Biochemist Dennis Hill, who cured his stage 4 prostate cancer with Cannabis oil, explains how it works

This article was recently mentioned in the Metro Times Detroit

Most recent update from Dennis Hill (2.28.13):

  • My progress is good. Asked my doctor the meaning of my last three PSAs. He said: The PSA has not risen over 2.4 in nine months, we can presume the cancer is in remission. Music to my ears. Cannabinoid extract wins again. Huzzah!

Previous update (12.8.12):

  • After six months using cannabis extract, a prostate biopsy confirmed the cancer was gone, in February 2010. Twenty months later, biopsy showed cancer had returned. I have reinstated cannabis extract and PSA is declining. I expect the cancer to be gone soon, just as it did previously.

On the need to decarboxylate medicine: 

  • “My co-op hash oil had not been decarboxylated. THCA does not fit the CB-1 receptor that is required to send seramide to the work of apoptosis.” (This is why the cancer made a reappearance)
    How to decarboxylate

Retrospective on Cannabis and Cancer – Dennis Hill

Three years ago, after a prostate biopsy, I was given the diagnosis of aggressive Stage III adenocarcinoma. I didn’t know what to do. The urologist made appointments for me to start radiation, and maybe chemo. Then a friend told me cannabis cures cancer. It just so happened that the first human trials of cannabis treatment of astrocytomas (inoperable brain cancer), were published with encouraging results. So I decided; rather than die from the medical treatment, I would do the cannabis cure. Now… where to get some. There was no dispensary in the area, but a friend made me cannabis butter, so I took that, up to tolerance. In three months the primary cancer was gone, only minor metastatic lesions were left. At that point I found a supplier for Rick Simpson oil and killed off the metastases in the next three months. Now I just take a maintenance dose of locally produced hash oil that is 1:1 THC:CBD with about a 30% potency. This will certainly keep me clear of cancer, anywhere, for ever.
My point in telling this story is the fact that in the face of advanced aggressive cancer, all I had was very weak cannabutter, but it was enough to eliminate the primary tumor. Now there are strains of 95% THC. But is this necessary? If you have cancer and want to pursue the cannabis treatment, any at all will be good. More important than extreme potency, is balance between THC and CBD. If you can get high potency, great. If not, common potencies will work perfectly.
Finally, if you choose cannabinoid treatment, start small, then increase dosage as rapidly as tolerable. To kill cancer you have to hit it hard, be conscientious about your treatment. Cannabis does no harm to the body, it is a metabolic support for the immune system.


Here are the basics, based on my own experience with cancer and cannabis oil extract.
  • Get Rick Simpson formula oil; including the important decarboxylation step to convert THCA to THC.
  • If possible, use 1:1 THC:CBD, as THC kills the cancer, CBD kills the cancer’s ability to metastasize.
  • Take as much as possible; the way to kill cancer is to hit it very hard. Start very small to acclimate to the oil properties, then keep increasing the dose as tolerable.
  • Take a large dose before bed, then a lighter dose during the day, to keep the pressure on the cancer.

This is how I managed my prostate cancer to have a successful resolution. ~ Dennis Hill (4.11.13)


A condensed version of the two videos to follow:

From Cannabis Nation Radio

  • Read Dennis Hill’s Curing Cancer With Cannabis Extract: a Journal
  • Learn to make Cannabis Oil
  • Notes: Cannabis and Marijuana oil/extract are terms used interchangeably to refer to Rick Simpson’s “Hemp Oil” (“RSO”). In Canada, where Rick is from, Hemp refers to cannabis. In the US, Hemp refers to the non-THC bearing plant used for textiles etc.; “Hemp Seed Oil” is sold legally, but is not the same as Rick’s high-THC “Hemp Oil”.

How to make a small batch of cannabis extract, or Rick Simpson Oil (RSO):

From Cannabis Nation Radio Biochemist Dennis Hill graduated from the University of Houston and did his Graduate Work at Baylor Medical School. Dennis worked as a Cancer Researcher at the MD Anderson Cancer Center in Houston. When Dennis was diagnosed with advanced stage prostate cancer, which had metastasized to other parts of his body, he started researching. Since Dennis has a family history of prostate cancer, and he often witnessed ineffective results while working in cancer research, he felt a new approach was in order.

After researching possible alternatives Dennis ran across information about Rick Simpson using cannabis concentrate, which is an extract of the essential oil which is extracted from marijuana and contains cannabinoids. Simpson was using the oil to treat a wide variety of illness, including cancer. The more Dennis researched, the more he understood how cannabis worked on cancer. He has included 2 papers for the review of anyone interested that go into the science of how cannabis kills cancer. He was determined to give it a try, and decided to tell his doctor that he would be using cannabis concentrate alone for his treatment. He did not want to risk more damage to his body from chemo, so he chose to start the cannabis oil regime without any other treatment.

Dennis is educated, with a sound background in science, and a background in the cancer industry. He stated that the Cannabis Oil killed the cancer, and he is now cancer free. He never underwent any of the standard treatment ie chemo, or radiation. He maintained a healthy diet, and exercise as part of his healing and after care. Dennis worked two jobs while he was treating himself, and never experienced any of the side effects typically associated with standard cancer treatments. He administered 1 tiny dose of the cannabis oil in the AM, and 1 tiny dose of the cannabis oil in the pm, just as Rick Simpson suggests.

Here, Dennis Hill explains the inner workings of cancer death-by-Cannabinoids:

Cannabinoids and cancer

Cancer-specific Cytotoxicity of Cannabinoids

By Dennis Hill (reprinted with permission)

First let’s look at what keeps cancer cells alive, then we will come back and examine how the cannabinoids CBD (cannabidiol) and THC (tetrahydrocannabinol) unravels cancer’s aliveness.

In every cell there is a family of interconvertible sphingolipids that specifically manage the life and death of that cell. This profile of factors is called the “Sphingolipid Rheostat.” If ceramide (a signaling metabolite of sphingosine-1-phosphate) is high, then cell death (apoptosis) is imminent. If ceramide is low, the cell will be strong in its vitality.

Very simply, when THC connects to the CB1 or CB2 cannabinoid receptor site on the cancer cell, it causes an increase in ceramide synthesis which drives cell death. A normal healthy cell does not produce ceramide in the presence of THC, thus is not affected by the cannabinoid.

The cancer cell dies, not because of cytotoxic chemicals, but because of a tiny little shift in the mitochondria. Within most cells there is a cell nucleus, numerous mitochondria (hundreds to thousands), and various other organelles in the cytoplasm. The purpose of the mitochondria is to produce energy (ATP) for cell use. As ceramide starts to accumulate, turning up the Sphingolipid Rheostat, it increases the mitochondrial membrane pore permeability to cytochrome c, a critical protein in energy synthesis. Cytochrome c is pushed out of the mitochondria, killing the source of energy for the cell.

Ceramide also causes genotoxic stress in the cancer cell nucleus generating a protein called p53, whose job it is to disrupt calcium metabolism in the mitochondria. If this weren’t enough, ceramide disrupts the cellular lysosome, the cell’s digestive system that provides nutrients for all cell functions. Ceramide, and other sphingolipids, actively inhibit pro-survival pathways in the cell leaving no possibility at all of cancer cell survival.

The key to this process is the accumulation of ceramide in the system. This means taking therapeutic amounts of cannabinoid extract, steadily, over a period of time, keeping metabolic pressure on this cancer cell death pathway.

How did this pathway come to be? Why is it that the body can take a simple plant enzyme and use it for healing in many different physiological systems? This endocannabinoid system exists in all animal life, just waiting for it’s matched exocannabinoid activator.

This is interesting. Our own endocannabinoid system covers all cells and nerves; it is the messenger of information flowing between our immune system and the central nervous system (CNS). It is responsible for neuroprotection, and micro-manages the immune system. This is the primary control system that maintains homeostasis; our well being.

Just out of curiosity, how does the work get done at the cellular level, and where does the body make the endocannabinoids? Here we see that endocannabinoids have their origin in nerve cells right at the synapse. When the body is compromised through illness or injury it calls insistently to the endocannabinoid system and directs the immune system to bring healing. If these homeostatic systems are weakened, it should be no surprise that exocannabinoids perform the same function. It helps the body in the most natural way possible.

To see how this works we visualize the cannabinoid as a three dimensional molecule, where one part of the molecule is configured to fit the nerve or immune cell receptor site just like a key in a lock. There are at least two types of cannabinoid receptor sites, CB1 (CNS) and CB2 (immune). In general CB1 activates the CNS messaging system, and CB2 activates the immune system, but it’s much more complex than this. Both THC and anandamide activate both receptor sites. Other cannabinoids activate one or the other receptor sites.Among the strains of Cannabis, C. sativa tends toward the CB1 receptor, and C. indica tends toward CB2. So sativa is more neuroactive, and indica is more immunoactive. Another factor here is that sativa is dominated by THC cannabinoids, and indica is predominately CBD (cannabidiol).

It is known that THC and CBD are biomimetic to anandamide, that is, the body can use both interchangeably. Thus, when stress, injury, or illness demand more from endogenous anandamide than can be produced by the body, its mimetic exocannabinoids are activated. If the stress is transitory, then the treatment can be transitory. If the demand is sustained, such as in cancer, then treatment needs to provide sustained pressure of the modulating agent on the homeostatic systems.

Typically CBD gravitates to the densely packed CB2 receptors in the spleen, home to the body’s immune system. From there, immune cells seek out and destroy cancer cells. Interestingly, it has been shown that THC and CBD cannabinoids have the ability to kill cancer cells directly without going through immune intermediaries. THC and CBD hijack the lipoxygenase pathway to directly inhibit tumor growth. As a side note, it has been discovered that CBD inhibits anandamide reuptake. Here we see that cannabidiol helps the body preserve its own natural endocannabinoid by inhibiting the enzyme that breaks down anandamide.

In 2006, researchers in Italy showed the specifics of how Cannabidiol (CBD) kills cancer. When CBD pairs with the cancer cell receptor CB-2 it stimulates what is known as the Caspase Cascade, that kills the cancer cell. First, let’s look at the nomenclature, then to how Caspase kills cancer. Caspase in an aggregate term for all cysteine-aspartic proteases. The protease part of this term comes from prote (from protein) and -ase (destroyer). Thus the caspases break down proteins and peptides in the moribund cell. This becomes obvious when we see caspase-3 referred to as the executioner. In the pathway of apoptosis, other caspases are brought in to complete the cascade.9

Even when the cascade is done and all the cancer is gone, CBD is still at work healing the body. Its pairing at CB-2 also shuts down the Id-1 gene; a gene that allows metastatic lesions to form. Fundamentally this means that treatment with cannabinoids not only kills cancer through numerous simultaneous pathways, but prevents metastasis. What’s not to like. One researcher says this: CBD represents the first nontoxic exogenous agent that can significantly decrease Id-1 expression in metastatic carcinoma leading to the down-regulation of tumor aggressiveness.10

This brief survey touches lightly on a few essential concepts. Mostly I would like to leave you with an appreciation that nature has designed the perfect medicine that fits exactly with our own immune system of receptors and signaling metabolites to provide rapid and complete immune response for systemic integrity and metabolic homeostasis.

Sami Sarfaraz, Farrukh Afaq, Vaqar M. Adhami, and Hasan Mukhtar + Author Affiliations. Department of Dermatology, University of Wisconsin, Madison, Wisconsin
J Neuroimmunol. 2007 Mar;184(1-2):127-35. Epub 2006 Dec 28.
Immune control by endocannabinoids – new mechanisms of neuroprotection? Ullrich O, Merker K, Timm J, Tauber S.
Institute of Immunology, Medical Faculty, Otto-von-Guericke-University Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany.
Endocannabinoid synthesis & release.
Cannabinoid receptor type 1.
Journal of Neurochemistry, Volume 104 Issue 4, Pages 1091 – 1100
Published Online: 18 Aug 2008
Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb.
Angelo A. Izzo, Francesca Borrelli, Raffaele Capasso, Vincenzo Di Marzo, and Raphael Mechoulam. Department of Experimental Pharmacology, University of Naples Federico II, Naples, Italy. Institute of Biomolecular Chemistry, National Research Council, Pozzuoli (NA), Italy. Department of Medicinal Chemistry and Natural Products, Hebrew University Medical Faculty, Jerusalem, Israel, Endocannabinoid Research Group, Italy
Scientists test medicinal marijuana against MS, inflammation and cancer
By Nathan Seppa June 19th, 2010; Vol.177 #13 (p. 16)
NIH Public Access:
A house divided: ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell death
Tarek A. Taha, Thomas D. Mullen, and Lina M. Obeid
Division of General Internal Medicine, Ralph H. Johnson Veterans Administration Hospital, Charleston, South Carolina 29401; and Department of Medicine, Medical University of South Carolina, Charleston, South Carolina 29425
Corresponding author: Lina M. Obeid, M.D., Department of Medicine, Medical University of South Carolina, 114 Doughty St., P.O.Box 250779, Charleston, South Carolina 29425. E-mail:
9. P. Massi, A. Vaccani, S. Bianchessi, B. Costa, P. Macchi, D. Parolaro
Cellular and Molecular Life Sciences CMLS
September 2006, Volume 63, Issue 17, pp 2057-2066
10. Mol Cancer Ther. 2007 Nov;6(11):2921-7.
Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells.
McAllister SD, Christian RT, Horowitz MP, Garcia A, Desprez PY.
California Pacific Medical Center, Research Institute, 475 Brannan Street, San Francisco, CA 94107, USA.

The Human Endocannabinoid System Meets the Inflammatory Cytokine Cascade

By: Dennis Hill
The Endocannabinoid System (ECS) started revealing itself to researchers in the 1940s and by the late ’60s the basic structure and functionality had been laid out. Today we know the ECS is a comprehensive system of biochemical modulators that maintain homeostasis in all body systems including the central and peripheral nervous systems, all organ systems, somatic tissues, and all metabolic biochemical systems, including the immune system.

This homeostatic matrix is not a recent evolutionary twist just for humans; we Find the Endo cannabinoid System in every chordate creature for the last 500 million years. It is a fully mature biochemical technology that has maintained health and metabolic balance for most of the history of life itself.

