit pro-survival pathways in the cell leaving no possibility at all of cancer cell survival.
The key to this process is the accumulation of ceramide in the system. This means taking therapeutic amounts of cannabinoid extract, steadily, over a period of time, keeping metabolic pressure on this cancer cell death pathway.
How did this pathway come to be? Why is it that the body can take a simple plant enzyme and use it for healing in many different physiological systems? This endocannabinoid system exists in all animal life, just waiting for it’s matched exocannabinoid activator.
This is interesting. Our own endocannabinoid system covers all cells and nerves; it is the messenger of information flowing between our immune system and the central nervous system (CNS). It is responsible for neuroprotection, and micro-manages the immune system. This is the primary control system that maintains homeostasis; our well being.
Just out of curiosity, how does the work get done at the cellular level, and where does the body make the endocannabinoids? Here we see that endocannabinoids have their origin in nerve cells right at the synapse. When the body is compromised through illness or injury it calls insistently to the endocannabinoid system and directs the immune system to bring healing. If these homeostatic systems are weakened, it should be no surprise that exocannabinoids perform the same function. It helps the body in the most natural way possible.
To see how this works we visualize the cannabinoid as a three dimensional molecule, where one part of the molecule is configured to fit the nerve or immune cell receptor site just like a key in a lock. There are at least two types of cannabinoid receptor sites, CB1 (CNS) and CB2 (immune). In general CB1 activates the CNS messaging system, and CB2 activates the immune system, but it’s much more complex than this. Both THC and anandamide activate both receptor sites. Other cannabinoids activate one or the other receptor sites.Among the strains of Cannabis, C. sativa tends toward the CB1 receptor, and C. indica tends toward CB2. So sativa is more neuroactive, and indica is more immunoactive. Another factor here is that sativa is dominated by THC cannabinoids, and indica is predominately CBD (cannabidiol).
It is known that THC and CBD are biomimetic to anandamide, that is, the body can use both interchangeably. Thus, when stress, injury, or illness demand more from endogenous anandamide than can be produced by the body, its mimetic exocannabinoids are activated. If the stress is transitory, then the treatment can be transitory. If the demand is sustained, such as in cancer, then treatment needs to provide sustained pressure of the modulating agent on the homeostatic systems.
Typically CBD gravitates to the densely packed CB2 receptors in the spleen, home to the body’s immune system. From there, immune cells seek out and destroy cancer cells. Interestingly, it has been shown that THC and CBD cannabinoids have the ability to kill cancer cells directly without going through immune intermediaries. THC and CBD hijack the lipoxygenase pathway to directly inhibit tumor growth. As a side note, it has been discovered that CBD inhibits anandamide reuptake. Here we see that cannabidiol helps the body preserve its own natural endocannabinoid by inhibiting the enzyme that breaks down anandamide.
In 2006, researchers in Italy showed the specifics of how Cannabidiol (CBD) kills cancer. When CBD pairs with the cancer cell receptor CB-2 it stimulates what is known as the Caspase Cascade, that kills the cancer cell. First, let’s look at the nomenclature, then to how Caspase kills cancer. Caspase in an aggregate term for all cysteine-aspartic proteases. The protease part of this term comes from prote (from protein) and -ase (destroyer). Thus the caspases break down proteins and peptides in the moribund cell. This becomes obvious when we see caspase-3 referred to as the executioner. In the pathway of apoptosis, other caspases are brought in to complete the cascade.9
Even when the cascade is done and all the cancer is gone, CBD is still at work healing the body. Its pairing at CB-2 also shuts down the Id-1 gene; a gene that allows metastatic lesions to form. Fundamentally this means that treatment with cannabinoids not only kills cancer through numerous simultaneous pathways, but prevents metastasis. What’s not to like. One researcher says this: CBD represents the first nontoxic exogenous agent that can significantly decrease Id-1 expression in metastatic carcinoma leading to the down-regulation of tumor aggressiveness.10
This brief survey touches lightly on a few essential concepts. Mostly I would like to leave you with an appreciation that nature has designed the perfect medicine that fits exactly with our own immune system of receptors and signaling metabolites to provide rapid and complete immune response for systemic integrity and metabolic homeostasis.
Bibliography
1. http://cancerres.aacrjournals.org/content/65/5/1635.abstract
Sami Sarfaraz, Farrukh Afaq, Vaqar M. Adhami, and Hasan Mukhtar + Author Affiliations. Department of Dermatology, University of Wisconsin, Madison, Wisconsin
2. http://www.ncbi.nlm.nih.gov/sites/pubmed
J Neuroimmunol. 2007 Mar;184(1-2):127-35. Epub 2006 Dec 28.
Immune control by endocannabinoids – new mechanisms of neuroprotection? Ullrich O, Merker K, Timm J, Tauber S.
Institute of Immunology, Medical Faculty, Otto-von-Guericke-University Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany. oliver.ullrich@medizine.uni-magdeburg.de
3. http://en.wikipedia.org/wiki/Endocannabinoid_system
Endocannabinoid synthesis & release.
4. http://en.wikipedia.org/wiki/Cannabinoids
Cannabinoid receptor type 1.
5. http://www3.interscience.wiley.com/journal/121381780/abstract?CRETRY=1&SRETRY=0
Journal of Neurochemistry, Volume 104 Issue 4, Pages 1091 – 1100
Published Online: 18 Aug 2008
6. http://leavesofgrass.info/info/Non-Psychoactive-Cannabinoids.pdf
Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb.
Angelo A. Izzo, Francesca Borrelli, Raffaele Capasso, Vincenzo Di Marzo, and Raphael Mechoulam. Department of Experimental Pharmacology, University of Naples Federico II, Naples, Italy. Institute of Biomolecular Chemistry, National Research Council, Pozzuoli (NA), Italy. Department of Medicinal Chemistry and Natural Products, Hebrew University Medical Faculty, Jerusalem, Israel, Endocannabinoid Research Group, Italy
7. http://sciencenews.org/view/feature/id/59872/title/Not_just_a_high
Scientists test medicinal marijuana against MS, inflammation and cancer
By Nathan Seppa June 19th, 2010; Vol.177 #13 (p. 16)
8. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1766198/
NIH Public Access:
A house divided: ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell death
Tarek A. Taha, Thomas D. Mullen, and Lina M. Obeid
Division of General Internal Medicine, Ralph H. Johnson Veterans Administration Hospital, Charleston, South Carolina 29401; and Department of Medicine, Medical University of South Carolina, Charleston, South Carolina 29425
Corresponding author: Lina M. Obeid, M.D., Department of Medicine, Medical University of South Carolina, 114 Doughty St., P.O.Box 250779, Charleston, South Carolina 29425. E-mail: obeidl@musc.edu
9. P. Massi, A. Vaccani, S. Bianchessi, B. Costa, P. Macchi, D. Parolaro
Cellular and Molecular Life Sciences CMLS
September 2006, Volume 63, Issue 17, pp 2057-2066
http://link.springer.com/article/10.1007%2Fs00018-006-6156-x?LI=true
10. Mol Cancer Ther. 2007 Nov;6(11):2921-7.
Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells.
McAllister SD, Christian RT, Horowitz MP, Garcia A, Desprez PY.
California Pacific Medical Center, Research Institute, 475 Brannan Street, San Francisco, CA 94107, USA. mcallis@cpmcri.org
http://www.ncbi.nlm.nih.gov/pubmed/18025276
The Human Endocannabinoid System Meets the Inflammatory Cytokine Cascade
By: Dennis Hill
The Endocannabinoid System (ECS) started revealing itself to researchers in the 1940s and by the late ’60s the basic structure and functionality had been laid out. Today we know the ECS is a comprehensive system of biochemical modulators that maintain homeostasis in all body systems including the central and peripheral nervous systems, all organ systems, somatic tissues, and all metabolic biochemical systems, including the immune system.
This homeostatic matrix is not a recent evolutionary twist just for humans; we Find the Endo cannabinoid System in every chordate creature for the last 500 million years. It is a fully mature biochemical technology that has maintained health and metabolic balance for most of the history of life itself.
The two major interactive systems within the ECS are (1) the cannabinoid receptors that we find on all cell surfaces and neurological junctions and (2) the endocannabinoids that hit the receptors to trigger various metabolic processes. Looking at a cannabinoid receptor distribution map we see that CB1 receptors, that are most sensitive to anandamide, are found in the brain, spinal nerves, and peripheral nerves. CB2 receptors preferred by 2-arachidonoylglycerol (2-AG) are found largely in the immune system, primarily the spleen. A mix of CB1 and CB2 receptors are found throughout the rest of the body including the skeletal system. And yes, 2-AG or CBD will grow new trabecular bone.1 It is also useful to note that both anandamide and 2-AG can activate either CB1 or CB2 receptors.
The nature of the endocannabinoids are functionally much like neurotransmitters, but structurally are eicosanoids in the family of signaling sphingolipids. These signaling cannabinoids keep track of metabolic systems all over the body. This information is shared with the nervous system and the immune system so that any imbalance is attended to. If the body is in chronic disease or emotional stress, the immune system can fall behind and lose control of compromised systems. It is here that phytocannabinoids can pitch in to support the stressed body in a return to health. The cannabis plant provides analogues of the body’s primary signaling cannabinoids. Tetrahydrocannabinol (THC) is mimetic to anandamide, and cannabidiol (CBD) is mimetic to 2-AG, and has the same affinity to CB1 and CB2 receptors; providing the body with additional support for the immune and endocannabinoid systems.
Phytocannabinoids supercharge the body’s own Endocannabinoid System by amping up the response to demand from the immune signaling system in two modes of intervention: one, of course, is in bonding with the cannabinoid receptors; the other is in regulation of innumerable physiological processes, such as cannabinoid’s powerful neuroprotective and anti-inflammatory actions, quite apart from the receptor system. It is interesting to note here that the phytocannabinoids and related endocannabinoids are functionally similar, but structurally different. As noted above, anandamide and 2-AG are eicosanoids while THC and CBD are tricyclic terpenes.
Let us look more closely at the two primary therapeutic cannabinoids, THC and CBD. The National Institutes of Health tell us that THC is the best known because of its signature psycho- tropic effect. This government report shows THC to be effective as an anti-cancer treatment, an appetite stimulant, analgesic, antiemetic, anxiolytic, and sedative.2
CBD (cannabidiol) is a metabolic sibling of THC, in that they are alike in many ways but are also different in important properties. First we see that CBD has no psychotropic effects and there are few CB2 receptors in the brain and peripheral nerves. There appears to be a broader therapeutic profile associated with CBD, which is listed here:
One of the most important health benefits of cannabinoids is their anti-inflammatory property. In this, they are strong modulators of the inflammatory cytokine cascade. Numerous disease states arise out of chronic inflammation; such as, depression, dementias including Alzheimer’s, cancer, arthritis and other autoimmune disorders, viral infection, HIV, brain injury, etc.
Inflammatory cytokines can be activated by oxidative stress and disease states. Cannabinoids, being immunomodulators interrupt the cytokine inflammatory cascade so that local inflammation does not result in tissue pathology. Thus we are spared morbid or terminal illnesses.4
If our own endocannabinoid system can maintain metabolic homeostasis and even cure serious disease, why are we plagued by illness? We know that the body produces only small amounts of anandamide and 2-AG; enough to maintain the body but not enough to overcome chronic stress, illness, injury, or malnutrition. Cannabis is the only plant we know of that produces phyto- cannabinoids that mimic our own endocannabinoids. One of the great benefits of this mimetic medicine is that cannabinoids are essentially natural to our biology and do no harm to our tissues and systems.
It is well known that most diseases of aging are inflammatory in origin, thus making cannabis the best anti-aging supplement we could take to avoid arthritis, dementia, hypertension, diabetes, osteoporosis, and cancer. This is our key to good health and long life.
Since it is such an important attribute, as well as being independent of the cannabinoid receptor system, let’s look a little deeper into the ability of cannabinoids to inhibit the inflammatory cytokine cascade. Inflammation is good for us, a little here, a little there; it brings T-cells and macrophages to infection sites. This is good. However, chronic inflammation can cause serious illness and death. How do phytocannabinoids rescue us from dreaded infirmities? When the call comes in to the immune system to send troops, the First thing to happen is that the immune system signals glial cells to produce cytokines. Once this cat is out of the bag, the process can go one of two ways.
A) Killer cells clean up the infection and all is well.
B) Cytokines can stimulate more cytokine production and cause many more cytokine receptors to awaken. Unchecked, this becomes a cytokine storm showing symptoms of swelling, redness, fatigue, and nausea; even death.
Phytocannabinoids have the ability to suppress this inflammatory cytokine cascade by inhibiting glial cell production of the cytokines interferon or interleukin. Here we see the seeds of chronic inflammation dissolved by the modulation process of cannabinoids bringing homeostasis to systems out of balance. This is a good example of how cannabinoids normalize biological processes all throughout the body and allows us to keep that glow of well-being through a long and happy lifetime. (Bibliography)
Dr Bob Melemede explains further
A comment from the Metro Times Detroit article Pot and the Big “C” (comment section)
I have been researching Rick Simpson’s claims not for almost 2 years — I am happy to report that they are 100% true! I have personally communicated with numerous people who have put their very serious cancers into remission (I do not use the word “cure” because in some cases it has not been 5 years — in some it has been well over 5 years). That research has been stultified on using this plant for cancer and many other ailments IS the crime. The REAL truth — governments had ulterior agendas and they were as malevolent as they could be … pure evil! The bible actually warned that “they” (governments) would, “in later times” try to keep the “plant of renown” away from you … they will be “hypocrites”. It has come to pass and we have to change it because what is happening now is NOT what God wanted for his “plant of renown”.
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He reports that his cancer has returned
@Sunil Aggarwal Please provide details….did “prostate cancer” return or was it another form…had the patient stopped using the Rick Simpson oil when the cancer returned. Please provide details..what was the source of your information please. Thanks
Hello Dennis
My query is, were you or have you ever been on anti-androgens during your cannabis treatment ? If you were seeing a urologist this is usually their first line of defence.
Over the course of six months of cannabinoid treatment, I had two injections of Lupron, an androgen inhibitor that does not kill cancer. ~Dennis
Is there an independant all clear or report of remission?
Pingback: Healing Cancer Using Various Alternative Therapies | Cancer Compass ~ An Alternate Route
Sepp: that picture of the new world humming bird dipping into a cannabis flower is the best cannabis picture I’ve ever seen. The humming bird is “bird supreme” and is ultra selective about what it feeds on. This smallest of birds is the king of all birds in the americas, it will drive off anything from its territory, including hawks, ravens, even falcons. Our former apple orchard, now a mega wine industry chemical waste dump, was full of them, amazing animals to observe. Ants are very attracted to flowering cannabis tops for some reason. Writing you from original cannabis culture Japan where use as medicine was ubiquitous prior to WW2. Now it is hysterical paranoia.
Local monkeys are cruising around outside my window, howling and such (macaque of Japan). I live in the country well south , one would hope, of the nuclear disaster zone.
Probably a different treatment would be just to vaporize the stuff on a regular basis, or eat the juiced raw flower tops (no psychoactive effect apparently) The distillation method with nasty chemicals requires a very large amount of flower top (legality issues, horticultural issues in terms of difficulty, risk of thefts, etc). topical applications on skin cancers are treated by concentrates, however. Simpson’s extraction method was very primitive, leaving large quantity of toxic waste to be disposed of or evaporated (not good either). Poor guy got screwed badly by authorities, et al.(Simpson)
Thanks for the gambia news, better than news about the kiddie vaccine for malaria .
Best regards Neal
Explanation:
After six months using cannabis extract, a prostate biopsy confirmed the cancer was gone, in February 2010. Twenty months later, biopsy showed cancer had returned. I have reinstated cannabis extract and PSA is declining. I expect the cancer to be gone soon, just as it did previously. ~Dennis Hill
Hi Dennis,
Thank you for this update. My understanding is that Dr. Donald Abrams’ protocol involves a daily maintenance dosage of the oil after the cancer is gone. I wonder if you were aware of that, and if you implemented this or plan to?
I knew of Dr. Abram’s maintenance protocol and tried to follow it; however I learned too late that my co-op hash oil had not been decarboxylated. THCA does not fit the CB-1 receptor that is required to send seramide to the work of apoptosis. I will not make that mistake again. After this round of cancer goes away, I will stay with the decarboxylated oil. A very important lesson I have learned.
~Dennis Hill
Thank you, Dennis – this information is simply invaluable. From my understanding, one rice-grain-sized amount of oil once or twice a day is for treating cancer, is this right? I wonder what size would be for the daily maintenance dose.
Rick says start with one rice-grain-sized amount. He also says to increase the dose as you get acclimated. I worked up to two caps in the evening, about 12 grain size. So a maintenance dose might be half or a quarter of that. Say, one cap rather than two. If decarboxylated, this should keep even cancer stem-cells down. I’ll let you know when I find out.
~Dennis
“Cap” means a gel-capsule filled with the oil, i assume. So a maintenance dose would be 1 cap filled with from 3-6 rice grains’ worth of *decarboxylated* oil per day (?)