The two major interactive systems within the ECS are (1) the cannabinoid receptors that we find on all cell surfaces and neurological junctions and (2) the endocannabinoids that hit the receptors to trigger various metabolic processes. Looking at a cannabinoid receptor distribution map we see that CB1 receptors, that are most sensitive to anandamide, are found in the brain, spinal nerves, and peripheral nerves. CB2 receptors preferred by 2-arachidonoylglycerol (2-AG) are found largely in the immune system, primarily the spleen. A mix of CB1 and CB2 receptors are found throughout the rest of the body including the skeletal system. And yes, 2-AG or CBD will grow new trabecular bone.1 It is also useful to note that both anandamide and 2-AG can activate either CB1 or CB2 receptors.

The nature of the endocannabinoids are functionally much like neurotransmitters, but structurally are eicosanoids in the family of signaling sphingolipids. These signaling cannabinoids keep track of metabolic systems all over the body. This information is shared with the nervous system and the immune system so that any imbalance is attended to. If the body is in chronic disease or emotional stress, the immune system can fall behind and lose control of compromised systems. It is here that phytocannabinoids can pitch in to support the stressed body in a return to health. The cannabis plant provides analogues of the body’s primary signaling cannabinoids. Tetrahydrocannabinol (THC) is mimetic to anandamide, and cannabidiol (CBD) is mimetic to 2-AG, and has the same affinity to CB1 and CB2 receptors; providing the body with additional support for the immune and endocannabinoid systems.

Phytocannabinoids supercharge the body’s own Endocannabinoid System by amping up the response to demand from the immune signaling system in two modes of intervention: one, of course, is in bonding with the cannabinoid receptors; the other is in regulation of innumerable physiological processes, such as cannabinoid’s powerful neuroprotective and anti-inflammatory actions, quite apart from the receptor system. It is interesting to note here that the phytocannabinoids and related endocannabinoids are functionally similar, but structurally different. As noted above, anandamide and 2-AG are eicosanoids while THC and CBD are tricyclic terpenes.

Let us look more closely at the two primary therapeutic cannabinoids, THC and CBD. The National Institutes of Health tell us that THC is the best known because of its signature psycho- tropic effect. This government report shows THC to be effective as an anti-cancer treatment, an appetite stimulant, analgesic, antiemetic, anxiolytic, and sedative.2

CBD (cannabidiol) is a metabolic sibling of THC, in that they are alike in many ways but are also different in important properties. First we see that CBD has no psychotropic effects and there are few CB2 receptors in the brain and peripheral nerves. There appears to be a broader therapeutic profile associated with CBD, which is listed here:

One of the most important health benefits of cannabinoids is their anti-inflammatory property. In this, they are strong modulators of the inflammatory cytokine cascade. Numerous disease states arise out of chronic inflammation; such as, depression, dementias including Alzheimer’s, cancer, arthritis and other autoimmune disorders, viral infection, HIV, brain injury, etc.

Inflammatory cytokines can be activated by oxidative stress and disease states. Cannabinoids, being immunomodulators interrupt the cytokine inflammatory cascade so that local inflammation does not result in tissue pathology. Thus we are spared morbid or terminal illnesses.4
If our own endocannabinoid system can maintain metabolic homeostasis and even cure serious disease, why are we plagued by illness? We know that the body produces only small amounts of anandamide and 2-AG; enough to maintain the body but not enough to overcome chronic stress, illness, injury, or malnutrition. Cannabis is the only plant we know of that produces phyto- cannabinoids that mimic our own endocannabinoids. One of the great benefits of this mimetic medicine is that cannabinoids are essentially natural to our biology and do no harm to our tissues and systems.

It is well known that most diseases of aging are inflammatory in origin, thus making cannabis the best anti-aging supplement we could take to avoid arthritis, dementia, hypertension, diabetes, osteoporosis, and cancer. This is our key to good health and long life.

Since it is such an important attribute, as well as being independent of the cannabinoid receptor system, let’s look a little deeper into the ability of cannabinoids to inhibit the inflammatory cytokine cascade. Inflammation is good for us, a little here, a little there; it brings T-cells and macrophages to infection sites. This is good. However, chronic inflammation can cause serious illness and death. How do phytocannabinoids rescue us from dreaded infirmities? When the call comes in to the immune system to send troops, the First thing to happen is that the immune system signals glial cells to produce cytokines. Once this cat is out of the bag, the process can go one of two ways.

A) Killer cells clean up the infection and all is well.

B) Cytokines can stimulate more cytokine production and cause many more cytokine receptors to awaken. Unchecked, this becomes a cytokine storm showing symptoms of swelling, redness, fatigue, and nausea; even death.

Phytocannabinoids have the ability to suppress this inflammatory cytokine cascade by inhibiting glial cell production of the cytokines interferon or interleukin. Here we see the seeds of chronic inflammation dissolved by the modulation process of cannabinoids bringing homeostasis to systems out of balance. This is a good example of how cannabinoids normalize biological processes all throughout the body and allows us to keep that glow of well-being through a long and happy lifetime. (Bibliography)

-Dennis Hill

Dr Bob Melemede explains further

A comment from the Metro Times Detroit article Pot and the Big “C” (comment section)

I have been researching Rick Simpson’s claims not for almost 2 years — I am happy to report that they are 100% true! I have personally communicated with numerous people who have put their very serious cancers into remission (I do not use the word “cure” because in some cases it has not been 5 years — in some it has been well over 5 years). That research has been stultified on using this plant for cancer and many other ailments IS the crime. The REAL truth — governments had ulterior agendas and they were as malevolent as they could be … pure evil! The bible actually warned that “they” (governments) would, “in later times” try to keep the “plant of renown” away from you … they will be “hypocrites”. It has come to pass and we have to change it because what is happening now is NOT what God wanted for his “plant of renown”.

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See Also:

Cancer Killed by Cannabis

Cure Your Own Cancer dot org

Hemp Oil stories and Testimonials

Does Cannabis cause cancer? Research shows it fights cancer.

433 thoughts on “Biochemist Dennis Hill, who cured his stage 4 prostate cancer with Cannabis oil, explains how it works

    • @Sunil Aggarwal Please provide details….did “prostate cancer” return or was it another form…had the patient stopped using the Rick Simpson oil when the cancer returned. Please provide details..what was the source of your information please. Thanks

      • Hello Dennis
        My query is, were you or have you ever been on anti-androgens during your cannabis treatment ? If you were seeing a urologist this is usually their first line of defence.

        • Over the course of six months of cannabinoid treatment, I had two injections of Lupron, an androgen inhibitor that does not kill cancer. ~Dennis

          • Hi Dennis,

            I believe you said that ceramide deprives cancer cells of ATP, killing them…does that mean cancer patients on the treatment should avoid CoQ10 supplements that increase ATP? thanks.

            • Ryan – Do not avoid CoQ10, it nurtures all cells in the body. THC hitting the CB1 receptor of the cancer cell generates ceramide that causes a rift in the wall of the mitochondria causing ATP production to fail only for the cancer cell. CoQ10 is essential for all cells; ceramide only inhibits ATP in cancer cells and taking CoQ10 does not keep ceramide from doing its job. ~Dennis

              • Dennis–it is a pleasure to hear from you..thanks for writing. Do you have any suggestions on other supplements that would work synergistically w/ cannabis oil? Any to avoid? It is for my dog with hemangiosarcoma. I have her on a wide variety of medicinal mushrooms, colostrum/lactoferrin, billberry, broccoli sprouts, hemp/flax/fish oil, olive leaf, green tea,astragalus, milk thistle, holy basil, bindweed (though have stopped this one).

                • Ryan – from your list it looks like you have everything handled. I have nothing to add to what you already have. ~Dennis

    • Hi Dennis my dad has been diagnosed with stage 4 prostate cancer. My mum and i made a batch up of RSO – using shelite solvent as we live in Australia and obtaning the natural apatha here is very very rare and expensive.He has ingested it for a month now and he sleeps a lot. Recently he has had difficulty with bowel movements and difficulty swallowing. Just wanted to know did you have any similar symptoms and did you take any pain medications whilst ingesting the RSO.. Your info would be much appreciated. Thank you

      • Hi Yvonne – Sorry to hear that your dad has stage 4 PCA. Mine was only stage 3, so I’ve not had the complications you are seeing. Sleep is very healing, and it’s a sign that the RSO is working. Wishing you the best. ~Dennis

      • Hi Yvonne, I too am an Aussie and I’ve got Stage 4 colorectal cancer. I’m having trouble finding Cannabis Oil or Cannabis buds to make the oil. Would you be willing to share information with me?

        • I would appreciate no sales or talk of sales take place on or because of this blog. Please know also that Feds will try to trap you, so responding to calls for help finding a mostly illegal substance can land someone (possibly me) in trouble. This blog is just here to share information, not cannabis.

          One day things will be more free. One day soon :)

          Sent from my iPhone


        • Hi ivone you find oil from mariguana I really need my freind got cancer they be try everythink this is last hope regard carolina

  1. Pingback: Healing Cancer Using Various Alternative Therapies | Cancer Compass ~ An Alternate Route

  2. Sepp: that picture of the new world humming bird dipping into a cannabis flower is the best cannabis picture I’ve ever seen. The humming bird is “bird supreme” and is ultra selective about what it feeds on. This smallest of birds is the king of all birds in the americas, it will drive off anything from its territory, including hawks, ravens, even falcons. Our former apple orchard, now a mega wine industry chemical waste dump, was full of them, amazing animals to observe. Ants are very attracted to flowering cannabis tops for some reason. Writing you from original cannabis culture Japan where use as medicine was ubiquitous prior to WW2. Now it is hysterical paranoia.

    Local monkeys are cruising around outside my window, howling and such (macaque of Japan). I live in the country well south , one would hope, of the nuclear disaster zone.

    Probably a different treatment would be just to vaporize the stuff on a regular basis, or eat the juiced raw flower tops (no psychoactive effect apparently) The distillation method with nasty chemicals requires a very large amount of flower top (legality issues, horticultural issues in terms of difficulty, risk of thefts, etc). topical applications on skin cancers are treated by concentrates, however. Simpson’s extraction method was very primitive, leaving large quantity of toxic waste to be disposed of or evaporated (not good either). Poor guy got screwed badly by authorities, et al.(Simpson)

    Thanks for the gambia news, better than news about the kiddie vaccine for malaria .
    Best regards Neal

  3. Explanation:
    After six months using cannabis extract, a prostate biopsy confirmed the cancer was gone, in February 2010. Twenty months later, biopsy showed cancer had returned. I have reinstated cannabis extract and PSA is declining. I expect the cancer to be gone soon, just as it did previously. ~Dennis Hill

    • Hi Dennis,

      Thank you for this update. My understanding is that Dr. Donald Abrams’ protocol involves a daily maintenance dosage of the oil after the cancer is gone. I wonder if you were aware of that, and if you implemented this or plan to?

      • I knew of Dr. Abram’s maintenance protocol and tried to follow it; however I learned too late that my co-op hash oil had not been decarboxylated. THCA does not fit the CB-1 receptor that is required to send seramide to the work of apoptosis. I will not make that mistake again. After this round of cancer goes away, I will stay with the decarboxylated oil. A very important lesson I have learned.
        ~Dennis Hill

        • Thank you, Dennis – this information is simply invaluable. From my understanding, one rice-grain-sized amount of oil once or twice a day is for treating cancer, is this right? I wonder what size would be for the daily maintenance dose.

          • Rick says start with one rice-grain-sized amount. He also says to increase the dose as you get acclimated. I worked up to two caps in the evening, about 12 grain size. So a maintenance dose might be half or a quarter of that. Say, one cap rather than two. If decarboxylated, this should keep even cancer stem-cells down. I’ll let you know when I find out.

            • “Cap” means a gel-capsule filled with the oil, i assume. So a maintenance dose would be 1 cap filled with from 3-6 rice grains’ worth of *decarboxylated* oil per day (?)

              On a side note, here are two articles regarding solvents used in R.S.oil that readers might find useful:

              Rick Simpson on solvents:

              Interesting thread about using Everclear:

              On a personal note, the reason i made this post, and discovered your story in the first place, is that my good friend received a diagnoses of returned cancer to her breasts. Her doctor wanted them removed within weeks.

              Your story was the most profound and persuasive one that i came across in my search for information about RSO, so I put everything I found together for her. She’s a nurse, so I thought she would particularly like the science you’ve offered us.

              My friend became excited about the potential of RSoil and made a batch. She took it for about two weeks, but decided she was too nervous and went ahead and had a double mastectomy.

              When the doctor removed the tumor, he found that it had reverted to a pre-cancerous state in the few weeks between biopsy and surgery.

              Hopefully we can get a clear protocol laid out so that fewer people have to have body parts removed (and worse). This is the reason i am asking so many questions ;)

              Thank you for your patience, and we all are wishing you the best!

              • Looks like you understand my situation here. But we have to remember that everyone is different in many ways. Tolerances, especially, are variable. The medical cannabis movement is very short on standards about anything, so we experiment a lot out here in the wild. That’s just the way it works, strange as it seems. Thanks for the deeply meaningful story about your friend who took the oil for two weeks. ~Dennis

            • HI Dennis, thanks for all the info on this page. Just wanted to confirm gel caps would be more effective than ‘under the tongue’ or swallowing in on a piece of bread when using the oil for the leptomeningeal & liver metastases. (I’m guessing the caps help prevent the stomach acid effecting the oil).
              Appreciate your time.

        • Hi Dennis
          Are you saying that in order to make rso oil you have to decarboxylate the cannabis before turning it to the oil
          Many thanks

          • Hi, Dennis sent this through email due to tech difficulties :

            Let me put it this way, if you want to use THC therapeutically for cancer, research is clear that the non-acidic form of THC occupies the CB-1 receptor, to trigger the pathway to kill the cancer. If you are not treating cancer, don’t worry about decarboxylation. In any event, decarboxylation can occur at any place in the extraction process, just pay attention to time and temperature. Or try juicing; this works too. ~Dennis

  4. Wow, am I glad to have the uncertainty about Dennis’ treatment cleared up! How did I miss it for nearly 2 weeks? “Update from Dennis Hill” should have been a headline on the weekly news summary. Now can someone get a report from Tommy Chong? I don’t troll all the cannabis blogs, but this one is the best I know of.