On a side note, here are two articles regarding solvents used in R.S.oil that readers might find useful:
Rick Simpson on solvents: http://phoenixtears.ca/articles/solvent-residue-in-the-oil/
Interesting thread about using Everclear: https://www.greenpassion.org/index.php?/topic/28768-using-everclear-to-make-rick-simpsons-oil/
On a personal note, the reason i made this post, and discovered your story in the first place, is that my good friend received a diagnoses of returned cancer to her breasts. Her doctor wanted them removed within weeks.
Your story was the most profound and persuasive one that i came across in my search for information about RSO, so I put everything I found together for her. She’s a nurse, so I thought she would particularly like the science you’ve offered us.
My friend became excited about the potential of RSoil and made a batch. She took it for about two weeks, but decided she was too nervous and went ahead and had a double mastectomy.
When the doctor removed the tumor, he found that it had reverted to a pre-cancerous state in the few weeks between biopsy and surgery.
Hopefully we can get a clear protocol laid out so that fewer people have to have body parts removed (and worse). This is the reason i am asking so many questions
Thank you for your patience, and we all are wishing you the best!
Looks like you understand my situation here. But we have to remember that everyone is different in many ways. Tolerances, especially, are variable. The medical cannabis movement is very short on standards about anything, so we experiment a lot out here in the wild. That’s just the way it works, strange as it seems. Thanks for the deeply meaningful story about your friend who took the oil for two weeks. ~Dennis
Wow, am I glad to have the uncertainty about Dennis’ treatment cleared up! How did I miss it for nearly 2 weeks? “Update from Dennis Hill” should have been a headline on the weekly news summary. Now can someone get a report from Tommy Chong? I don’t troll all the cannabis blogs, but this one is the best I know of.
I believe Tommy is saying he’s 90% (or so) cancer free, he’s still using the oil but according to Simpson, he hasn’t been taking it according to instruction ( not enough). Tommy has a podcast that keeps us updated.
Okay. Where is Tommy’s podcast?
http://www.google.com/url?sa=t&source=web&cd=1&ved=0CC0QFjAA&url=https%3A%2F%2Fitunes.apple.com%2Fus%2Fpodcast%2Fthe-chong-and-chong-show%2Fid536783829&ei=Y0_XUPGGEobs2AWR0oCYBw&usg=AFQjCNFbLfKkMUyaXYFenjPS_zJXaGYkNQ
I believe it was in October that he speaks about it.
Rick Simpson’s comments were during a radio show interview, I believe it was the one with the Truther Girls http://patients4medicalmarijuana.wordpress.com/2012/05/23/rick-simpson-talks-about-marijuana-cancer-cure-with-the-truther-girls/
http://www.phoenixtears.ca
Would appreciate it if anyone could confirm whether decarboxylated oil is required in all treatments for cancer? (inc stage 4 secondary liver & bone)
The research I have seen says that the way the immune system (part of the endocannabinoid system [ECS]) naturally identifies cancer cells is through the abnormal DNA. As far as I know, all cancers have abnormal DNA. When cancer is detected, the ECS pairs anandamide to the CB-1 cell receptors which causes the cell to die. Anandamide is mimetic to THC, which also pairs with CB-1 and causes cancer cell death.
This cannot happen unless the THCA in cannabis has been decarboxlylated; as THCA does not fit the CB-1 receptor, thus no cell death.
The logic here suggests that decarboxylated cannabis extract should kill all cancers, but of course we don’t know if it is true or not until there has been clinical testing of all cancers treated with decarboxylated cannabis oil. The research suggests that it is THC at CB-1 that kills cancer, not CBD (cannabidiol) at its preferred receptor, CB-2. CBD is wonderfully therapeutic, but I haven’t yet seen demonstration of its mechanism to kill cancer. If it’s out there, somebody please show me. ~Dennis
Project CBD http://projectcbd.org/
Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells. http://www.ncbi.nlm.nih.gov/pubmed/18025276
Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis. http://www.ncbi.nlm.nih.gov/pubmed/20859676
(the above from the Daily Beast Sept 2012 http://www.thedailybeast.com/articles/2012/09/06/marijuana-fights-cancer-and-helps-manage-side-effects-researchers-find.html)
Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma. http://www.ncbi.nlm.nih.gov/pubmed/16728591
“How THC and CBD Work Together” http://pureanalytics.net/blog/2012/02/19/how-thc-and-cbd-work-together/
“Marijuana’s better known cannabinoid – delta-9 tetrahydrocannabinol, or THC – had already shown some anticancer properties in tumors, but the non-psychotropic cannabidiol had largely gone unstudied. McAllister initial research showed CBD had anticancer potential as well.” Read more: http://www.sfgate.com/health/article/Pot-compound-seen-as-tool-against-cancer-3875562.php#ixzz2GOF7CSka
CBD stops breast cancer spread http://www.dailymail.co.uk/health/article-2206056/Cannabis-compound-stop-breast-cancer-spreading.html
Dr. Sean McAllister – THC and CBD
“Researchers found that the anti-tumour effects of CBD were caused by induction of apoptosis (programmed cell death). They concluded that their data “support the further testing of cannabidiol and cannabidiol-rich extracts for the potential treatment of cancer.” http://www.cannabis-med.org/english/bulletin/ww_en_db_cannabis_artikel.php?id=220#2
The non-psychoactive cannabidiol triggers caspase activation and oxidative stress in human glioma cells http://link.springer.com/article/10.1007%2Fs00018-006-6156-x
Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas. http://www.ncbi.nlm.nih.gov/pubmed/15313899
Cannabidiol-induced apoptosis in human leukemia cells: A novel role of cannabidiol in the regulation of p22phox and Nox4 expression. http://www.ncbi.nlm.nih.gov/pubmed/16754784
“Cannabidiol Induces Activation of the Caspase Cascade through CB2. The activation of the caspase cascade is commonly associated with the induction of apoptosis. Therefore, to further investigate the mechanism of cannabidiol-induced apoptosis, we examined the activation pattern of caspases after CBD exposure. ”
http://molpharm.aspetjournals.org/content/70/3/897.long#title2
” Taken together, these data suggest that although both THC and CBD exposure can lead to the induction of apoptosis in leukemia cells, their mechanisms of action may be distinct from one another. Therefore, treatments using the combination of THC and CBD may significantly enhance the efficacy of tumor killing. To date, this approach has not been reported for the treatment of leukemia or lymphoma. However, initial studies demonstrated that the combination of CBD and THC was better tolerated than THC alone (reviewed in Russo, 2006), possibly allowing for the use of increased levels of THC without the unwanted psychoactive side effects. In fact, it was shown that CBD could antagonize some of the undesirable effects of THC, such as its psychoactive properties, by blocking conversion of THC to the more psychoactive 11-hydroxy-THC (Bornheim and Grillo, 1998). On the other hand, as shown in the current study and by other investigators examining the effects on gliomas (Massi et al., 2004), CBD alone has been shown to possess potent antitumor activity. Taken together, these studies suggest that the combination of THC and CBD may produce a powerful combination for the treatment of various cancers, including gliomas and malignancies of the immune system.”
http://molpharm.aspetjournals.org/content/70/3/897.long#title2
It is my understanding that only THCA needs to be decarboxylated; in order to fit the receptor CB-1. Cannabidiol fits the CB-2 receptor natively, so no need to cook. Basically THC is THCA with the carboxyl group (a carbon, two oxygens and a hydrogen), liberated by heating. THC fits the CB-1 receptor perfectly, causing cancer cell death, but not THCA. Receptors on the cell wall account for most of the intelligence of a cell. These receptors manage the relationship between the external environment and cell function. Very complex. The Caspase Cascade is activated by cannabidiol through the CB-2 receptor to cause apoptosis in cancer cells. This is a very complex pathway, only recently revealed. So far I see that caspases are cysteine proteases; enzymes that break down polypeptides, ultimately causing apoptosis. That’s the chemistry, but what is really happening at the CB-2 receptor? Does anyone know the pathway that wakes up when CBD hits the receptor? How does that start the cascade? I love a mystery.
~Dennis
Pingback: Prostate stage4 cancer survivor Dennis Hill fights again his recidivism with hash oil. « Cannabis-Cures-Cancer.net
What was your PSA when you were in remission and then what did it rise to that prompted the biopsy? My husband says he does not want to go through another biopsy as we are considering all of his options? Also, how did you learn about the fact that the hemp oil that you were formerly taking was not decarboxylated? What dispensary are your currently using to ensure that your oil is not decarboxylated? We live in a state that is has not legalized med mj. My husband says he is not willing to go to prison to save his prostate. Any suggestions on acquiring the purest form of hemp oil with those two caveats would be greatly appreciated.