  5. Would appreciate it if anyone could confirm whether decarboxylated oil is required in all treatments for cancer? (inc stage 4 secondary liver & bone)

  6. The research I have seen says that the way the immune system (part of the endocannabinoid system [ECS]) naturally identifies cancer cells is through the abnormal DNA. As far as I know, all cancers have abnormal DNA. When cancer is detected, the ECS pairs anandamide to the CB-1 cell receptors which causes the cell to die. Anandamide is mimetic to THC, which also pairs with CB-1 and causes cancer cell death.
    This cannot happen unless the THCA in cannabis has been decarboxlylated; as THCA does not fit the CB-1 receptor, thus no cell death.
    The logic here suggests that decarboxylated cannabis extract should kill all cancers, but of course we don’t know if it is true or not until there has been clinical testing of all cancers treated with decarboxylated cannabis oil. The research suggests that it is THC at CB-1 that kills cancer, not CBD (cannabidiol) at its preferred receptor, CB-2. CBD is wonderfully therapeutic, but I haven’t yet seen demonstration of its mechanism to kill cancer. If it’s out there, somebody please show me. ~Dennis

  7. It is my understanding that only THCA needs to be decarboxylated; in order to fit the receptor CB-1. Cannabidiol fits the CB-2 receptor natively, so no need to cook. Basically THC is THCA with the carboxyl group (a carbon, two oxygens and a hydrogen), liberated by heating. THC fits the CB-1 receptor perfectly, causing cancer cell death, but not THCA. Receptors on the cell wall account for most of the intelligence of a cell. These receptors manage the relationship between the external environment and cell function. Very complex. The Caspase Cascade is activated by cannabidiol through the CB-2 receptor to cause apoptosis in cancer cells. This is a very complex pathway, only recently revealed. So far I see that caspases are cysteine proteases; enzymes that break down polypeptides, ultimately causing apoptosis. That’s the chemistry, but what is really happening at the CB-2 receptor? Does anyone know the pathway that wakes up when CBD hits the receptor? How does that start the cascade? I love a mystery.

  8. Pingback: Prostate stage4 cancer survivor Dennis Hill fights again his recidivism with hash oil. «

  9. What was your PSA when you were in remission and then what did it rise to that prompted the biopsy? My husband says he does not want to go through another biopsy as we are considering all of his options? Also, how did you learn about the fact that the hemp oil that you were formerly taking was not decarboxylated? What dispensary are your currently using to ensure that your oil is not decarboxylated? We live in a state that is has not legalized med mj. My husband says he is not willing to go to prison to save his prostate. Any suggestions on acquiring the purest form of hemp oil with those two caveats would be greatly appreciated.
    Best of health to you!

    • What was your PSA when you were in remission and then what did it rise to that prompted the biopsy?….Remission PSA was 0.1; at biopsy PSA was 1.9.
      what dispensary are you currently using to ensure that your hemp oil is decarbed?….I’m using a legal private co-op, everyone gives work equity, no money changes hands. I know the person who makes the oil. I know the oil is decarboxylated. I watch.

      If you are looking for a dispensary, enter your zip code here:


      • HI Dennis, would appreciate any advice to someone with secondary breast cancer with multiple liver & bone metastases as well as lymphadenopathy in chest & abdomen. We have aquired two different oils without the option to test it. Have been taking it for less than two weeks. No symptoms at all from the cancer. I’m just hoping you may be able to give any advice that you may have picked up during your treatment. It would be great to know which dispensary you used (even though im not in the US). I’d hate to think it doesnt work out because we are using the wrong type of oil or doing something we shouldnt be. THANKYOU

        • I never ever went to a dispensary. My treatment was all home grown and processed. Here is what I have learned about cancer and cannabis: all cancers have abnormal DNA and our endocannabinoid system can heal it. To kill cancer with cannabis extract you have to hit it as hard as you can. Start small, increase doses often, take as much as you can tolerate. Cannabis extract is not harmful to the body; more is better. If you can find it, a strain of THC:CBD=1:1 is best. If you don’t like the effects of THC, use high CBD, that will do it. Both is better, though. This is as simple as I can make it. ~Dennis

          • Dennis, your story is remarkable and brings hope to so many. Just learning about all this for first time as my father is battling cancer. Quick question to make sure I understand…you suggest a 1:1THC:CBD ratio but you also state that it is the THC that is largely responsible for cancer cell death. Rick Simpson also suggests getting as high a THC as possible (suggesting 20% or more). Most of what I’ve seen with THC that high doesn’t have CBDs anywhere close to that %. So, given a choice between a very high THC/low CBD and a more balanced ratio, which do you recommend? (FYI – dad diagnosed with lung cancer 2008. Only had surgery and alternative treatments (not cannabis oil). Cancer has now been found in brain. 2 surgeries, no radiation or chemo. Praying for a miracle) Again, thank you for all of the wonderful information you are providing and helping the rest of us understand this process.

            • Igor – I recommend balanced cannabinoids because they all work synergistically to kill cancer. Many researchers are calling this the “Entourage Effect.” CBD is emerging as a powerful cancer killer, especially paired with THC. ~Dennis

              • Thank you for the reply. Do you recommend using CBD supplements? These seem to be readily available online. Thinking if we go with whatever we have which has high THC but not so high CBD, then perhaps a supplement will help. Concern is we don’t have much time and hard to know (and be choosy) about what you can get. I’m sure getting it all naturally is best, but I’m assuming a supplement can only help. If so, is there anything in particular you can recommend? Again, many thanks.

                • Igor – Supplementing with CBD would be ideal if your primary treatment is THC. ~Dennis

              • Hi Dennis,

                Do you have any thoughts on this product called “herb’s resin” as an alternative to the phoenix tears which here in Vancouver, BC are only made with iso or butane.
                Suggested treatment for someone with cancer is 6 ounces or more. This recipe is for 3 ounces.
                Grind/crush 3 ounces of well-dried top-quality cannabis buds
                Put cannabis in 20 liters of cold water and stir for 15 minutes
                Pour through a strainer or the largest micron size of bubble bag – don’t throw out the buds, stems and leaves yet!
                Let mixture settle 15-30 min. The crystal/trichomes/hash/kief will fall down and settle on the bottom
                Pour/Siphon the water into another pot, leaving the kief mixture behind. Once you pour out most of the water (to about 1/2 inch from the bottom) pour out kief mixture and set aside
                Boil down the water you poured out on mid temperature (7) on the stove burner
                Keep an eye on the water as it reduces and scrape and stir in the oils that form around the sides of the pot.
                Repeat the process with another 20 liters of cold water for a second wash.
                Keep boiling it down to a black, sticky substance – slowly reducing the temp as the water evaporates – don’t burn it. (As the mixture thickens add it to the final reduction sauce pan)
                Take the second batch of water and boil it down too. (I use a separate sauce pan to do the final lower temp reduction in.)
                Put the left over cannabis in another pot with water and boil it too, several times. Add the water to the final reduction pan when it becomes thick like a milky tea.
                Now add the kief mixture you had set aside to the black, sticky pot-water reductions, slowly bringing the temperature down. As the water evaporates take it off the heat and put it back on, that helps to not to burn the resin. The end result is something that looks like very sticky black hash.
                This cannabis resin is water-soluble and can be added back into water to treat burns and heal wounds and be added to teas.

  10. Dennis, was chatting with some medical people about this and one said that cannabis kills brain cells. I know that Rick talks about that adage from the past. Is there evidence to support that comment?

    • If you know so much about what Dennis is doing and Rick has said, then you’re probably smart enough to answer that question yourself instead of bothering him with it.

    • Great question about being on maintenance forever. Two ways to go here; 1) stop cannabis, get PSA every three months. 2) continue maintenance. At this point I’m inclined to continue maintenance. Cannabis is such a great support for the immune system. I’m never sick when I’m taking it. Cannabis is a modulator of wellness in all systems in the body. It’s like the best vitamin you can take to sustain optimum health. There’s no down-side to maintenance. ~Dennis

  11. Scott, you are so right. I don’t want to bother Dennis! I was curious as to what his reponse would be. Also I wasn’t sure if the dosage of hemp oil for cancer would be considered high enough to cause damage. It’s such a shock to hear the diagnosis of cancer and then try to sort through all the conflicting information. I’m not a scientist, just a wife searching for answers for my husband who was diagnosed with cancer about a month ago.

    • Anon,
      Sorry to be curt with you, and many thanks for your sincere explanation. In the climate of fear the government has pushed since the 1930s, it’s easy to get worried–which is exactly what they want.

      The short answer, I believe, is that cannabis is most likely to protect the brain rather than harm it. After all, the feds have a patent on it for exactly that use, as a “neuroprotectant.”. They’ve been hunting for adverse effects for decades and this is what they’ve come up with, not brain damage.

      Rick Simpson appears to live on mega-doses of cannabis–which he takes for brain damage from an accident–and is doing great with it under very stressful circumstances.

      You might want to look at it this way: Cancer causes brain damage (or damage to any other body part it affects). Cannabis appears to stop cancer, and may promote brain healing.

      Best wishes on your search,

      • Thank you Dennis, Scott and the Administrator for you time and help. I believe the oil is worth a try if we can find a way to get through the legal maze because we live in a state where it’s illegal. The residency requirements are “high” hurdles to get over:).

  12. Thank you Scott. There are so many theories, treatments, unscrupulous practitioners/scientist etc. it’s overwhelming in knowing who or what to trust. Science, like anything else can be twisted. This forum gives some comfort, in it’s educational content, and yet for someone new to the idea of using hemp for cancer treatment and without a chem degree, it’s all a little daunting to decipher! It seems like cancer treatment is a “choose your side effects” decion.

  13. Does anyone have any experience of taking the concentrated oil (RSO) in conjunction with chemo ? I mentioned ‘Chinese herbs’ to the oncologist (i didnt want to mention the oil) he went on to tell me about another patient taking something (he didnt say what, but i presume some type of herb) with the chemo that was “very dangerous & caused complications, esp to the liver sas the liver metabolises.. and the.elevated the chemo effect..”. Thats obviously got me very worried. It sounds like it makes sense, the oil is very concentrated, the effect is way more than just smoking a joint.

    Furthermore, i hate to be negative, trying not to be but considering the circumstances, its sometimes hard not to be. But after all the research, getting the oil etc I’ve only ever seen two preclinical trials (one with a mouse and one with a petri dish) that shows the oil getting rid of cancer cells. With everybody else its always a story or a friend. I dont understand why a organisation like,say Phoenix tears doesnt start some kind of kickstarter campaign to raise the funds required where people can anonoymously upload before and after Cat scans, strain of oil, CBD & THC levels, letters from the hospital. Whether they had chemo as well. as the oil. Will this make the evidence more than just ancedotal ? Some kind of structure rather than a short testimonial or a story of a friend.
    I want this oil to work, believe me I do, i think about it everyday (the life of a loved one depnds on it) but I do wonder about this whole ‘Big Pharma’ wont do it arguement. There are many countries out there without big pharma (Cuba, Iran, Bolivia, Venuzula, Argentina). Really, are we saying all these countries are tied into a Big Pharma conspiricy. Surely, say Cuba, would have researched it, proved, bottled it and exported it globally by now. They would make a mint (not everybody can grow and make it themselves, plus it would have some kind of consistency. In a similar way we buy beer rather than grow the hops and ferment it etc).

    • Regarding the PhoenixTears idea–are you ready to upload your medical information to the internet? Rick Simpson is practically a stateless person now that he’s challenged Canada so forcefully. He’s been raided by the Mounties three times, and in a personal email to me he said they seized all his records. (I don’t expect that Rick kept the most rigorous medical records anyway, but how much can or should one man do? He’s done his huge part.)

      “There are many countries out there without big pharma (Cuba, Iran, Bolivia, Venuzula, Argentina).”

      I’ve had the same question, but it might take a social psychologist/political scientist/philosopher and a lot of research to give a good explanation. Here are my ideas:

      Don’t expect a burst of enlightened rationality just outside our borders–or anywhere. Basically medicine in 3rd world countries is going to follow 1st world examples in science, if not in economic rationing (provision of medical care). Techno-science is dazzling to them, just as it is to us.

      Repressive regimes of any stripe oppose recreational drug use. The last I heard, Iran had the death penalty for some illegal drugs. Dubai or Bahrain was sentencing travelers passing through their airport to several years in jail for the tiniest possible flakes of herb. In the case I heard of, the minuscule amount of MJ was caught in the tread of a shoe. I think the reasons for such repression are psychological, deeply embedded in the unconscious, and institutionalized in laws. Wilhelm Reich may have identified that long ago.

      Countries with the slightest friendly inclinations toward the U.S. are strong-armed by U.S. drug policy enacted through the U.N. as well as direct inter-country treaties. Now the U.N. is even returning the favor by protesting that two of our states have legalized marijuana use.

      Many dictators and others are on the U.S. military dole. They don’t want to piss off their supplier.

      The U.S. would be happy to allege that Cuba or other enemies are running drugs into this country. I’m sure the allegation has been made. Cuba would not want to give any credence to such stories. And who would they sell to?

      Doctors in those countries may want to escape, emigrate, or even just train here. You won’t find them challenging U.S. drug policy. Third world countries are deeply aware of their shortcomings compared to us–they don’t want another reason to risk ridicule.

      In 1995 I personally funded the visit here of a Russian M.D. who was experimenting with ketamine at psychedelic doses to treat alcoholism, but he was careful to try to fit his research into acceptable U.S. paradigms. He chose ketamine to work with because it has accepted medical uses, rather than using herbal psychedelics–although they probably weren’t available in Russia anyway. He ended up with a fellowship to spend a research year at Yale.

      Look instead to 1st world countries with more liberal attitudes. Holland doesn’t just have hashish in coffee shops; I’ve seen videos of patients being prescribed cannabis and getting their scripts filled. England and Canada are growing cannabis and marketing a new cannabis drug, Sativex. Important research is being done in Spain, Italy, and Israel. Portugal has decriminalized all drugs.

      It takes time…and people willing to push the envelope.

      • Hi Scott,
        Thanks for your detailed and thoughful reply.
        With regards to the uploading personal medical files. I would certainly upload them withholding personal information. I would also probably use software to hide upload location. However, I do agree that piling all this responsibility on one person is not fair.

        I agree with your points of why these other countries have not investigated the possibilties. You raise a variety of interesting points that seem to ring true. However, I’m sure if money was raised by ‘the people’ using various crowdsourcing sites it be more likely a non aligned country will allow research in there country.

        Sativex is certainly progress (even though its very difficult to get a prescription) and they certainly wont prescribe to cancer patients.

        Scott, you clearly knowledgeable in this area so i would like to ask you a question. I’ve read that some mention the CBD percentage is important and others say its a high THC percentage thats important. I would appreciate it if you cold let me know your thoughts on what yuo think the optimum percentages are.

        Many Thanks

        • My question about uploading personal medical information was rhetorical–designed to let you answer your own question about why you don’t see more medical data from users on the web.