Best of health to you!
What was your PSA when you were in remission and then what did it rise to that prompted the biopsy?….Remission PSA was 0.1; at biopsy PSA was 1.9.
what dispensary are you currently using to ensure that your hemp oil is decarbed?….I’m using a legal private co-op, everyone gives work equity, no money changes hands. I know the person who makes the oil. I know the oil is decarboxylated. I watch.
If you are looking for a dispensary, enter your zip code here:
http://legalmarijuanadispensary.com/index.php
~Dennis
HI Dennis, would appreciate any advice to someone with secondary breast cancer with multiple liver & bone metastases as well as lymphadenopathy in chest & abdomen. We have aquired two different oils without the option to test it. Have been taking it for less than two weeks. No symptoms at all from the cancer. I’m just hoping you may be able to give any advice that you may have picked up during your treatment. It would be great to know which dispensary you used (even though im not in the US). I’d hate to think it doesnt work out because we are using the wrong type of oil or doing something we shouldnt be. THANKYOU
I never ever went to a dispensary. My treatment was all home grown and processed. Here is what I have learned about cancer and cannabis: all cancers have abnormal DNA and our endocannabinoid system can heal it. To kill cancer with cannabis extract you have to hit it as hard as you can. Start small, increase doses often, take as much as you can tolerate. Cannabis extract is not harmful to the body; more is better. If you can find it, a strain of THC:CBD=1:1 is best. If you don’t like the effects of THC, use high CBD, that will do it. Both is better, though. This is as simple as I can make it. ~Dennis
Thanks Dennis. Appreciate you advice. Will keep taking it (as much as possible)
Correction: what dispensary are you currently using to ensure that your hemp oil is decarbed?
Dennis, was chatting with some medical people about this and one said that cannabis kills brain cells. I know that Rick talks about that adage from the past. Is there evidence to support that comment?
If you know so much about what Dennis is doing and Rick has said, then you’re probably smart enough to answer that question yourself instead of bothering him with it.
Also, do you anticipate being on a maintenance dose the rest of your life?
Great question about being on maintenance forever. Two ways to go here; 1) stop cannabis, get PSA every three months. 2) continue maintenance. At this point I’m inclined to continue maintenance. Cannabis is such a great support for the immune system. I’m never sick when I’m taking it. Cannabis is a modulator of wellness in all systems in the body. It’s like the best vitamin you can take to sustain optimum health. There’s no down-side to maintenance. ~Dennis
Scott, you are so right. I don’t want to bother Dennis! I was curious as to what his reponse would be. Also I wasn’t sure if the dosage of hemp oil for cancer would be considered high enough to cause damage. It’s such a shock to hear the diagnosis of cancer and then try to sort through all the conflicting information. I’m not a scientist, just a wife searching for answers for my husband who was diagnosed with cancer about a month ago.
Anon,
Sorry to be curt with you, and many thanks for your sincere explanation. In the climate of fear the government has pushed since the 1930s, it’s easy to get worried–which is exactly what they want.
The short answer, I believe, is that cannabis is most likely to protect the brain rather than harm it. After all, the feds have a patent on it for exactly that use, as a “neuroprotectant.”. They’ve been hunting for adverse effects for decades and this is what they’ve come up with, not brain damage.
Rick Simpson appears to live on mega-doses of cannabis–which he takes for brain damage from an accident–and is doing great with it under very stressful circumstances.
You might want to look at it this way: Cancer causes brain damage (or damage to any other body part it affects). Cannabis appears to stop cancer, and may promote brain healing.
Best wishes on your search,
Scott
Thank you Dennis, Scott and the Administrator for you time and help. I believe the oil is worth a try if we can find a way to get through the legal maze because we live in a state where it’s illegal. The residency requirements are “high” hurdles to get over:).
This is exactly why we fight to end prohibition!! Blessings to you ~ please keep us posted.
Thank you Scott. There are so many theories, treatments, unscrupulous practitioners/scientist etc. it’s overwhelming in knowing who or what to trust. Science, like anything else can be twisted. This forum gives some comfort, in it’s educational content, and yet for someone new to the idea of using hemp for cancer treatment and without a chem degree, it’s all a little daunting to decipher! It seems like cancer treatment is a “choose your side effects” decion.
Does anyone have any experience of taking the concentrated oil (RSO) in conjunction with chemo ? I mentioned ‘Chinese herbs’ to the oncologist (i didnt want to mention the oil) he went on to tell me about another patient taking something (he didnt say what, but i presume some type of herb) with the chemo that was “very dangerous & caused complications, esp to the liver sas the liver metabolises.. and the.elevated the chemo effect..”. Thats obviously got me very worried. It sounds like it makes sense, the oil is very concentrated, the effect is way more than just smoking a joint.
Furthermore, i hate to be negative, trying not to be but considering the circumstances, its sometimes hard not to be. But after all the research, getting the oil etc I’ve only ever seen two preclinical trials (one with a mouse and one with a petri dish) that shows the oil getting rid of cancer cells. With everybody else its always a story or a friend. I dont understand why a organisation like,say Phoenix tears doesnt start some kind of kickstarter campaign to raise the funds required where people can anonoymously upload before and after Cat scans, strain of oil, CBD & THC levels, letters from the hospital. Whether they had chemo as well. as the oil. Will this make the evidence more than just ancedotal ? Some kind of structure rather than a short testimonial or a story of a friend.
I want this oil to work, believe me I do, i think about it everyday (the life of a loved one depnds on it) but I do wonder about this whole ‘Big Pharma’ wont do it arguement. There are many countries out there without big pharma (Cuba, Iran, Bolivia, Venuzula, Argentina). Really, are we saying all these countries are tied into a Big Pharma conspiricy. Surely, say Cuba, would have researched it, proved, bottled it and exported it globally by now. They would make a mint (not everybody can grow and make it themselves, plus it would have some kind of consistency. In a similar way we buy beer rather than grow the hops and ferment it etc).
Regarding the PhoenixTears idea–are you ready to upload your medical information to the internet? Rick Simpson is practically a stateless person now that he’s challenged Canada so forcefully. He’s been raided by the Mounties three times, and in a personal email to me he said they seized all his records. (I don’t expect that Rick kept the most rigorous medical records anyway, but how much can or should one man do? He’s done his huge part.)
“There are many countries out there without big pharma (Cuba, Iran, Bolivia, Venuzula, Argentina).”
I’ve had the same question, but it might take a social psychologist/political scientist/philosopher and a lot of research to give a good explanation. Here are my ideas:
Don’t expect a burst of enlightened rationality just outside our borders–or anywhere. Basically medicine in 3rd world countries is going to follow 1st world examples in science, if not in economic rationing (provision of medical care). Techno-science is dazzling to them, just as it is to us.
Repressive regimes of any stripe oppose recreational drug use. The last I heard, Iran had the death penalty for some illegal drugs. Dubai or Bahrain was sentencing travelers passing through their airport to several years in jail for the tiniest possible flakes of herb. In the case I heard of, the minuscule amount of MJ was caught in the tread of a shoe. I think the reasons for such repression are psychological, deeply embedded in the unconscious, and institutionalized in laws. Wilhelm Reich may have identified that long ago.
Countries with the slightest friendly inclinations toward the U.S. are strong-armed by U.S. drug policy enacted through the U.N. as well as direct inter-country treaties. Now the U.N. is even returning the favor by protesting that two of our states have legalized marijuana use.
Many dictators and others are on the U.S. military dole. They don’t want to piss off their supplier.
The U.S. would be happy to allege that Cuba or other enemies are running drugs into this country. I’m sure the allegation has been made. Cuba would not want to give any credence to such stories. And who would they sell to?
Doctors in those countries may want to escape, emigrate, or even just train here. You won’t find them challenging U.S. drug policy. Third world countries are deeply aware of their shortcomings compared to us–they don’t want another reason to risk ridicule.
In 1995 I personally funded the visit here of a Russian M.D. who was experimenting with ketamine at psychedelic doses to treat alcoholism, but he was careful to try to fit his research into acceptable U.S. paradigms. He chose ketamine to work with because it has accepted medical uses, rather than using herbal psychedelics–although they probably weren’t available in Russia anyway. He ended up with a fellowship to spend a research year at Yale.
Look instead to 1st world countries with more liberal attitudes. Holland doesn’t just have hashish in coffee shops; I’ve seen videos of patients being prescribed cannabis and getting their scripts filled. England and Canada are growing cannabis and marketing a new cannabis drug, Sativex. Important research is being done in Spain, Italy, and Israel. Portugal has decriminalized all drugs.
It takes time…and people willing to push the envelope.
Hi Scott,
Thanks for your detailed and thoughful reply.
With regards to the uploading personal medical files. I would certainly upload them withholding personal information. I would also probably use software to hide upload location. However, I do agree that piling all this responsibility on one person is not fair.
I agree with your points of why these other countries have not investigated the possibilties. You raise a variety of interesting points that seem to ring true. However, I’m sure if money was raised by ‘the people’ using various crowdsourcing sites it be more likely a non aligned country will allow research in there country.
Sativex is certainly progress (even though its very difficult to get a prescription) and they certainly wont prescribe to cancer patients.
Scott, you clearly knowledgeable in this area so i would like to ask you a question. I’ve read that some mention the CBD percentage is important and others say its a high THC percentage thats important. I would appreciate it if you cold let me know your thoughts on what yuo think the optimum percentages are.
Many Thanks
My question about uploading personal medical information was rhetorical–designed to let you answer your own question about why you don’t see more medical data from users on the web.
Regarding THC:CBD ratios–I don’t have any idea, but I have probably seen some of the same speculation as you. If I were in a position to need the treatment, I’d try just about anything I could get my hands on.
S.
I thought I posted this but don’t see it so will re-post. Thank you all for your thoughts and support! Dennis, may your recovery be speedy and permanent! You are an inspiration and kind heart.
Hemp oil is a direction we would like to take. However, we have to find a way to navigate the residency requirements and legal issues while living in a prohibited state. So far, I’ve not had time to find a viable way around it. Any suggestions are welcomed! Anon
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Hi Dennis, just wanted to say that you are an inspiration to me. Been diagnosed with a very rear cancer last year. Been on oil for de past 4 months, with a break of 3-4 days each month. The thing I want to mention is the fact that I cannot take more than 0.2 gramms a day. I get really stoned. Just don’t know how come people take 1 gram per day. I bought my oil from Amsterdam.(I live in Europe)
My question to you is: do you think that the small amount I am taking will destroy my cancer or I should try to increase the daily dose?
Thank you!
Petre – It sounds like you have a high THC strain. It might be better for you if you could find oil from a strain that is 1:1 THC:CBD; as the CBD inhibits the high of the THC, yet is highly therapeutic for cancer without the intoxicating effects of THC. ~Dennis
Also make sure the dispensary is not using Skunk, which has been bred to contain 0% (or close to it) CBD. Not only does CBD help THC last longer in the system, it has its own cancer-killing capabilities and it mellows the high caused by THC (which is why Skunk is said to be more powerful – it gets you higher because CBD is not there to counteract THC’s psychoactive effects). See http://patients4medicalmarijuana.wordpress.com/2013/01/26/marijuana-is-it-medicine-yet-cannabis-for-pain-and-palliative-care-with-dr-donald-abrams-clint-werner/ Dr Donald Abrams speak on CBD at 13:00 minutes in.
Hi Dennis,
First of all thank you for answering my question.
I will try to find out the exactly % of thc and cbd and will let you know. You mention above about the oil being decarboxylated. I have no idea how it is but will also try to find out. The only problem would be that I don’t know another supplier here in Europe.
My regards,
Petre
Hello Dennis,
Hope you are well…..and good for you for taking medicine into
your hands….before others…
We have a dear friend whose PSA is rising quickly….his prostate
cancer has returned after 5 years….he is looking at alternative
therapies….he is done with the usual cut..poison…and burn..
His PSA is only .25 but will soon get to 1.0 or 2.0 per his
oncologist….. should he decide to use the Rick Simpson protocol
would he still need 60 grams over 90 days…. or could he get by
with less…..he’s not a pot user …. and is worried he would be stoned all day……
Merci….
i
A PSA of 0.25 is very low. Abnormal starts about 4.0. It will be up to the patient whether he starts alternative treatment. He should research the available literature and decide if this is what he wants to do. There is certainly no harm in trying the cannabinoid route. If he doesn’t like being stoned, then he should investigate CBD as the therapeutic agent. My sincerest wishes for a rapid recovery. ~Dennis
CBD tincture is awesome and sold now online by Dixie botanicals
Hi Dennis,
Thanks for your response….
He has decided to go the Rick Simpson route…
Since his PSA is low…. .25 do you think a protocol of 30 grams…over the course of two months would be sufficient to knock down his PSA to .01 or less…? and from what he has read and seen….he believes this can be done ….he’s changed his diet…become a vegetarian…and his lifestyle… is starting to
meditate….and take up yoga….
he has no problem being stoned daily for a few months…if he can get his PSA down and keep it down….assuming all goes well..
what do think would be an appropriate maintenance dose…..?
Also he has been taking vitamin B17… from the seeds in apples
and apricot pits…any harm in continuing….. or is it wise to stop..?
Keep up your good work !!
Your story has most definately inspired him…to change his life..
for the better…
Regards…… a friend of Gord,
Charles
You can follow Rick Simpson instructions, I have nothing to add to that. If Gord has had good results with B-17, it should be okay to continue. Use common sense plus your best information.
Anonymous says: January 29, 2013 at 10:21 pm Dear Admin, I’m getting lost in all the science again. I looked at Dixie botanicals http://dixiebotanicals.com/products/dew-drops-hemp-oil-supplement/
Are these the products that you said were THC infused? If infused wiwill it not provide the same healing properties as non-infused?
THank you so much-Anon
Dew drops hemp oil supplement is CBD.under. 3% THC.That’s why it is legal to ship. If you have a severe problem go with stronger solution. Ive been taking this for a month for my chronic candida I have had for 28 years. Its a game changer. Gives pain relief mental clarity and focus and general happy feeling without stoned.and shows great results for cancer Ms Alzheimer’s etc.!
The link anonymous just gave is the correct one for CBD products.
my husband has prostate cancer and we are in a prohibited state. Does the Dew drop meet all the criteria as prescribed by Rick Simpson, decarboxylated and potency? Thank you so very much!
Dixie dew drops is CBD concentrate. Rick Simpson oil is high thc concentrate. Totally different type of product. Both seem to be effective but dew drops can be shipped to all 50 States which makes them good for many people in non medical marijuana States. Maybe I have confused matters by bringing it up on this site but I feel its very important info
Dear Dennis, Admin, or Tim: it looks like the CBD from Dixie Dew Drops is a viable option. They also have capsules. Can you provide some guildance on doseage for either the drops or capsules? I know what RSO suggested dosage is but have no idea with these products. Thank you so much! Anon
Dear Dennis, Admin, or Tim: CBD from Dixie Dew Drops looks like a viable option. They also have capsules. Can you provide some guildance on doseage for either the drops or capsules? I know what RSO suggested dosage is but have no idea with these products. Thank you so much! Anon
Can anyone advise on the dosage for either the drops or capsules of CBD from Dixie Dew Drops? thank you! Anon
Anon,
I’m going to be blunt. I have 20 years experience working with the legal ramifications of cannabis. You may be completely sincere, but your questions remind me of an undercover police officer trying to set someone up. You have essentially all the information that anyone else here does, and certainly more than enough to start finding your own answers. Why don’t you come back when you have some information for us?
Hi Scott, I understand your comment and appreciate your concern. I am not an undercover cop. My husband has prostate cancer and I am trying to find answers for him. I thought that perhaps someone could advise on the CBD as it is different from the THC. I don’t want to make mistakes as we are fighting time. I don’t know how to convince you unless I post his lab findings. I wish I was a cop trying to bust people rather than a wife who is looking for answers. I apologize if I’m asking inappropriate questions on this forum but thought that there were scientists here who could advise. Because CBD is legal to ship I didn’t think that it was an inappropriate question. I would be willing to speak with you if there was a way to not have my personal information on the internet forever. Thank you. Anon
If you are fighting time, then why are you waiting to do something? I see plenty of answers already on this forum. Questions are a poor substitute for action. If you want more information, find a doctor who is a member of the Society of Cannabis Clinicians. http://societyofcannabisclinicians.com/ Most anyone else who tried to answer your questions would end up endangering themselves.
Scott. I appreciate your answers. I just learned of hemp/CBD about a month ago as well as the diagnosis of cancer. I’ve been trying to gather as much legitimate information as rapidly as possible. This seems like the most reliable site I’ve found on the internet. It’s all overwhelming. I thank you for your time. I would never want to put anyone in harm’s way! I am not trying to cause any problems. I will look at your link. Again, THANK YOU!
Scott, thanks for the nudge. Ordered from Dixie Dew Drops. Went with the capsules. Hope it works. A friend of ours just had surgery from prostate cancer and it did not go well. We really want to avoid the cut and burn methods! Thank you again!