          Regarding THC:CBD ratios–I don’t have any idea, but I have probably seen some of the same speculation as you. If I were in a position to need the treatment, I’d try just about anything I could get my hands on.


  14. I thought I posted this but don’t see it so will re-post. Thank you all for your thoughts and support! Dennis, may your recovery be speedy and permanent! You are an inspiration and kind heart.
    Hemp oil is a direction we would like to take. However, we have to find a way to navigate the residency requirements and legal issues while living in a prohibited state. So far, I’ve not had time to find a viable way around it. Any suggestions are welcomed! Anon

  15. Hi Dennis, just wanted to say that you are an inspiration to me. Been diagnosed with a very rear cancer last year. Been on oil for de past 4 months, with a break of 3-4 days each month. The thing I want to mention is the fact that I cannot take more than 0.2 gramms a day. I get really stoned. Just don’t know how come people take 1 gram per day. I bought my oil from Amsterdam.(I live in Europe)
    My question to you is: do you think that the small amount I am taking will destroy my cancer or I should try to increase the daily dose?
    Thank you!

  16. Hi Dennis,
    First of all thank you for answering my question.
    I will try to find out the exactly % of thc and cbd and will let you know. You mention above about the oil being decarboxylated. I have no idea how it is but will also try to find out. The only problem would be that I don’t know another supplier here in Europe.
    My regards,

  17. Hello Dennis,
    Hope you are well…..and good for you for taking medicine into
    your hands….before others…

    We have a dear friend whose PSA is rising quickly….his prostate
    cancer has returned after 5 years….he is looking at alternative
    therapies….he is done with the usual cut..poison…and burn..
    His PSA is only .25 but will soon get to 1.0 or 2.0 per his
    oncologist….. should he decide to use the Rick Simpson protocol
    would he still need 60 grams over 90 days…. or could he get by
    with less…..he’s not a pot user …. and is worried he would be stoned all day……

    • A PSA of 0.25 is very low. Abnormal starts about 4.0. It will be up to the patient whether he starts alternative treatment. He should research the available literature and decide if this is what he wants to do. There is certainly no harm in trying the cannabinoid route. If he doesn’t like being stoned, then he should investigate CBD as the therapeutic agent. My sincerest wishes for a rapid recovery. ~Dennis

  18. Hi Dennis,
    Thanks for your response….
    He has decided to go the Rick Simpson route…

    Since his PSA is low…. .25 do you think a protocol of 30 grams…over the course of two months would be sufficient to knock down his PSA to .01 or less…? and from what he has read and seen….he believes this can be done ….he’s changed his diet…become a vegetarian…and his lifestyle… is starting to
    meditate….and take up yoga….

    he has no problem being stoned daily for a few months…if he can get his PSA down and keep it down….assuming all goes well..
    what do think would be an appropriate maintenance dose…..?

    Also he has been taking vitamin B17… from the seeds in apples
    and apricot pits…any harm in continuing….. or is it wise to stop..?

    Keep up your good work !!

    Your story has most definately inspired him…to change his life..
    for the better…

    Regards…… a friend of Gord,


    • You can follow Rick Simpson instructions, I have nothing to add to that. If Gord has had good results with B-17, it should be okay to continue. Use common sense plus your best information.

    • Dew drops hemp oil supplement is CBD.under. 3% THC.That’s why it is legal to ship. If you have a severe problem go with stronger solution. Ive been taking this for a month for my chronic candida I have had for 28 years. Its a game changer. Gives pain relief mental clarity and focus and general happy feeling without stoned.and shows great results for cancer Ms Alzheimer’s etc.!

  19. my husband has prostate cancer and we are in a prohibited state. Does the Dew drop meet all the criteria as prescribed by Rick Simpson, decarboxylated and potency? Thank you so very much!

  20. Dixie dew drops is CBD concentrate. Rick Simpson oil is high thc concentrate. Totally different type of product. Both seem to be effective but dew drops can be shipped to all 50 States which makes them good for many people in non medical marijuana States. Maybe I have confused matters by bringing it up on this site but I feel its very important info

  21. Dear Dennis, Admin, or Tim: it looks like the CBD from Dixie Dew Drops is a viable option. They also have capsules. Can you provide some guildance on doseage for either the drops or capsules? I know what RSO suggested dosage is but have no idea with these products. Thank you so much! Anon

  22. Dear Dennis, Admin, or Tim: CBD from Dixie Dew Drops looks like a viable option. They also have capsules. Can you provide some guildance on doseage for either the drops or capsules? I know what RSO suggested dosage is but have no idea with these products. Thank you so much! Anon

    • Anon,
      I’m going to be blunt. I have 20 years experience working with the legal ramifications of cannabis. You may be completely sincere, but your questions remind me of an undercover police officer trying to set someone up. You have essentially all the information that anyone else here does, and certainly more than enough to start finding your own answers. Why don’t you come back when you have some information for us?

      • Hi Scott, I understand your comment and appreciate your concern. I am not an undercover cop. My husband has prostate cancer and I am trying to find answers for him. I thought that perhaps someone could advise on the CBD as it is different from the THC. I don’t want to make mistakes as we are fighting time. I don’t know how to convince you unless I post his lab findings. I wish I was a cop trying to bust people rather than a wife who is looking for answers. I apologize if I’m asking inappropriate questions on this forum but thought that there were scientists here who could advise. Because CBD is legal to ship I didn’t think that it was an inappropriate question. I would be willing to speak with you if there was a way to not have my personal information on the internet forever. Thank you. Anon

        • If you are fighting time, then why are you waiting to do something? I see plenty of answers already on this forum. Questions are a poor substitute for action. If you want more information, find a doctor who is a member of the Society of Cannabis Clinicians. Most anyone else who tried to answer your questions would end up endangering themselves.

        • Scott. I appreciate your answers. I just learned of hemp/CBD about a month ago as well as the diagnosis of cancer. I’ve been trying to gather as much legitimate information as rapidly as possible. This seems like the most reliable site I’ve found on the internet. It’s all overwhelming. I thank you for your time. I would never want to put anyone in harm’s way! I am not trying to cause any problems. I will look at your link. Again, THANK YOU!

        • Scott, thanks for the nudge. Ordered from Dixie Dew Drops. Went with the capsules. Hope it works. A friend of ours just had surgery from prostate cancer and it did not go well. We really want to avoid the cut and burn methods! Thank you again!

        • This is the ugly result of cannabis prohibition. It has to be said. It is just so sad that we can’t speak freely about healing cancer with an herb. It is a violation of human rights to put fear into the hearts of the suffering, and those coming to their aid. Hopefully soon this medicine will be available as will good information about how to use it.

          As for CBD, there has been science showing it stops the growth of cancer cells. I have no idea what amount one would have to take to get those results, if at all. They haven’t started human trials yet.

          Basically, from what I understand, it takes high doses of cannabinoids to heal cancer. I don’t know how that translates when you’re talking about CBD pills. All of this “we don’t know” is due to prohibition. The government literally won’t allow scientists to do the research.

          Blessings to you.

        • If I had cancer, then I’d be looking for the most pure RICK SIMPSON OIL (RSO) available! (95% THC or better!!!) Then I’d administer the oil according to Rick Simpson’s suggestions and let the healing begin. Anything less for me, my friends and family is unacceptable. If you want to cure CANCER…why mess around with the less potent oil? Good luck with the other oils ;-) PEACE!

        • To John W: I appreciate your advice about getting the best treatment possible for cancer. We are law abiding citizens and the fear of going to prison outweighs the fear of allopathic medicine for my husband. The best plan I’ve been able to come up with in a month is the CBD capsules. I read the post with Nathan Kisper’s name and after reading the post about me being an undercover cop I’m even more frightened. I know of people who have been imprisoned for drugs and that’s a battle I don’t want on top of the cancer fight. I am very open to suggestions however! Anon

          • Warning – There is someone who speaks broken english, who is spamming this site with talk about some doctor’s ‘special’ hemp oil.

            I erase every comment from them and block their IP, but they keep coming back.

            When asked where the doctor is licensed, one is told you need an attorney to get that information!

            This is a SCAM.

            Preying on people who are sick will NOT be tolerated -

            • CONGRATULATIONS!!! You saved your life! You KILLED the cancer with the oil. Cannabis has been used for health and healing for more than 12 thousand years, documented. The doctor was simply a conduit, channel , for your healing process. The PLANT is the DEITY here. Your doctor is STELLAR for recommending the oil. I produce my own Rick Simpson Oil following Rick Simpsons method religiously! I’m just curious to know what were the levels of THC/CBDs/CBNs that your medicine contained to effect the healing you received. THAT is what will help us to accrue the necessary data to enhance our desire to help heal ourselves and others. THANKS SO MUCH! WE ARE ONE!

  23. I found 89% thc oil – is that good enough to help my mom with stage 4 cancer? I know you say 95% or higher but it’s very difficult to find if you don’t live in a legal state. Should I plan to give her more than 60 grams? She’s only a couple of days into it at this point.

    • I seem to recall that someone said 92-93% oil is the minimal THC for curing cancer according to the 60/90 suggestion. Again, that’s what I recall hearing. Please don’t use this as your final… but I do recall the discussion and numbers. PEACE!

            • Our strain was White Fire OG Kush which tested at 95.51%THC (the highest ever tested at Greenleaf Laboratories here in Portland, Oregon [out of >100K tests] and the CBDs at 1.54% and the CBNs at 2.06%. We were surprised too. We follow Rick Simpson’s protocols 100% to get these results. If you’re using ethanol to process the bud material, then THAT might be the problem. Some solvents remove too much of the extraneous components (turpentines/chlorophyll etc) which then contaminates the oil…(the oil will appear BLACK when smeared over a piece of white paper) which should appear a clear amber color when smeared over a piece of white paper. The oil I produce is “Rick Simpson Oil” and not any other name :-) I will be very happy to tell you exactly how I made the oil, or you can get your own copy of Rick Simpson’s book..either way..RSO works! PERIOD! PEACE!

        • Hi I have been doing a lot of research latley on different strains
          And found this seed ,Medicann Seeds ,Blue Blood 20%thc10% cbd
          Would this be a good choice for making rso
          Cheers gary

  24. Hi Dennis,
    I am currently on Day#42 of a 90 Day ‘quest’ to kill my prostate cancer. I was diagnozed (bioposy) in March 2005. My Geason was 6 and stage 3, My urologist —plus a ulologist from Mayo Clinic in Rochester, Mn recommended that I have surgery. I decided NOT to do surgery, but instead began to investigate a number of alternative treatments. So far, I’ve managed to survive , athough My PSA has steadyily increased over the couse of the 8 years. It is now 21.9. I started at 5.7 eight years ago.
    I am a retired science teacher who will soon turn 63 years old.Grandchild #9 just arrived form me yesterday morning (2:38AM).
    I hope to have a ‘story’ of my own to tell. I hope we might have a chance to meet/talk some day soon. I might even consider flying/driving out sometime soon.


    • Hi Rod – if you would like to try the cannabis extract for treating your cancer, follow directions given by Rick Simpson “Run from the Cure” video. Most folks I know of have had good results. ~Dennis

  25. Pingback: Biochemist Dennis Hill cured his stage 4 prostate cancer with … | How to Make Butane Honey Oil - BHO Guides & Information

  26. Reblogged this on Bloom Room SF Blog and commented:
    “In 2006, researchers in Italy showed the specifics of how Cannabidiol (CBD) kills cancer. When CBD pairs with the cancer cell receptor CB-2 it stimulates what is known as the Caspase Cascade, that kills the cancer cell. First, let’s look at the nomenclature, then to how Caspase kills cancer. Caspase in an aggregate term for all cysteine-aspartic proteases. The protease part of this term comes from prote (from protein) and -ase (destroyer). Thus the caspases break down proteins and peptides in the moribund cell. This becomes obvious when we see caspase-3 referred to as the executioner. In the pathway of apoptosis, other caspases are brought in to complete the cascade.9

    Even when the cascade is done and all the cancer is gone, CBD is still at work healing the body. Its pairing at CB-2 also shuts down the Id-1 gene; a gene that allows metastatic lesions to form. Fundamentally this means that treatment with cannabinoids not only kills cancer through numerous simultaneous pathways, but prevents metastasis. What’s not to like. One researcher says this: CBD represents the first nontoxic exogenous agent that can significantly decrease Id-1 expression in metastatic carcinoma leading to the down-regulation of tumor aggressiveness.10″

  27. i live in Ireland and have early stage prostate cancer, can you let me know where i can buy the oil that has been decarboxylated, i seem only to be able to buy hemp oil at the grocery store and its not the proper one. I would be so thankfull of any help you can give me.


    • Charles,
      The first thing you need to do it watch Rick Simpson’s video, “Run From the Cure” which is all over YouTube, and upon which all this blogging about cancer treatment is based. Everything after that will rely on your own initiative. It will be vastly easier for you if you live in an area which allows medical marijuana. Anywhere else, you can be sure that it’s illegal.
      Good luck, and please post your medical results/experiences if you try it.

    • Debra,
      Anyone answering your question is in effect engaging in a conspiracy to violate federal law, and becomes chargeable with a federal crime if you should act on that information–and perhaps even if you don’t. I’d have to check the law, and no one’s paying me to do that. But I’ve seen it used several times to convict people who had no direct involvement in the actual “crime” which later took place.

      Still, there are so many potential violations and law breakers out there that the feds can’t begin to catch or even worry about them all, so the internet is running wild with information. For instance, all the medical marijuana shops operating openly in states that allow them are committing federal crimes–and they are brick and mortar establishments much more permanent than posts on this blog.

      But I have strongly advised this blog not to allow informational exchanges about actually obtaining medicine being posted for fear that the blog itself then becomes liable for the actions of its readers.

      So the short answer is no answer at all. But you can find it if you keep looking. Read the stories of others who have done it.

      Good luck, and don’t make yourself a big target.

  28. My first basal cell carcinoma appeared over 30 years ago under my right eye. The dermatologist cut it out and radiated it. Over 100 other basal and squamous cell cancers have been treated since.

    Several years ago, a tenacious cancer appeared within my ear. The dermatologist treated it many times before a Mohs surgeon removed it’s top.

    In 2005, the proctologist found cancer in six of nine prostate biopsies.  But the aorta valve in my heart was replaced first due to a heart murmur.  Then I received 43 prostate radiations.

    As I recovered from the open-heart surgery, I lost the central vision of my right eye. The heart surgeon told me a tiny bit of plaque most likely got loose as a result of the aorta surgery, causing a central retinal artery occlusion. A vascular surgeon then cleaned my right carotid in case it was the source of plaque.

    In 2010, a full-body Scan showed tumors in the center lobe of my right lung. Biopsies indicated adenocarcinoma. The pulmonologist, oncologist and thoracic surgeon agreed the gold standard of treatment was removal of that lobe.

    After several more scans showed the tumors were growing, and after viewing the complexity of lobe removal (http://, I chose radiation treatment, thinking I’d have a better chance of surviving than going under the knife again.   24 radiations and 12 more scans confirmed the lobe was well zapped.

    In the Fall of 2011, cancers were appearing in other lobes and another skin cancer was removed from the back of my ear.  I was in between the scans scheduled to see when and where the next zapping would be done.   Thankfully, a friend suggested I watch Rick Simpson’s internet film “RUN FROM THE CURE”.   After watching, I thought “what have I got to lose”?

    I got a Michigan Medical Marihuana license that November and made some cannabis oil.   As I consumed the suggested dose by April, I was able to function normally.   My children were unaware of my treatment until we told them in March.  No “joint” smoking was involved.

    Recent CT scans, X rays, Echo Cardiograms, EKG’s, carotid and aorta scans, blood tests, heart monitor test, and physical exams indicated I am free of cancer. Occasional skin cancers are now treated with the oil as they appear.   I’m in my 80′s now and thankful to Jesus that I am again able to enjoy prayer, golf, scuba diving, racquetball and water skiing.

    Obviously, I don’t know how this will all turn out.  But I am reminded of Rick Simpson’s statement that the “healing powers of cannabis oil do not stop at cancer”.  He said he not seen any disease that cannabis oil couldn’t cure, including cardiovascular disease, diabetes, Crohn’s disease, arthritis, multiple sclerosis, pain disorders, mental disorders, etc.

    Over-dose of many medicines, even aspirin, can be fatal.  If one takes too much cannabis oil, the effect wears off quickly and no harm is done. I have not heard of anyone dying from its use. I have also verified that it is no more addictive than the daily baby aspirin I used to take.

    What if Cannabis Cured Cancer: Full Version – YouTube - 49′

    Run From The Cure The Rick Simpson Story (Full Version) – YouTube -58

    Shona Banda’s interview show cannabis treats more than just cancer and that very little is needed to produce remarkable results: - 3′

  29. Good morning sir.
    Thank you for your job.
    I’ve tried RSO for 6 months with my own production (good quality i think) My Psa went from 14 to 18.. (T2 minimum)…and now, the cancer went through the apex….now, i have to be very carreful….6 month was maybe not enough, or i didn’t took enough, i dont know….If you have an idea and time to tell it to me, it would be a great help.Thank you.

  30. To kill cancer you have to hit it very hard with high potency, decarboxylated THC. If you did this, then I would expect better recovery.

    • Hello Dennis
      My name is Paul and I live in Santa Barbara, California. In December 2011, I was diagnosed with stage four metastatic prostate cancer. Cancer cells had migrated to my pelvic bone. I was on Lupron and Casodex for sixteen months until that therapy (hormone replacement) became ineffective. My PSA jumped from near zero to eight in three months. (A recently expected one month jump from six to twelve, referred to by oncologists as doubling time, was apparently slowed by an aggressive use of Chinese herbs, an alternative therapy I have been using for almost eight weeks). We are now in a period of “watchful waiting”, but traditional chemotherapy, probably Taxotere, seems to be the next course of action.

      I have recently read various on-line sites and watched numerous videos by and about you and Rick Simpson, and the apparent benefits to be derived from RS oil. Last week I applied for and received a California Medical Marijuana card. I am now using a product called “high CBD oil” (said to be 35% CBD / 35% THC). Because of it’s viscosity, I have been inhaling the fumes with the aid of a small pen-like vaporizer. I would prefer to take the medicine orally (easier on the lungs), and preferably an oil closer in composition to RS oil.

      I sent an email to Rick Simpson, but as you know, he is currently unable to direct me to a source/producer of the medicine. (Emails are “returned to sender”). I contacted a source in Canada, but their product is essentially Cannabis oil (high in THC and quite low in CBD). A lab/source in the Netherlands that looked quite promising on their web site said they were unable to help me.

      Can you suggest a source where I might obtain this oil?


      • Paul – you could put the “high CBD oil” in a capsule (via food syringe) or enema, instead of smoking. To get RSO you might find a distributor here:
        Good that you are in a legal state and have your card now. You should get very good results from high CBD oil. Take as much as tolerable to kill the cancer. ~Dennis

  31. My father has been recently ( a week ago) found that he has a prostate cancer were can we find this Madison called cannabis oil in south Africa

  32. Hope is coming back, T.Y.
    The point now is that they don’t want to remove the prostate, but check tne ganglions via a robot, then radiotherapy plus hormontherapy on a three years period.

  33. anyone know if smoking extra production (i mean a lot) could brake or stop the rick’ cure? thank you for big help, for now, i’m lucky that the cancer didn’t went to the bone (metatstase) feel so stupid ,…

  34. Is there any hope for my husband with 900psa? I take the “oil” to him at the care home twice a day. He grows weaker by the day.

    • Wonderful that you take the oil daily to your husband. It always helps in some way, and is never harmful. This is a very sweet way to care for him. Perhaps we cannot know the outcome, but the caring is very important. ~Dennis

  35. Dennis Hill has stated that it is very important to make sure the cannabis oil is “decarboxylated”. Does this take place automatically if the oil is processed according to the instructions on the phoenix tears site? From Dennis’ instructions on this site it would appear that the dried material must be first placed in the oven at around 240 degrees F for 30-45 minutes after going through a blender. Then after that one would go about making the oil as per Rick Simpson’s directions? Our Vita Mix blender would just make powder out of it.

    • I would think that distilling off the solvent from the oil would automatically decarboxylate it, but because Dennis Hill experienced some oil that wasn’t decarbo-ed, then maybe it doesn’t. What temperature is the solvent is being cooked off at?

        • If you plan to use the Rick Simpson method, make sure that the plant mass (or the extract) cooks for 30-45 minutes at 260º F. Some may think they follow Rick’s instructions, but if they do not know the importance of decarboxylation for cancer, it might get overlooked. If you use cannabis extract to kill cancer, use what ever method you like, but don’t neglect burning off the carboxyl group from THC and CBD.


        • “When cooker is turned on, thermal sensor will monitor cooking temperature. As water boil at 212 deg F so cooker will have temperature not higher than 212 F while rice is still wet with water. Immediately after water dry up, cooker temperature will rise above 212 F so cooker will turn off.” … “Some rice cooker has warming function. After rice is cooked and power is off, cooker still give some heat to cooked rice keeping it warm. This temperature normally about 150 F which will keep all microscopic activity at minimum, also will keep rice soft.” –

          Rice cookers- a la the Simpson Method, only get as hot as the boiling point of the substance they are heating, since evaporation keeps the temperature from rising higher. Thus water evaporates at 212 deg F, so as noted above, rice cookers can’t heat the water any higher than that. Isopropyl alcohol evaporates at 180 deg. F. 190-proof Everclear boils at 173 deg F. Common naptha (VM&P) is a mixture which boils in a wide range from 68 to 167 deg F.

          Conclusion: It appears that none of these solvents would boil hot enough to reliably decarboxylate THCA to THC.

        • RE: Clarifying the process of making RSO
          The rice cooker and hot plate method which Rick Simpsons suggests using are both limited electronically to never exceed the maximum temperate that the oil ought never exceed during the cooking process, which I recall to be approx 295º

          My validations have indicated that the oil in a standard 4 quart rice cooker usually hovers around 260º -280º at it’s hottest point in the distillation process. I validated the temperature with a a meat thermometer, a candy thermometer and a digital multimeter with a temperature probe/gauge.

          The remaining steps in the process have to do with distillates, timing and temperature. Rick Simpson suggest using either of three distillates; 1) Ether – 2) 99% Isopropyl Alcohol – 3) Naphtha

          Which either of the 3 is accessible/useful to you, take your pick

          Locating a knowledgeable grower and/or gearing up to grow your own medical grade cannabis is a major step in the right direction. Rick Simpson suggest using “quality bud material” to get the best quality/grade of medicine that works best for treating most serious cancers (high THC/CBD levels) The quality of medicine produced is related to the particular strain, cultivation and curing methodologies. All the information one needs to produce RSO is in Rick’s book, “The Phoenix Tears” which can be obtained from the Phoenix Tears Foundation at the following link :-)

          I’ve made about 20 batches so far (using ≈25 pounds of quality bud material) and I’m seeing all the evidence a person needs to see that Rick Simpson Oil “REALLY” works! The reason for all the fuss about RSO -vs- any “other” cannabis oil has to do with the ratios of the usable components of the oil one gets when the cannabis is properly cooked (decarboxylated), which is the beauty of the RSO method. It’s simple to produce for a minimal costs…as long as one can grow or locate quality bud material and the distillates readily. Rick Simpsons process is tried, true and tested ;-) Simply following Rick’s method precisely using one of the aforementioned distillates will obtain the desirable yield of pure RSO :-) Hope this helps a little. GET THE BOOK ON RSO from Rick…it’s easily obtainable online at ;-)

  36. Dear Dennis, I wrote to you a while ago mentioning my husband’s PSA 900. His abdominal region is swelling which I understand to be swelling of the liver. We are planning on bringing him home to manage possible larger doses of the “oil” at night when he won’t know how drunk he feels, which his problem has been each Time I make him a rice grain dose wrapped in bread to make a pill. Have you EVER heard of anyone that far along with prostate cancer heal? You can be truthful with me. I can take it. Thank you so so much for your quick response last time.

    • 900 PSA is pretty high, but cannabinoid extract can still help. As he gets accustomed to the extract effects he can take more. During my treatment I took a large dose PM and small dose AM, which allowed me to work and drive.

  37. Hi Dennis,

    Charles leaves this comment:

    Hi Dennis….

    So glad to see that this medicine
    does work….

    We managed to acquire the oil..
    all through the proper legal channels..

    My friend… Started with .02 grams on
    March 1/13….. and over 3 weeks
    gradually increased his daily oil intake..
    up to .50 gram by weight daily….
    and since the last week he is able
    to take a total daily dose of about 1.0
    gram…the oil is of good quality….

    A gas chromatograph indicated
    THC purity at 85.15%
    CBD purity at 2.01 %

    He has injested a total of about 18.0
    grams of RSO …..since March 1/13…

    We are very optimistic… that this
    medicine will slow down his PSA…

    We have changed his diet…. He exercises
    As much as possible… Is juicing…
    cut out the red meat… no dairy…
    lots of salads fruits and veggies…

    His Gleason score was 9… Stage 3
    Clear margins…. But spread to
    the lymph nodes…. Is micro metastatic

    We plan on continuing at 1.0 gram daily..
    until his cancer is gone….

    Any comments or suggestions…


    • Once again, if you are killing cancer, it’s more potent if you start with 1:1 THC:CBD, as we know that CBD is effect at stopping the spread of the tumor.

      • @Dennis Last month I produced one batch of RSO from a strain that came out 38.85% CBD 54.95% THC and 4%CBN … that is close, but still not a 1:1 ration… More recently I produced a batch that is 9.03% CBD, 81.43 THC and 5.96 CBN as tested by Green Leaf labs here in Portland, OR. Do you have any suggestions about how to easily obtain a 1:1 ratio for cancer patients. Are there some symptoms which may benefit from higher THC rations to CBD ratios? I admit that I know very little (electronics engineer here, no bio-chemist ;-) but am teachable and truly intend to help cancer patients because I CARE! If there is a better way to treat cancer patients, then I think they deserve to have untethered access to that treatment…and so do we who intend to help them. Thanks Brother Dennis. PEACE!

        • Hey, 38% CBD and 55% THC is close enough to 1:1; doesn’t have to be exactly 1:1. Just need to have CBD for control of metastasis. This is the basics, if you do this, there will be success. All cancer patients benefit from THC primarily to generate Ceramide to shred the mitochondria which starves the cancer cell. Next, you just have to keep it from coming back, with CBD.

          • I had one batch come out 95.51% THC, 1.52 CBD and 2.65 CBNs and am actually using some of that oil presently. Do you think that for my chronic pain issues/seizures that I would be better off medicinally to stick with the high CBD varieties instead of the high THC strains that all the stoners insist on? I’m still researching but appreciate some good advice on the main medicinal components of he cannabis plant and what each component is good for. PEACE!

            • I think you will need to experiment with various combinations to know for sure; but from what you describe, I think the 1:1 would serve well.

  38. @Dennis
    Could you please indicate if the material has to be dry before putting it in the oven to be decarboxylate or if we cut it and place it right in the oven, and this will make it dry.
    Thank you ;
    May your work receive the blessing it deserve.

    • I recommend that you dry the plant material first (hang it on a rack), before decarboxylation. But you should experiment and see what works best for you. ~Dennis

  39. Thank you again for theses pages and time for answering, I will do the same as soon as i’m finish with this cancer, maybe by translating some pages in French….

    • I do hope you get to do some translation, so that your countrymen (and women) have this information about treating cancer with cannabinoids. I like it a lot better than chemo and radiation.

  40. Dennis, thanks a lot for the scientific background information you have provided. As well for your patience and time to answer all these questions. Here is my question. : Was there ever a moment that starting up with the very small dosis of the rick Simpson recipe oil that you got distracted in your day to day job and felt that you could not work because you were getting hi? or is it true that the starting with the very small dosis results is no high at all and that one might expect just to stay functional at ones job?. maarten

    • Maarten – if you are taking cannabinoid extract for cancer, best if you start small and increase as you build tolerance. THC gets you high, that is just the way it is. If you don’t want to get high, choose a different therapy. If you are not treating cancer, try CBD. That doesn’t get you high. If you take such a small dose that you don’t get high, then you are likely not getting enough to be therapeutic. This is the cost of using cannabis extract therapeutically. During my therapy I took a small dose during the day so I could drive and work. Then a large dose before bed, and just sleep through it. Best of luck to you. ~Dennis

    • If you come to Oregon, we can help you to obtain your Oregon Medical Marijuana Program “patient/caregiver/grower” cards to use, administer and grow medical cannabis. Then you can either grow your own cannabis and make your own RSO or if you are sick and cannot provide for yourself, then you may appoint another person to grow/provide your medical cannabis for/to you :-)

      If you are in another country besides the USA, then unfortunately we can NOT help you here in Oregon. However, if you are from ANY other state in the USA, “Oregon cares,” and we can and will help you. All you provide is a legal ID showing that you are a US Citizen along with any doctor’s statement and/or chart notes indicating a qualifying condition and then The Hemp and Cannabis Foundation (THCF) here in Oregon will be happy to help you to obtain legal access to the medicine which you require.