This is the ugly result of cannabis prohibition. It has to be said. It is just so sad that we can’t speak freely about healing cancer with an herb. It is a violation of human rights to put fear into the hearts of the suffering, and those coming to their aid. Hopefully soon this medicine will be available as will good information about how to use it.
As for CBD, there has been science showing it stops the growth of cancer cells. I have no idea what amount one would have to take to get those results, if at all. They haven’t started human trials yet.
Basically, from what I understand, it takes high doses of cannabinoids to heal cancer. I don’t know how that translates when you’re talking about CBD pills. All of this “we don’t know” is due to prohibition. The government literally won’t allow scientists to do the research.
Blessings to you.
If I had cancer, then I’d be looking for the most pure RICK SIMPSON OIL (RSO) available! (95% THC or better!!!) Then I’d administer the oil according to Rick Simpson’s suggestions and let the healing begin. Anything less for me, my friends and family is unacceptable. If you want to cure CANCER…why mess around with the less potent oil? Good luck with the other oils
PEACE!
To John W: I appreciate your advice about getting the best treatment possible for cancer. We are law abiding citizens and the fear of going to prison outweighs the fear of allopathic medicine for my husband. The best plan I’ve been able to come up with in a month is the CBD capsules. I read the post with Nathan Kisper’s name and after reading the post about me being an undercover cop I’m even more frightened. I know of people who have been imprisoned for drugs and that’s a battle I don’t want on top of the cancer fight. I am very open to suggestions however! Anon
One more thing to John W. We leave in a prohibited state. Not even close to considering.
Warning – There is someone who speaks broken english, who is spamming this site with talk about some doctor’s ‘special’ hemp oil.
I erase every comment from them and block their IP, but they keep coming back.
When asked where the doctor is licensed, one is told you need an attorney to get that information!
This is a SCAM.
Preying on people who are sick will NOT be tolerated -
CONGRATULATIONS!!! You saved your life! You KILLED the cancer with the oil. Cannabis has been used for health and healing for more than 12 thousand years, documented. The doctor was simply a conduit, channel , for your healing process. The PLANT is the DEITY here. Your doctor is STELLAR for recommending the oil. I produce my own Rick Simpson Oil following Rick Simpsons method religiously! I’m just curious to know what were the levels of THC/CBDs/CBNs that your medicine contained to effect the healing you received. THAT is what will help us to accrue the necessary data to enhance our desire to help heal ourselves and others. THANKS SO MUCH! WE ARE ONE!
Sorry, I had to erase the comment to which you were replying. That person is trying to sell something and/or get people’s information.
@Admin I know. I was just trying to be nice. THANKS!
Thank you for looking out for people! Anon
You’re most welcome. Dixie is on the up and up.
I found 89% thc oil – is that good enough to help my mom with stage 4 cancer? I know you say 95% or higher but it’s very difficult to find if you don’t live in a legal state. Should I plan to give her more than 60 grams? She’s only a couple of days into it at this point.
I seem to recall that someone said 92-93% oil is the minimal THC for curing cancer according to the 60/90 suggestion. Again, that’s what I recall hearing. Please don’t use this as your final… but I do recall the discussion and numbers. PEACE!
Consulted Dennis, he said:
” The highest I’ve ever seen is 48% (White Widow). Can’t even imagine double that potency “
Somewhere on this post 95% thc is mentioned….why are you saying 48% is the highest?
It would be helpful if you can tell us the strain of cannabis that is 95% THC. Thanks.
~Dennis
Our strain was White Fire OG Kush which tested at 95.51%THC (the highest ever tested at Greenleaf Laboratories here in Portland, Oregon [out of >100K tests] and the CBDs at 1.54% and the CBNs at 2.06%. We were surprised too. We follow Rick Simpson’s protocols 100% to get these results. If you’re using ethanol to process the bud material, then THAT might be the problem. Some solvents remove too much of the extraneous components (turpentines/chlorophyll etc) which then contaminates the oil…(the oil will appear BLACK when smeared over a piece of white paper) which should appear a clear amber color when smeared over a piece of white paper. The oil I produce is “Rick Simpson Oil” and not any other name
I will be very happy to tell you exactly how I made the oil, or you can get your own copy of Rick Simpson’s book..either way..RSO works! PERIOD! PEACE!
http://phoenixtears.ca/video-library/
Thank you very much for this information. Excellent.
~Dennis
Katie, is there anyway I can contact you without your giving identifying information here? Anon
Hi Dennis,
I am currently on Day#42 of a 90 Day ‘quest’ to kill my prostate cancer. I was diagnozed (bioposy) in March 2005. My Geason was 6 and stage 3, My urologist —plus a ulologist from Mayo Clinic in Rochester, Mn recommended that I have surgery. I decided NOT to do surgery, but instead began to investigate a number of alternative treatments. So far, I’ve managed to survive , athough My PSA has steadyily increased over the couse of the 8 years. It is now 21.9. I started at 5.7 eight years ago.
I am a retired science teacher who will soon turn 63 years old.Grandchild #9 just arrived form me yesterday morning (2:38AM).
I hope to have a ‘story’ of my own to tell. I hope we might have a chance to meet/talk some day soon. I might even consider flying/driving out sometime soon.
Rod
Hi Rod – if you would like to try the cannabis extract for treating your cancer, follow directions given by Rick Simpson “Run from the Cure” video. Most folks I know of have had good results. ~Dennis
Pingback: Biochemist Dennis Hill cured his stage 4 prostate cancer with … | How to Make Butane Honey Oil - BHO Guides & Information
Reblogged this on Bloom Room SF Blog and commented:
“In 2006, researchers in Italy showed the specifics of how Cannabidiol (CBD) kills cancer. When CBD pairs with the cancer cell receptor CB-2 it stimulates what is known as the Caspase Cascade, that kills the cancer cell. First, let’s look at the nomenclature, then to how Caspase kills cancer. Caspase in an aggregate term for all cysteine-aspartic proteases. The protease part of this term comes from prote (from protein) and -ase (destroyer). Thus the caspases break down proteins and peptides in the moribund cell. This becomes obvious when we see caspase-3 referred to as the executioner. In the pathway of apoptosis, other caspases are brought in to complete the cascade.9
Even when the cascade is done and all the cancer is gone, CBD is still at work healing the body. Its pairing at CB-2 also shuts down the Id-1 gene; a gene that allows metastatic lesions to form. Fundamentally this means that treatment with cannabinoids not only kills cancer through numerous simultaneous pathways, but prevents metastasis. What’s not to like. One researcher says this: CBD represents the first nontoxic exogenous agent that can significantly decrease Id-1 expression in metastatic carcinoma leading to the down-regulation of tumor aggressiveness.10″
i live in Ireland and have early stage prostate cancer, can you let me know where i can buy the oil that has been decarboxylated, i seem only to be able to buy hemp oil at the grocery store and its not the proper one. I would be so thankfull of any help you can give me.
Charlie
Charles,
The first thing you need to do it watch Rick Simpson’s video, “Run From the Cure” which is all over YouTube, and upon which all this blogging about cancer treatment is based. Everything after that will rely on your own initiative. It will be vastly easier for you if you live in an area which allows medical marijuana. Anywhere else, you can be sure that it’s illegal.
Good luck, and please post your medical results/experiences if you try it.
Okay thats true
so how do I get ahold of this miracle cure for my husband?
Debra,
Anyone answering your question is in effect engaging in a conspiracy to violate federal law, and becomes chargeable with a federal crime if you should act on that information–and perhaps even if you don’t. I’d have to check the law, and no one’s paying me to do that. But I’ve seen it used several times to convict people who had no direct involvement in the actual “crime” which later took place.
Still, there are so many potential violations and law breakers out there that the feds can’t begin to catch or even worry about them all, so the internet is running wild with information. For instance, all the medical marijuana shops operating openly in states that allow them are committing federal crimes–and they are brick and mortar establishments much more permanent than posts on this blog.
But I have strongly advised this blog not to allow informational exchanges about actually obtaining medicine being posted for fear that the blog itself then becomes liable for the actions of its readers.
So the short answer is no answer at all. But you can find it if you keep looking. Read the stories of others who have done it.
Good luck, and don’t make yourself a big target.
My first basal cell carcinoma appeared over 30 years ago under my right eye. The dermatologist cut it out and radiated it. Over 100 other basal and squamous cell cancers have been treated since.
Several years ago, a tenacious cancer appeared within my ear. The dermatologist treated it many times before a Mohs surgeon removed it’s top.
In 2005, the proctologist found cancer in six of nine prostate biopsies. But the aorta valve in my heart was replaced first due to a heart murmur. Then I received 43 prostate radiations.