      I would say that if you are from another country and you make it to Oregon, you are home… just look for clouds of smoke and lot of very happy people…at least those if us whom partake in the TREE OF LIFE …. ;-)

      • Hi John & Dennis

        Hoping you may be able to help with a question:

        1. This CBD/THC ratio is causing some confusion. I dont think there is a case (ie anecdotal) online I can find (apart from yourself (Dennis)) that suggests a 1:1 ratio. RSO doesnt mention it and I suspect a majority have approx 55%THC and <1% cbd. Do either of you happen to know of other people where the oil has helped reduce tumours and what concentrations they used ?

  41. I don’t know anyone else; but the reason I recommend 1:1 is that we know THC kills cancer, but we also know the cancer can come back. CBD is known to inhibit metastasis, so it only makes sense to inhibit the cancer return. Do you think I am right about this? ~Dennis

    • We know of a local patient here, Cindy, who had a tumor that was making her blind and here headaches were murderous! After a couple of weeks of using a high THC “and” high CBD oil made per Rick Simpson’s method, Cindy experienced a remarkably fast from a near fatal situation. Cindy continues to improve. Her latest MRI 6 months later cannot detect a tumor at all where once “golf-ball-split-in-half” sized tumors had once resided behind Cindy’s eyes, threatening her life. Cindy’s story will be told more fully by Cindy herself in the coming months :-)

      • Hello John & Dennis,

        My name is Pete and have a very rare type of cancer.
        Regarding Cindy, would you be able to provide me with more information about the oil she’s been taking and the name of the tumour she had!
        John, you are saying that she used a high thc ‘and’ high cbd oil! What is that mean? What are the procentaj of thc and cbd used.
        Also i am asking about the name of her tumour because mine is located more or less in the same aria, under the skull base, not far from optical nerve.
        Thank you in advance!

        Sent from my iPhone

      • Excellent news. we really need a wordpress site where we can upload anecdotal evidence in an organised format:


        Strain, ratios, amount, time taken for response, type of chemo (if any) etc

    • I dont know. So I guess I’ll be trying both ratios. The best I can find at the moment is 4:1.
      I’m leaning towards your CBD point due to the article below article from reputable Nature magazine (refer to page 7, middle column, first paragraph).

      • …sorry, i cannot paste links. You can search for “Towards the use of cannabinoids as antitumour agents” its by Guillermo Velasco, Cristina Sánchez and Manuel Guzmán

        • I also found this on page 4 of the same nature article:
          “It is worth noting that CBD, by acting
          independently of CB1 and CB2 receptors,
          produces an antitumour effect — including,
          the reduction of invasiveness and mestastasis
          — in different animal models of cancer
          (Supplementary information S1 (table)).
          This effect of CBD seems to at least partly
          rely on the downregulation of the helix–
          loop–helix transcription factor inhibitor of
          DNA binding 1 (ID1)58,59.”

  42. Hello Dennis and John, I was able to make the oil my self to begin my treatment last week at terrific expense and after taking a small amount in the evening I had difficulty speaking clearly the next day felt total paranoia was difficult to sleep, this is a problem as if this is the case I cannot work and support my family if I cant speak. i think I have the high thc medical grade stuff. Is it possible that it is just too strong, is it possible that I could get used to this so that I can function he next day after a while, I am so very upset and disappointed, I do not know where to go now. Any advice would help here.

    • Jim, do not give up on this. Just adjust your dose small enough that you sleep deeply and wake up refreshed. You will build tolerance as you go along, just add increments to the small amount. I started the same as you; remembering waking up at night and could only crawl to the bathroom. Eventually the tolerance will build up, you will be able to take small amounts during the day and still work and drive. Please wait for the tolerance to build; your patience will pay off. You can also look for a higher percentage of CBD with the THC, the CBD moderates the effect of THC, but maintains good potency for healing. ~Dennis

        • Sirs/Madams

          Too many patients whom are relatively inexperienced with the use of cannabis usage fail to realize the power of the essential oils from these heavenly plants. The essential oils extracted from the female cannabis indica/sativa plants are extremely powerful and have a profound “positive overall affect” on the Human biosphere. When vaporized or eaten, the oil effectively permeates our physical body and performs it’s job of seating important (too often “missing”) endo-cannabinoid receptors which are vital to health and healing and for annihilating cancerous cells in the body!

          With this medicinal POTENCY of cannabis oil comes very serious PATIENT/CAREGIVER RESPONSIBILITY! At some point there must be more education on how to properly dose any so-called cannabis oil, Rick Simpson Oil or by any other name. I’m getting far too many people reaching out to me in desperation…and sometimes they are just freaked out that the medicine for which they placed so much faith was turning them into a DEAD HEAD! LOL! Well then SLOW DOWN PARDNER! You’re riding too high and too fast TOO SOON! Your bound to fall unless you can get used to the altitude and the speed very quick… not so with most people…me included! We all have to start somewhere in our personal healing process :-)

          Unfortunately, many people go on to DIE unnecessarily because someone somewhere along the line in their care failed to take responsibility for administering their medicine properly and also ensuring there is an accompanying change attitude about food and drink…LOL! I find it heartbreaking that so many good people experience FEAR based on their personal experience attempting to “dose” on cannabis oil strictly medicinally. But it’s far too much FRACTAL ENERGY on a newbie’s psyche and they sometimes FREAK OUT! OUCH! DON’T LET THAT HAPPEN…(are you listening caregivers?) Too many needy patients will remain IN FEAR…and some may suffer and die needlessly due to failure to perform due diligence with the this sacred oil. Shame…shame…shame to caregivers and growers of this incredible edible medicine for not informing people of how to respect and use cannabis oil!

          I say —> RESPECT THE MEDICINE <—…take as slow as and individual "patient" can assimilate at first to build up tolerance…taking too much oil too fast may cause a temporary mental melt down…for sure….even with me when I mess around with it…. LOL …but it's safe and the feeling passes.

          A patient should start according to his/her own ability then BUILD UP AS FAST AS YOU CAN (double tolerated dosage every 4-days up to ONE GRAM PER DAY to treat most serious cancers) to one gram per day, then after approx 90 days you will see miraculous results. The exception, those who die, appears to be those whom have either destroyed their body with dangerous chemo and radiation and/or perhaps their bodily situation was too far gone to stop the insane destructive power of unchecked cancer cells. :-(….. "CANNABIS KILLS CANCERS"…and it has been proven time and time AGAIN! Use the oils with RESPECT and the oil will RESPECT YOU back…I think ;-) The answers to dosing is in Rick Simpson's book, The Phoenix Tears… (goto: and look for the kink to the "e-Book there…it's 10 bucks for lots of useful information about cannabis oils) PEACE!

  43. Jim,
    I can relate to your situation. I also spent a good chunk of change and got what I THINK was a good batch of oil– although it had NOT been tested. I was a complete ‘virgin’ with respect to intake of ANY type of illegal drug and I think it takes longer for someone like ‘that’. I had to abandon my first attempt with the RSO because I was unable to function well at work. I’m a retired teacher with prostate cancer. I was diagnosed with stage 3 prostate cancer, Gleason 6 biopsy results. I had lab slides examimined by 2 different urologists (including Mayo Clinic) It was recommended that I have surgery– but I declined. I’m currently on my first full week of full dosage RSO for attempt #2 at killing my cancer”.
    I have a question for someone. Are there any symptoms that indicate prostate cancer has (or is currently) spreading to the bones.

  44. Hi there,
    Am trying to find a supply of hemp oil for my father suffering from pancreatic cancer. Would you happen to have any leads for supply in Canada?

    • Health Canada has a medical marijuana program and will sell you the buds to make your own oil. You just have to have a doctor fill out some paperwork for you. The only thing is that the buds they sell are only 10 -14% THC, which I am told should be higher for cancer treatment. However, it may be better than nothing. From there you can make the oil yourselves. I believe the price is around $5/gm.

  45. Hi Dennis,

    I have just been diagnosed with prostate cancer. Gleason score 3+4=7. I am 47 years old and had no symptoms. My first annual PSA test came back at 6.7. My family doctor put me on antibiotics for 10 days and rechecked my PSA. It came back at 5.3. Tried another 10 days of antibiotics and PSA came back at 5.0. After my biopsy the urologist suggested a bone scan and CT scan. I have heard CT scans give off radiation which may not be good for cancer but I have not heard anything bad about the bone scan yet. I want to take things slow to get all my information but I am also scared that I might wait too long. Could I ask you a few questions?

    Are you currently cancer free?
    Would you recommend bone scan and or CT scan?
    Have you heard of a drug called Avidat? If so, What are your thoughts?
    Have you heard of a supplement called Albaplex? If so, What are your thoughts?

    I am being pulled in so many directions from surgery, radiation, drugs, supplements and now hemp oil which sounds like a miracle cure. Can it really be so simple?

    I am a husband and father of 3 great kids that I sooo want to be apart of their lives. Although I don’t know you, I feel you are a wealth of knowledge and I am in desperate need of your guidance.

    Thanks, John

  46. John,
    I’m not Dennis, but I have been TRYING to duplicate his results with regards to prostate cancer. I know what you are saying with respect to being “pulled in opposite directions” among the many possible approaches out there.
    I am NOT as knowledgeable as Dennis, but I’ll give you my thoughts, which should not be construed that I’m giving medical advice.
    I have tried a number of alternative approaches (Hoxey, ph diet, vegan, vegetarian, intravenous Vit. C). I’m currently taking RSO in an attempt to kill the cancer that I do have. My PSA started out at 5.7 — 8 years ago. It is now at 23.9. I will be taking another PSA in about a month, at which time I HOPE to have some good results.

    As for the supplements you mentioned– I’m not familiar with either. I’m VERY skeptical of ANY drug/supplement that is patented. If you can find a medical doctor who you trust– that’s a plus.

    Good Luck!

  47. Hi John – My urologist considers that I am in remission, as my PSA has remained below 4.0 for three years. I don’t know about Avidat or Albaplex. Yes, scans cause radiation damage. Anecdotal reports suggest that cannabis extract can do it all, but everyone is individual. You have to live with the decision, and have to choose whatever you have the most confidence in. For me, as a chemist, I felt confidence in the existing research literature, so it was fine to reject chemo, radiation, and surgery. And it worked out just fine for me. But you are different; you must believe in whatever path you choose. ~Dennis

    • Hi Dennis,

      Thank you for getting back to me so quickly. Are you saying that a bone scan can also cause damage too? In regards to your cancer in remission, does your urologist do other testing besides PSA like ultasound, biopsy, or MRI to determing the extent of the cancer or lack of? If so, were these test performed recently and if I’m not getting too personal what did it show? I am just wondering if the hemp oil might just be masking the PSA levels somehow.

      Thanks again, John

      • Hi John – I’ve not recently had any scans or biopsy. I’m certain that cannabis does not mask PSA. The only thing I know of that does, is the class of androgen inhibitors, like Lupron. ~Dennis

  48. Hi Dennis,
    This is Rick with the question about THC and CBD.
    Thank you for your quick reply to that question. Well, I have 5oz. of bud to start my recovery.
    I have just ordered the equipment to make a batch of oil.
    I have my trepidation’s about working with solvents. I have read where it is absolutely essential to use naphtha as the solvent for cancer.
    This question is way beyond the call of duty Dennis; do you know anyone in the San Diego area that could help me make the oil? If not I understand, however if you know someone I can trust out here doctor, friend, or trustworthy acquaintance any help is much appreciated.

    Thank you for all that you are and all that you do.


  49. Rick – Naptha is certainly the most efficient solvent for cannabinoid oil; but it is much safer to use pure (or close) ethyl alcohol, it works. I don’t know anyone down south; I recently moved here from Texas, so haven’t made many acquaintances. In the Rick Simpson video, you can just substitute ethanol. ~Dennis

  50. Thanks Dennis. I’ll give ethyl or ethanol a go.
    Courage is not measured by what is easy to do.
    Forgive me if this is too personal. Are you in California? If so welcome.
    The abundance of information on the different websites can cause me confusion. I have done so much research and in so doing have found unintentional conflicts and distortions regarding directions. As well, sometimes dogmatic statements are made regarding solvents and procedures. Thank you for clarifying.
    I think I have the same condition you cured on your behalf. As you know, you are giving me valuable information by means of which answers the questions I have, and instills confidence in my ability to get the oil processing correct.
    The ambivalence of making a useless medication by using the wrong ingredient or using a carcinogen and perhaps making matters worse can be discouraging.
    Your guidance and answers are greatly appreciated Dennis.