As I recovered from the open-heart surgery, I lost the central vision of my right eye. The heart surgeon told me a tiny bit of plaque most likely got loose as a result of the aorta surgery, causing a central retinal artery occlusion. A vascular surgeon then cleaned my right carotid in case it was the source of plaque.
In 2010, a full-body Scan showed tumors in the center lobe of my right lung. Biopsies indicated adenocarcinoma. The pulmonologist, oncologist and thoracic surgeon agreed the gold standard of treatment was removal of that lobe.
After several more scans showed the tumors were growing, and after viewing the complexity of lobe removal (http:// http://www.ctsnet.org/sections/clinicalresources/thoracic/expert_tech-.html), I chose radiation treatment, thinking I’d have a better chance of surviving than going under the knife again. 24 radiations and 12 more scans confirmed the lobe was well zapped.
In the Fall of 2011, cancers were appearing in other lobes and another skin cancer was removed from the back of my ear. I was in between the scans scheduled to see when and where the next zapping would be done. Thankfully, a friend suggested I watch Rick Simpson’s internet film “RUN FROM THE CURE”. After watching, I thought “what have I got to lose”?
I got a Michigan Medical Marihuana license that November and made some cannabis oil. As I consumed the suggested dose by April, I was able to function normally. My children were unaware of my treatment until we told them in March. No “joint” smoking was involved.
Recent CT scans, X rays, Echo Cardiograms, EKG’s, carotid and aorta scans, blood tests, heart monitor test, and physical exams indicated I am free of cancer. Occasional skin cancers are now treated with the oil as they appear. I’m in my 80′s now and thankful to Jesus that I am again able to enjoy prayer, golf, scuba diving, racquetball and water skiing.
Obviously, I don’t know how this will all turn out. But I am reminded of Rick Simpson’s statement that the “healing powers of cannabis oil do not stop at cancer”. He said he not seen any disease that cannabis oil couldn’t cure, including cardiovascular disease, diabetes, Crohn’s disease, arthritis, multiple sclerosis, pain disorders, mental disorders, etc.
Over-dose of many medicines, even aspirin, can be fatal. If one takes too much cannabis oil, the effect wears off quickly and no harm is done. I have not heard of anyone dying from its use. I have also verified that it is no more addictive than the daily baby aspirin I used to take.
What if Cannabis Cured Cancer: Full Version – YouTube - 49′
http://www.youtube.com/watch?v=Hy66MUZP538
Run From The Cure The Rick Simpson Story (Full Version) – YouTube -58
http://www.youtube.com/watch?v=dvosdIXyjWM
Shona Banda’s interview show cannabis treats more than just cancer and that very little is needed to produce remarkable results:
http://sensiseeds.com/en/blog/shona-banda-and-medicinal-cannabis/ - 3′
Good morning sir.
Thank you for your job.
I’ve tried RSO for 6 months with my own production (good quality i think) My Psa went from 14 to 18.. (T2 minimum)…and now, the cancer went through the apex….now, i have to be very carreful….6 month was maybe not enough, or i didn’t took enough, i dont know….If you have an idea and time to tell it to me, it would be a great help.Thank you.
Philippe
suggest you get some good oil somewhere soon.
Thank you, it’s not easy and dangerous in France, i take a risk, even to write here, but chimio and consor is risky too,
To get it legally go to Spain, they have some very helpful Medical Cannabis Social Clubs. They will help you.
To kill cancer you have to hit it very hard with high potency, decarboxylated THC. If you did this, then I would expect better recovery.
~Dennis
Thank you very much Dennis.
My father has been recently ( a week ago) found that he has a prostate cancer were can we find this Madison called cannabis oil in south Africa
Hope is coming back, T.Y.
The point now is that they don’t want to remove the prostate, but check tne ganglions via a robot, then radiotherapy plus hormontherapy on a three years period.
Sorry, the above robot story is mine too.
anyone know if smoking extra production (i mean a lot) could brake or stop the rick’ cure? thank you for big help, for now, i’m lucky that the cancer didn’t went to the bone (metatstase) feel so stupid ,…
Some people are trying to get some money by telling a big cancer story on FB…i neraly felt on it…
I mean, i was about to send some money ( if i had some)
These links may provide good help & info.
http://www.forbiddenknowledgetv.com/videos/cannabis–hemp
Is there any hope for my husband with 900psa? I take the “oil” to him at the care home twice a day. He grows weaker by the day.
Wonderful that you take the oil daily to your husband. It always helps in some way, and is never harmful. This is a very sweet way to care for him. Perhaps we cannot know the outcome, but the caring is very important. ~Dennis
Dennis Hill has stated that it is very important to make sure the cannabis oil is “decarboxylated”. Does this take place automatically if the oil is processed according to the instructions on the phoenix tears site? From Dennis’ instructions on this site it would appear that the dried material must be first placed in the oven at around 240 degrees F for 30-45 minutes after going through a blender. Then after that one would go about making the oil as per Rick Simpson’s directions? Our Vita Mix blender would just make powder out of it.
I would think that distilling off the solvent from the oil would automatically decarboxylate it, but because Dennis Hill experienced some oil that wasn’t decarbo-ed, then maybe it doesn’t. What temperature is the solvent is being cooked off at?
I concur with MC above…. no need to “pre-bake” the bud material if the oil is to be made via the RSO way…LOL! GOOD LUCK!
I have not tried making it yet. Just trying to understand the process. It would be nice if Dennis could clarify this.
Thanks for any help.
If you plan to use the Rick Simpson method, make sure that the plant mass (or the extract) cooks for 30-45 minutes at 260º F. Some may think they follow Rick’s instructions, but if they do not know the importance of decarboxylation for cancer, it might get overlooked. If you use cannabis extract to kill cancer, use what ever method you like, but don’t neglect burning off the carboxyl group from THC and CBD.
~Dennis
“When cooker is turned on, thermal sensor will monitor cooking temperature. As water boil at 212 deg F so cooker will have temperature not higher than 212 F while rice is still wet with water. Immediately after water dry up, cooker temperature will rise above 212 F so cooker will turn off.” … “Some rice cooker has warming function. After rice is cooked and power is off, cooker still give some heat to cooked rice keeping it warm. This temperature normally about 150 F which will keep all microscopic activity at minimum, also will keep rice soft.” –http://www.gms-ain.org/Z_Show.asp?ArticleID=784
Rice cookers- a la the Simpson Method, only get as hot as the boiling point of the substance they are heating, since evaporation keeps the temperature from rising higher. Thus water evaporates at 212 deg F, so as noted above, rice cookers can’t heat the water any higher than that. Isopropyl alcohol evaporates at 180 deg. F. 190-proof Everclear boils at 173 deg F. Common naptha (VM&P) is a mixture which boils in a wide range from 68 to 167 deg F.
Conclusion: It appears that none of these solvents would boil hot enough to reliably decarboxylate THCA to THC.
RE: Clarifying the process of making RSO
The rice cooker and hot plate method which Rick Simpsons suggests using are both limited electronically to never exceed the maximum temperate that the oil ought never exceed during the cooking process, which I recall to be approx 295º
My validations have indicated that the oil in a standard 4 quart rice cooker usually hovers around 260º -280º at it’s hottest point in the distillation process. I validated the temperature with a a meat thermometer, a candy thermometer and a digital multimeter with a temperature probe/gauge.
The remaining steps in the process have to do with distillates, timing and temperature. Rick Simpson suggest using either of three distillates; 1) Ether – 2) 99% Isopropyl Alcohol – 3) Naphtha
Which either of the 3 is accessible/useful to you, take your pick
Locating a knowledgeable grower and/or gearing up to grow your own medical grade cannabis is a major step in the right direction. Rick Simpson suggest using “quality bud material” to get the best quality/grade of medicine that works best for treating most serious cancers (high THC/CBD levels) The quality of medicine produced is related to the particular strain, cultivation and curing methodologies. All the information one needs to produce RSO is in Rick’s book, “The Phoenix Tears” which can be obtained from the Phoenix Tears Foundation at the following link
I’ve made about 20 batches so far (using ≈25 pounds of quality bud material) and I’m seeing all the evidence a person needs to see that Rick Simpson Oil “REALLY” works! The reason for all the fuss about RSO -vs- any “other” cannabis oil has to do with the ratios of the usable components of the oil one gets when the cannabis is properly cooked (decarboxylated), which is the beauty of the RSO method. It’s simple to produce for a minimal costs…as long as one can grow or locate quality bud material and the distillates readily. Rick Simpsons process is tried, true and tested
Simply following Rick’s method precisely using one of the aforementioned distillates will obtain the desirable yield of pure RSO 
Hope this helps a little. GET THE BOOK ON RSO from Rick…it’s easily obtainable online at 
http://phoenixtears.ca/buy-phoenixtears-the-rick-simpson-story/
PEACE!