    • Rick – The universe is a conspiracy for our benefit; we have to remember to ask for what we want. You’ve asked the right questions. Happy to be in California, life is good here. ~Dennis

  51. Hi Dennis,
    The main reason for my post is to say thank you for being courageous enough to share your story with the rest of the world. You are an inspiration! Your position in the medical community adds tremendous weight to your story IMHO. Thank you, thank you!
    Thank you also to those who have posted their experience here for others to benefit from. Please continue to spread the word. We need to end the ridiculous propaganda campaign our government has perpetrated against this most wonderful healing plant, all in the name of profit for a few at the top, and at the sometimes ultimate cost of the rest of us. A bigger crime has seldom been committed by any government against it’s own people. Think of all the lives lost unnecessarily to illness, and all those lost or ruined by incarceration for the use of a plant! It needs to stop now, and the only way to achieve that is through proper education of the public. Tell your story! Don’t be a hypocrite! Don’t hide in fear! Of course we need to use common sense so that we don’t end up in prison as well, but we can focus on those around us that we know. And encourage them to share the story with others. We are well on our way, but we still have far to go and we must keep the momentum moving forward. Every positive outcome adds to the irrefutable evidence that already exists. Soon the scales will tip irrevocably in our direction.
    I live in a legal medical state, and am a legal patient due to neuropathy. I had a failed discectomy in 2005, then in late 2008 an epidural used during surgery for diverticulitis was inserted improperly, leaving me with severe neuropathic pain in my left leg and lower back. During my ten days in the hospital my left leg was virtually dead, but it sure woke up after I was discharged!
    What followed was a steadily increasing number of narcotics and other pharmaceuticals, including a fentanyl patch, OxyContin, hydrocodone, flexeril, cymbalta, Lyrica, and a few others. It was an endless cycle of increasing dosages, and increasing pain and side effects. I was not only not getting better, I was adding so many side effects from the meds I was having to take more meds to combat them, and see more specialists to treat the added symptoms. Meanwhile the neuropathy spread with a vengeance to my right leg and up my back and neck, and into my head and down my arms. I was convinced that I was dying.
    In January 2011 a good friend suggested I try cannabis, and gave me some, along with some great medicated brownies. Within eighteen months I was done with all the pharmaceuticals. My primary care provider gave me a prescription for methodone, which may have helped me get over the narcotics, but it also made me very sick and unable to eat. Cannabis overcame the nausea and allowed me to eliminate the methodone in one quarter of the prescribed time. All without hospitalization or visiting a clinic. Along the way I also managed to go from four hypertension meds to one at a quarter of my previous dosage. And from two cholestol meds to none. The final stages of those last two were helped immensely when I became a vegan in March 2012.
    The importance of the right doctor is key also. My doctor is a DO, and is much more open minded about alternative medicine than most MD’s. He has been an invaluable guide throughout the whole process, and will continue to be. I would encourage anyone to try to work with your doctor, or find one that will work with you. My doctor told me he had never had a patient manage his own health care so well, and has used my example to treat other patients with cannabis. IMO, this is one way that we as patients can help turn this whole crazy mess around. I, like most if not all of you, saw what “modern medicine” was NOT doing for me and decided to do some research on my own, and share it with my doctor. We need to educate them sometimes. For three years now I have been sending the updated versions of Granny’s List along to my doctor, and he uses it. Support your position with facts!
    After buying from a couple caregivers initially I decided to grow my own, and have been treating my neuropathy mostly using a vaporizer. I do consume some edibles, but have struggled with consistency in dosing. Finding the right method of decarboxylation is the first challenge, especially when we are so limited on number of plants and amount of medicine allowed in possession. Experimenting is very expensive. Good medicine is a terrible thing to waste!
    I have learned many things since my journey began, and have much more to learn.
    I’ve learned that properly cured medicine is far superior. Ninety days in a glass jar is a minimum IMO, and a year is even better.
    Edibles are more effective than inhaling if the dosage is right, in my case at least.
    Different strains do seem to have different levels of effectiveness as well. I suspect THC/CDB content largely determines that. I have not been able to try a high CBD strain yet, but intend to ASAP.
    I have been unable to work since early 2009, but am now beginning to feel like there is light at the end of the tunnel. And at age 55 I still feel like I have plenty to contribute. I believe marijuana holds the key that I seek. I still suffer from neuropathy, but it is less severe than at any point when I was using pharmaceuticals to treat it. I’m even learning the triggers that make it worse, and how to combat them.
    I realize this post is primarily about cancer, not chronic pain. However, I believe many of the same associated issues are shared by the two. What I have found on this site will be beneficial to me. I hope my story can be beneficial or even inspirational to someone else.
    Peace and love to you all!

    • Terry – thank you for articulating these salient point. Now we must thank our precious and charming blog hostess, Nunya. She has given everything and asks nothing in return in offering this forum for the verifiable truth about this cannabis medicine. I’m sorry you had to suffer medical treatment, but now you can heal and get your life back. ~Dennis

      • Hello Dennis…

        Keep up all the great work !!

        Does anyone have any information
        or advice on how to successfully:
        Combine Hormone Therapy (lupron
        3 injections…June …September
        ….and December 2013…with the
        Rick Simpson protocol….

        We have procured good quality oil and it is
        properly made oil and had it
        properly tested ….at a certified lab..

        THC = 37.6%
        CBD = 0.51%

        No toxins… No mould….using everclear (food grade) solvent

        We started the lupron shot yesterday…followed by Casodex….
        will be on Casodex for 25 days @
        50 mg daily dose…

        We are hoping to see the Lupron
        do it’s job….we are confident the
        PSA will decrease…..current psa
        June 1/13 was 2.10….psa May1/13
        was 1.1 and April1/13 was .59

        RP – Sep/2011
        Clear margins….micro metastatic
        spread to lymph nodes..
        Final Gleason 9/10
        Completed HTherapy…. Lupron
        last year …Oct2011. Jan/2012
        and last injection Apr/23/2012….

        Current X-rays….. Doesn’t appear to
        have spread to bones…..removed
        3 lymph nodes that tested positive
        for metastases…..

        We should be up to the required
        RSO dose by the end of June….

        Can you offer any advice or
        suggestions….. We’re determined
        to share and document our story….
        so that others…. can learn and
        benefit from our experience….and
        we can continue to move forward
        in our journey..



        • Charles – I do have an opinion about mixing Lupron in with cannabinoid therapy. This is the best model I know of to treat prostate cancer. Lupron and Casodex slows the growth of the cancer and THC kills it through known pathways. Your time-release injection will give a steady inhibition to androgen and the THC will take care of the rest of it. There is one more thing I would suggest. Eventually you will want to get a higher percentage of CBD (1:1) if possible. We know that CBD inhibits the gene (il-1) that allows the cancer to spread. So the plan is to kill it, then keep it from spreading. Best of luck to you. ~Dennis

  52. I have not been following this blog as well as I would like, but have read everything at least once anand I’ve made a couple of my own entries relating to prostate cancer and RSO. I am currently on my 2nd attempt to duplicate the resultf of Dennis and possible others. My first failed attempt lasted a couple months before I was forced to abandon my efforts because my digestive system got all screwed up and I lost 20lbs. You might think that’s no big deal, but I was a trim 6ft 175lbs. NOTHING was appetizing. I had to FORCE myself to eat. I also had headaches and short-term memory problems at times.
    I thought I probably pushed the envelope increasing dosage– because I was a THC ‘virgin’ (I’ve never used marijuanna in ANY form).
    I was disappointed but not discouraged. I let my body rest for about a month– and I started again– going much slower on increasing dosage. As before, my prostate symptoms seemed to improve and ‘things’ seemed to be going well until about a week ago. As before, I started to lose my appetite and my weight (went down rapidly again (I’m now at 160 after losing 10 lbs in less than a week. I stopped RSO for 24 hours, which seemed to help a little. I started back with a VERY small amount and I made it through the day, but last night the ‘shit’ hit the fan again– and I thought I was going to die. I did NOT take my evenin dose and made it through the night OK. I have not taken RSO for about 36 hours and I am STILL not doing well.
    I can relate to the many who seem to have the same– or similar problems of one sort or another. If there is ANYONE– in addition to hopefully Dennis– who has ANY suggestions— let me know.
    I only have about 40ml of RSO remaining. My RSO was not tested, and I might consider another attempt— IF– I can get a batch that includes plenty of CBD (as suggested by DEnnis).
    So far– I’ve made it a little over 8 years from my diagnosis. I have avoided surgery, radiatin and/or chemo. I’m NOT a quitter, but I am acknowledging the fact that I could SURE USE SOME HELP!! My last PSA was 23.1


    • Well with so many variables it is tough to say. It is of utmost importance that all solvent was eliminated during your evaporation process.The littlest bit of solvent could give you similar side effects. If made properly one should have tolerable side effects. If it was myself I would be supplementing my regime with some additional alternatives. B17, mms, sutherlandia, oleander are what we are in the process of starting to use for my dad at the moment who is a hesitant to try the RSO.

        • I obtained mine online. If you are unfamiliar with these products, it would be best to spend a bit of time online and see if you are comfortable with the products.

    • Hi Rod – Sorry to hear you are not doing well on the regimen. If you want to continue the cannabis healing, I would suggest very light doses in the evening to sleep through the mental effects; until you are acclimated to the dose. Once you have tolerance to that dose, kick it up a little, etc. I’m glad you know that CBD inhibits THC mental effects, but does not interfere with the essential action of THC killing cancer through taking down the mitochondria to starve the cell. If you can find a blend of roughly 1:1 THC:CBD, you will have a better healing experience than high THC. CBD is strongly anti-inflammatory and has been shown to work against cancer as well. I’ve heard that strains of Blue Jay and Omrita are both approximately 1:1, in case you can find them. Best of luck, ~Dennis

      • I still have about 40ml of the high THC batch of RSO. I’m thinking I might try to use that up to help my body adapt– then I’ll try to secure a batch of the 1:1 RSO you suggested.

  53. The high THC will not be wasted in small doses. Even small amounts are effective at killing cancer cells. I started with cannabis butter, only a small fraction of the potency of RSO. Just the butter alone killed the primary prostate tumor. But still, once you get going, it’s good to take as much as tolerable. ~Dennis

  54. I have a few questions.. Is anyone on here that can help me? these questions are a matter of life or death for someone close to me.. Please help me

  55. Hi Dennis,

    In regards to 1:1 THC/CBD. I am confused on the percentage. What is considered the high potency required to kill prostate cancer cells? 50% THC/50% CBD, 60% THC/40% CBD, 40% THC/40% CBD? What do you think the most ideal percentage would be and is that obtainable?

    Thanks, John

  56. Hi John – Honestly, I’m not impressed at really high potencies. I did fine on 22% THC and CBD. Having extreme concentrations just means you take less of it. That’s okay I guess. But I can’t really say from my experience that it is necessary. Cannabis kills cancer, whether it is 10% or 75%; ultimately you have to adjust to the concentration you find optimal. If I had to do it all over again, I would not choose anything over 30%. No doubt there are other opinions about this, and that’s fine. ~Dennis

  57. Hi Dennis…Thank you for your first hand experience. So going off what you said, 22% THC with 22% CBD or 30% THC with 30% CBD is what you might recommend? If you had a choice of THC or CBD being a little higher than the other what would you choose? Would the Blue Jay or Omrita that you talked about fit into that category?

    • John – We probably won’t see exactly 1:1, there will always be one more than the other. Both Omrita and Blue Jay have a little more CBD than THC, and this is perfect for me dealing with prostate cancer. PSA is an indicator of inflammation more than anything else. CBD is strongly anti-inflammatory and could (theoretically) help knock down PSA. I’ve not seen any science on this, but I should have more information in a few months. This is a game of tolerance; and everyone’s tolerance to cannabinoids is different. Tolerance increases over time, so using cannabinoids therapeutically is highly individual. So we experiment on ourselves until there are some industry standards; likely not anytime soon. But this we know: cannabinoid extract kills cancer cells without harming normal healthy cells. This is a first. ~Dennis

  58. Hi Dennis,

    What are your thoughts on using hemp oil with approximately 50% THC / 2% CBD and using a CBD supplement to acheive the 1:1?

    Thanks, John

    • Hi Dennis,
      I do not know too much about the CBD supplements. The person I talked with is requiring a doctors diagnosis from me first before he will give me more details. I think it is legit but can’t say for sure yet. I wanted your opinion to see if this is a viable option before I spent too much time on it. I would love to talk with you more about this. I left you my phone # on your Facebook.

      Thanks, John.

  59. Hi Dennis,
    I watched your videos online, I am very happy to learn about the treatment. I am from Australia, I have one of my family members in the US and she has one of her family members dealing with brain cancer, she is very busy getting a lot of things organised and so is unable to do anything else and so I am trying to do as much as i can in terms of gathering information. Is there anyway she could get in touch with you, she is genuinely confused and needs a few answers that would help her a great deal. any sort of help would be greatly and deeeeply appreciated. Thank you

    • Aseem – I learned everything I known from the Rick Simpson video “Run From The Cure,” and from Dr. Robert Melamede’s videos. Ask your family member to watch these YouTube videos. She can post here as well. Wishing you and your family the best. ~Dennis

  60. Really interesting story, congratulations on finding a therapy that works for you. Out of curiosity, you went to school at the University of Houston and Baylor, what were your degrees in? What research did you do there?

    • Hi Al – From U of H my degree was Chemistry with emphasis in Biochemistry. At Baylor Medical School I attended a year in a course on Medical Physiology and BioPhysics, funded by a National Health Institute grant, that was supported by M.D. Anderson Hospital and Tumor Institute where I was employed in the Experimental Anesthesiology Department doing research in advances in anesthesia for patients undergoing radical surgery. ~Dennis

  61. Advice appreciated:
    I was diagnosed with prostate cancer 8 years ago with a biopsy (stage 3,with Gleason of 6). I have resisted ANY type of ‘normal’ treatment and have tried a number of things, but my PSA has continued to go up (now 23- after starting at 5.7). I have tried RSO twice but get VERY sick after about a week after I get to full dosage.
    I recently found out that I PROBABLY should have been delivering the oil in a suppository instead of –or– in addition to oral delivery. Can, you, Dennis– or anyone else tell me how I can use this method to perhaps avoid the extreme nausea.


    • Hi Rod – I have not used the suppositories, but several people I know have commented that they had very good results with suppositories. You can get sheets of suppository molds to fill and freeze; sorry I don’t know a source. Could your sickness be caused by remnants of solvent left in the oil? Best Wishes, ~Dennis

  62. oh my God’ I want to thank Dr obi Akpo for curing my daughter cancer which she has suffered for the pass two years by helping me get the cannabis oil, and instruction on how to use it. immediately I read some testimonies to his credit I decided to give him a chance and after some weeks precisely after applying the hemp oil I saw great improvement in my daughter health. as I am writing this testimony I can say my daughter is completely healed. any one out there who need help, please feel free to contact this Dr with this email address:
    Mrs Karina

  63. Hi, has anyone heard of RSO and celiac disease and multiple chemical sensitivity. I have a family member suffering from both and those are devastating diseases. Your input is appreciated. Thanks.

  64. Hi Dennis
    Do you know anyone that has used Rick Simpson’s Oil and experienced rising of their body temperature
    from the normal +- 37°C (96.8-99.5°F) to 38°C (100°F) or 39°C (102°F) ?
    a friend of mine is taking the oil 1 rice size three times a day.
    if the oil is not taken for one day, or two then the temperature goes back to normal.
    Don’t know what’s causing this.
    Any information is appreciated. Thank you!!

    • thanks for the reply.
      She says that after she takes the oil during the day, all of the thc and cbd effects kick in, but she stays active and tries to keep up with her activities, and then she feels a light cramp in the leg muscles, after that, comes the temperature rising.
      Maybe she don’t have to be active that much. Or none at all.
      don’t know.I’ll keep looking for other testimonials. Maybe I’ll find something. Thanks again.

  65. I have advanced prostate cancer; bone mets, lesions. Right now i am not on a pain patch. I have hot flashes, hot and cold spells, etc., and am trying to gain back some weight . Does anybody know of other stage 4 PC cases out there? Any luck?

    • Had a friend with stage 4 that had met to his bones and used mms(chlorine dioxide), he has been declared cancer free.