Thanks for clarifying the temperature issue. My observations were just theoretical.
Dear Dennis, I wrote to you a while ago mentioning my husband’s PSA 900. His abdominal region is swelling which I understand to be swelling of the liver. We are planning on bringing him home to manage possible larger doses of the “oil” at night when he won’t know how drunk he feels, which his problem has been each Time I make him a rice grain dose wrapped in bread to make a pill. Have you EVER heard of anyone that far along with prostate cancer heal? You can be truthful with me. I can take it. Thank you so so much for your quick response last time.
900 PSA is pretty high, but cannabinoid extract can still help. As he gets accustomed to the extract effects he can take more. During my treatment I took a large dose PM and small dose AM, which allowed me to work and drive.
Hi Dennis,
Charles leaves this comment:
Hi Dennis….
So glad to see that this medicine
does work….
We managed to acquire the oil..
all through the proper legal channels..
My friend… Started with .02 grams on
March 1/13….. and over 3 weeks
gradually increased his daily oil intake..
up to .50 gram by weight daily….
and since the last week he is able
to take a total daily dose of about 1.0
gram…the oil is of good quality….
A gas chromatograph indicated
THC purity at 85.15%
CBD purity at 2.01 %
He has injested a total of about 18.0
grams of RSO …..since March 1/13…
We are very optimistic… that this
medicine will slow down his PSA…
We have changed his diet…. He exercises
As much as possible… Is juicing…
cut out the red meat… no dairy…
lots of salads fruits and veggies…
His Gleason score was 9… Stage 3
Clear margins…. But spread to
the lymph nodes…. Is micro metastatic
….
We plan on continuing at 1.0 gram daily..
until his cancer is gone….
Any comments or suggestions…
Charles….
Once again, if you are killing cancer, it’s more potent if you start with 1:1 THC:CBD, as we know that CBD is effect at stopping the spread of the tumor.
~Dennis
@Dennis Last month I produced one batch of RSO from a strain that came out 38.85% CBD 54.95% THC and 4%CBN … that is close, but still not a 1:1 ration… More recently I produced a batch that is 9.03% CBD, 81.43 THC and 5.96 CBN as tested by Green Leaf labs here in Portland, OR. Do you have any suggestions about how to easily obtain a 1:1 ratio for cancer patients. Are there some symptoms which may benefit from higher THC rations to CBD ratios? I admit that I know very little (electronics engineer here, no bio-chemist
but am teachable and truly intend to help cancer patients because I CARE! If there is a better way to treat cancer patients, then I think they deserve to have untethered access to that treatment…and so do we who intend to help them. Thanks Brother Dennis. PEACE!
Hey, 38% CBD and 55% THC is close enough to 1:1; doesn’t have to be exactly 1:1. Just need to have CBD for control of metastasis. This is the basics, if you do this, there will be success. All cancer patients benefit from THC primarily to generate Ceramide to shred the mitochondria which starves the cancer cell. Next, you just have to keep it from coming back, with CBD.
~Dennis
I had one batch come out 95.51% THC, 1.52 CBD and 2.65 CBNs and am actually using some of that oil presently. Do you think that for my chronic pain issues/seizures that I would be better off medicinally to stick with the high CBD varieties instead of the high THC strains that all the stoners insist on? I’m still researching but appreciate some good advice on the main medicinal components of he cannabis plant and what each component is good for. PEACE!
I think you will need to experiment with various combinations to know for sure; but from what you describe, I think the 1:1 would serve well.
~Dennis
@Dennis
Could you please indicate if the material has to be dry before putting it in the oven to be decarboxylate or if we cut it and place it right in the oven, and this will make it dry.
Thank you ;
May your work receive the blessing it deserve.
`Philippe.
I recommend that you dry the plant material first (hang it on a rack), before decarboxylation. But you should experiment and see what works best for you. ~Dennis
Thank you again for theses pages and time for answering, I will do the same as soon as i’m finish with this cancer, maybe by translating some pages in French….
Philippe.
I do hope you get to do some translation, so that your countrymen (and women) have this information about treating cancer with cannabinoids. I like it a lot better than chemo and radiation.
~Dennis
Dennis, thanks a lot for the scientific background information you have provided. As well for your patience and time to answer all these questions. Here is my question. : Was there ever a moment that starting up with the very small dosis of the rick Simpson recipe oil that you got distracted in your day to day job and felt that you could not work because you were getting hi? or is it true that the starting with the very small dosis results is no high at all and that one might expect just to stay functional at ones job?. maarten
Maarten – if you are taking cannabinoid extract for cancer, best if you start small and increase as you build tolerance. THC gets you high, that is just the way it is. If you don’t want to get high, choose a different therapy. If you are not treating cancer, try CBD. That doesn’t get you high. If you take such a small dose that you don’t get high, then you are likely not getting enough to be therapeutic. This is the cost of using cannabis extract therapeutically. During my therapy I took a small dose during the day so I could drive and work. Then a large dose before bed, and just sleep through it. Best of luck to you. ~Dennis
i need some cannabis oil …can someone help me ? it is illegal in my country
If you come to Oregon, we can help you to obtain your Oregon Medical Marijuana Program “patient/caregiver/grower” cards to use, administer and grow medical cannabis. Then you can either grow your own cannabis and make your own RSO or if you are sick and cannot provide for yourself, then you may appoint another person to grow/provide your medical cannabis for/to you
If you are in another country besides the USA, then unfortunately we can NOT help you here in Oregon. However, if you are from ANY other state in the USA, “Oregon cares,” and we can and will help you. All you provide is a legal ID showing that you are a US Citizen along with any doctor’s statement and/or chart notes indicating a qualifying condition and then The Hemp and Cannabis Foundation (THCF) here in Oregon will be happy to help you to obtain legal access to the medicine which you require.
I would say that if you are from another country and you make it to Oregon, you are home… just look for clouds of smoke and lot of very happy people…at least those if us whom partake in the TREE OF LIFE ….
Hi John & Dennis
Hoping you may be able to help with a question:
1. This CBD/THC ratio is causing some confusion. I dont think there is a case (ie anecdotal) online I can find (apart from yourself (Dennis)) that suggests a 1:1 ratio. RSO doesnt mention it and I suspect a majority have approx 55%THC and <1% cbd. Do either of you happen to know of other people where the oil has helped reduce tumours and what concentrations they used ?
I don’t know anyone else; but the reason I recommend 1:1 is that we know THC kills cancer, but we also know the cancer can come back. CBD is known to inhibit metastasis, so it only makes sense to inhibit the cancer return. Do you think I am right about this? ~Dennis
We know of a local patient here, Cindy, who had a tumor that was making her blind and here headaches were murderous! After a couple of weeks of using a high THC “and” high CBD oil made per Rick Simpson’s method, Cindy experienced a remarkably fast from a near fatal situation. Cindy continues to improve. Her latest MRI 6 months later cannot detect a tumor at all where once “golf-ball-split-in-half” sized tumors had once resided behind Cindy’s eyes, threatening her life. Cindy’s story will be told more fully by Cindy herself in the coming months
Hello John & Dennis,
My name is Pete and have a very rare type of cancer.
Regarding Cindy, would you be able to provide me with more information about the oil she’s been taking and the name of the tumour she had!
John, you are saying that she used a high thc ‘and’ high cbd oil! What is that mean? What are the procentaj of thc and cbd used.
Also i am asking about the name of her tumour because mine is located more or less in the same aria, under the skull base, not far from optical nerve.
Thank you in advance!
Sent from my iPhone
Excellent news. we really need a wordpress site where we can upload anecdotal evidence in an organised format:
eg
Strain, ratios, amount, time taken for response, type of chemo (if any) etc
I dont know. So I guess I’ll be trying both ratios. The best I can find at the moment is 4:1.
I’m leaning towards your CBD point due to the article below article from reputable Nature magazine (refer to page 7, middle column, first paragraph).
…sorry, i cannot paste links. You can search for “Towards the use of cannabinoids as antitumour agents” its by Guillermo Velasco, Cristina Sánchez and Manuel Guzmán
I also found this on page 4 of the same nature article:
“It is worth noting that CBD, by acting
independently of CB1 and CB2 receptors,
produces an antitumour effect — including,
the reduction of invasiveness and mestastasis
— in different animal models of cancer
(Supplementary information S1 (table)).
This effect of CBD seems to at least partly
rely on the downregulation of the helix–
loop–helix transcription factor inhibitor of
DNA binding 1 (ID1)58,59.”
“her headaches” …and “remarkable fast recovery” …sorry
PEACE!