  66. Hi Dennis my dad was diagnosed with stage 4B prostate cancer it has spread to his bones and all the way to his brain his PSA is somewhere near 4,000 they gave him a year to live. They say he has probably had it for about ten years without knowing. I have done a lot of research about your studies and im having him take a small dose of oil everyday. He has never been a weed user so he gets very stoned unless i give him a extremly small dose i am hoping he will build a tolarence shortly and start taking larger amouts. my question to you is have you ever heard any success stories of people with prostate cancer that had gone through the bones to the brain?

    • Hi Katelyn – Sorry to hear about your dad. I do not know personally any one who has overcome this extreme circumstance. However, I have seen several reports of remarkable progress in a short period of time. Even though this is a last resort for you, I think your dad can make real progress, and provide an improved quality of life for him. Taking a large dose at night will let him sleep through the drowsy part; and a smaller dose during the day so he can be awake. I’m optimistic about his making progress. And he will build tolerance quickly so he can take more of the medicine. ~Dennis

      • Thank you we will keep fighting, your work is so inspiring and is giving us a little hope, that means the world to us.

  67. Hi Dennis,
    Everything is well.
    Since you are in the State; do you know theCalifornia law. Is it legal to separate the oils form the plant with alcohol?
    Sorry if this is off topic. I am looking around online and can’t seem to locate anything specific?
    Thank you.

    • As far as I know, California law does not prohibit Cannabis oil extraction using alcohol or any other solvent. I’ve heard of co-ops that use this method and they are legal. ~Dennis

      • Hi Dennis,

        It would be easy to get there. One of my oncologists is in the area. Beats going to Nova Scotica. My location is in San Diego, Ca. What did you have in mind? Nice Birthday question (Aug.19,) thanks for writing to me on my birthday.

        Kind regards, Rick

        • Sorry for the confusion Rick, this is Pete, not Dennis. I’m trying to work out how to PM you so i can send you a message.

      • Dennis,

        I am going to ask the right question I hope.

        Really, Dennis I can be up in Santa Cruz in a few hours. Will you please help me?

        Thank you, Rick

      • Hello Pete,

        1st Thank you for the reply. I’m sorry, how are you and Dennis related? Please do not misunderstand me: I appreciate your help. Are you part of the same co-op? Going for 4th lupron shot in Sept. that is nasty medicine but, it’s keeping me alive until I can hopefully cure this with oil. The chemo-people are pushing now! Don’t want to ruin everything with chemo. Chemo a 3% cure….right. Do you FaceTime on Ipad? Do you have a number for PM e-mail or phone number? I woud really like to chat with you. Thank you Pete, Rick

        • HI Richard,
          Just to clarify I’m not related to Dennis at all. I’ve just been following his comments, and progress on this site. Sorry to hear about your situation, I should say at this point, I’m no expert but can share what I’ve learned on the last 9 months of this journey. b l a b b e r F i sh (at) Y a hoo (dot) co (dot) (uk). (we can exchange skpe or phne – i dont hve facetime. I must, specifically with prostate Dennis has direct experience in this area and tends to answer most requests on this site (just to reiterate, I dont know anyone on this site and cant vouch for anybody. One last thing, beware of many of the fake adverts around.

  68. I have been diagnosed with prostate cancer and really wonder where I can find the oil. Is there any website or consultant who can quantify the validity of all the sites that claim they have RS oil? Thank you

    • Mark, it depends where your located, if you lucky enough to be in California or Colorado you should be able to find a good source, I’m just trying to work out how to use the PM option , when i do ill send through some options (i cant personally verify the options because I havent used them, im judging by the website and advice of other posters)

    • Mark – I thought there was an ption to send private messages but I cant seem to find it. My email address is in a comment above, you can contact me on that.

  69. Dennis – congratulations on keeping on winning brotherman, all power to you and all others on here fighting to save their loved ones. Just a clarification please Dennis. Oil made using the method shown on Ricks film will be THC not THCA (i.e. its been decarboxylated) because it is heated during the process of making of the oil when boiling off the alcohol.

    Is this correct?

    One Love


    • Glenn – You are correct, heating the oil to a specific temp for a specific time will decarboxylate THCA to THC, making it an effective anti-cancer agent (among other things). Only THC will fit the CB-1 receptor, not THCA. This is extremely important if you use cannabis for cancer. ~Dennis

      • Hello Dennis,

        My name is Pete and i have been using high thc oil to cure my cancer( chordoma) for the past 9 months or so. I ingested around 60g. Don’t know how high in thc the oil was but had very little cbd( maybe 1%). In fact was BHO. Just had the MRI and the tumour size has not changed since 14 months ago. No growth no shrinkage. To be honest i was expecting little better results but i am still happy with no growth.
        I been following your posts for a long time( i am a big fan of yours) and i have noticed that you like the 1:1 thc/cbd ratio.
        Is it for the simple fact that thc could work on some cancers and cbd on others?
        What do you suggest?
        I would like also to mention that i could only take on average 0.25g a day of the BHO. No chance getting to 1g/day. Far to potent. Would this be the cause that my tumour did not shrink?
        Thank you Dennis and God bless!

        • Pete – My rationale for 1:1 THC:CBD is that recent science has shown that CBD has numerous anti-tumor attributes. Also it modulates the mental effects of THC so that you can take a much higher potency. Take your large dose at night, and sleep through the mental effects. Small dose during the day to function. As you adapt to the dose, increase constantly. To kill cancer you have to hit it hard. Perhaps you are being too gentle with the cancer. Hope it will respond with increased dosage. A quarter gram is a little light. ~Dennis

        • Hi Anon, I had a friend that had a Chordoma (Brain Tumour). They told her it was non cancerous. She had surgery to remove as much as they could, as it is a brain stem tumour and went all the way to California (she was Canadian) for proton radiation. This gave her 12 yrs to live her life normally. As normally as you can with no palate (roof of mouth). Eating was always an issue, because she gagged alot. 12 yrs…and it began growing again. The Dr’s said they could do nothing more for her other than offer meds for pain…anything. She didn’t like the way the Oxycontins made her feel, and didn’t kill all the pain. She was given a Cannabis Brownie…she felt BETTER!
          I told her about watching Run From the Cure, and she began ingesting Cannabis Oil, made as per Rick’s video….to the letter….with 99% ISO. Her pain disappeared and she lived a relatively normal life, resuming her activities and very functional. 2 yrs, and the Dr’s convinced her to go onto Dexamethazone for the swelling. Steriods = DEATH SENTENCE!
          She took 1cc daily of the Cannabis Oil for 2 yrs and it never did reduce the tumour, just gave her pain relief and appetite. She died this past July 2013. White Widow was used as her Cannabis, organic. I wish we could have saved her.

      • Thanks Dennis. Just to be clear then, is it right that the oil made in Ricks film would need to be heated to 240 degrees for around 30 minutes in the oven AFTER its been made in the fryer, to be decarboxylated?

        This is really important because Ricks film doesn’t say this in the instructions. As water boils at 100 degrees, the boiling off the alcohol process does not decarboxylate the oil because this requires 240 degrees


        • Decarboxylation is simply removing a carboxyl group (CO2+H) from the phytocannabinoid THCA to create the active THC, that will now fit the CB-1 receptor on certain cells. This process occurs simply through heating. You can use high heat for a short time, or medium heat for a longer time. High heat destroys much of the beneficial chemistry of the cannabinoids, terpinoids, and flavinoids. The optimum temperature is 240ºF. for 30-45 minutes. There is much opinion about the process, but this is a good place to start. So as long as the plant material is at 240ºF for 45 minutes, it doesn’t matter where in the process this occurs. ~Dennis


  71. Hello Dennis, My wife’s Uncle has early stage Alzheimers and has been diagnosed with Prostate Cancer and possible mestastasis to the lymph nodes and bones. I have been following and studying RSO and the benefits for many many months and have approached the family about using RSO primarily to halt the progression of the Alzheimers but now more crucially the latest diagnosis. Im up against it as they seem to take notice far too much about the establishment and the ‘treatments’ they have to offer. Selfishly, i see a lot of trouble ahead for all the family as ‘Uncles’ state worsens, this affects all members of the family in every way. I personally want everyone to be able to cope, ‘Uncle’ lives with his mother because of his Alzheimers and the break up of his marriage, his mum is 83 so will and is suffering to cope. The reason I am revealling all this is so you may write a comment to me/ us advocating the RSO. I have purchased 1:1 CBD/THC seeds months ago ready to begin a grow and production but will not until they give me the go ahead. They, meaning my wife’s mother and father as they are power of attorney for Uncle. Please help me help them, your story holds so much weight.

    Thanks Grahame

  72. Grahame, would appreciate it if you could let me know what exactly 1:1 CBD/THC levels are. Some people have mentioned 50% THC and 50% CBD. I have not seen any oil or plant with more than 2% or 3 % CBD.
    Would appreciate any thoughts.

    • Grahame – 1:1 means the same percentage of THC and CBD; whether that is 10% or 38%; all the same. Higher CBD is rare to find, but is getting more available. ~Dennis

  73. Pete/ Dennis, the seeds i have are CBD Crew Skunk Haze; distributed by Dutch Passion out of Holland. The actual percentage is 5% CBD and 5% THC; they are the only company (CBD crew) to my knowledge who have cross bred to give a perfect ratio for medicinal use. Yields are 450 grams of bud per m2, and as Dennis says the ratio is all important not the total percentage so you just take a larger dose dependent on tolerance.

    I will look at your link Dennis and show my inlaws. Lets hope they take notice. thanks for your input. Grahame

  74. HI Dennis,

    A big thank you is in order. The inlaws have read your web page and subsequently have asked me to begin a grow of Med Canna as detailed earlier. By the way we are from the UK so we have to be careful to say the least but well worth it if we can help uncle and the rest of the family. Thanks again and ill keep you all updated. Grahame

    • Grahame – we look forward to your updates on this amazing adventure into the healing domain of cannabinoids. Warmest wishes for your success. ~Dennis

  75. To Mr. Dennis Hill..I need your help please
    In August,,30,2013 i got the result of my prostate biopsy and found aggressive prostate cancer..I search in the internet and find the best treatment is cannabis oil..But I don’t know how to get the treatment ..and don’t know u email,,address or u number to contact you..please call me on (713)560-7746 or email me on live in Houston,TX
    Best regard and God bless you

  76. To Mr. Hill and All,
    I’m reading the Rick Simpsons’ “how to” and I’m bit confused:

    has anyone else noticed (or I’m wrong).. that for you to make a good hemp oil, Rick Simpson recommends a strain that is high with THC
    (“When buying or growing hemp, procure a strain that has the highest possible THC content”) ,

    and later in the text :

    (“. At this time all I can do is tell the public to order strong Indica or Indica dominant Sativa crosses that have 20% THC or more, to produce their oil.”)

    (“For most other medical conditions, I strongly suggest that Indica strains be used. Indicas relax a person and provide them with more rest and sleep.”)

    From my understanding it is not that Indica has more THC , but it’s the other way, it is Sativa that is with more thc than indica.

    so what do you think should be used for a good oil?
    Sativa or Indica ?
    (my friend is using hybrid.. I believe it’s Skank , to produce the oil)

    With what do you make your oil ?
    I also want to share the info about a possible side effect ?
    (which slowly dispersal once you get used to the dosage)
    when using a dose that is higher than a body can tolerate at that moment, the body temperature rises during the day for few hours and then goes back to normal.

    • Hi Bob,
      Thought i would add that i understand your confusion. There seems to be a variety of opinions online with regards to THC & CBD levels (some say high CBD is important, others say high THC, some say both high at equal levels). I must say I’m as confused as you and it seems to be very hit & miss. There is no standardized method, this is resulting in the oil apparently working for some and not others (in terms of eliminating cancer).

      • The facts are that THC directly kills cancer cells without harming normal cells; and CBD shuts down the iL-1 gene that kills the cancer’s ability to metastasize. So it seems to me both together gives us healing and keeps it from coming back. ~Dennis

  77. Dennis,

    What if you get your Cannabis from an unknown source and it was treated with chemicals such as organophosphate. Then you made it using Rick Simpson’s method with 99.6% Isopropyl Alcohol, is there a risk of getting organophosphate poisoning this way? Someone mentioned in another thread that the ISO alcohol will strip the organophosphate molecules along with the THC and CBD and then these poisons can bind to the alcohol which can form an ester and can be deadly. Does this make scientific sense? I would assume if the organophophates indeed do bind with the alcohol then they will be evaporated with the rest of the solvent when boiling it off, correct? I made a batch of oil recently, I got my stuff from an unknown source and now I am afraid it would have been treated with these chemicals and can do some real harm. Please lend your knowledge and experience on this issue.

    One last thing, can the oil be toxic if some of the solvent somehow remained in the oil? If so, how toxic and what advice do you have to evaporate the remaining solvent if a coffee warmer or hot plate isnt available.

    • Organphosphates are neurotoxins that cause excess acetylcholine (a neurotransmitter) in the CNS. If there is any suspicion about a cannabis supply that has been treated with OP, best to not use it.
      The least toxic solvent is high % ethanol. The body knows what to do with alcohol; it just makes carbon-dioxide and water. So even if alcohol shows up in the oil, it’s fine. ~Dennis

    • If your interest is safety, do not use isopropyl alcohol, it is toxic to the body. It is a good solvent, but you do not want any of this stuff in your body. It is very different chemically than ethyl alcohol. To be most safe, use ethanol as your solvent. ~Dennis

  78. Dennis,
    RSOwholesale legally sells Hemp Oil which is advertised as “6 ten gram 18% decarboxylated tubes for about $3,600 with free shipping. They guarantee a high level of CBD and a minimum amount of CBD. They indicate that they do an organic extraction process which is very regulated and certified by their labs.

    Would this be good medicine for a man like me with Metastatic Prostate Cancer of the Ishium?

    Could it somehow be augmented with THC?

    Thanks for your response. Please email me you response to Also, let me know if you are available to counsel me and your rates.

    • SP Rich – Just my opinion, but I think that THC is the best cancer killer, however CBD also has significant anti-tumor effect. I think that using the two together is better than one or the other. Perhaps you can find a strain that has both. ~Dennis

      • Dennis, please let me know if you think 10% THC and 4% CBD will work for cancer. I’m also interested to know if the extraction process is important. The process described in this short video seems different from the ‘Simpson’ method :


        • The 10% THC and 4% CBD is fine for cancer. There’s no difference between five drops of 10%THC and one drop of 50% THC. It’s all good. On the video I cannot tell if the cannabis is decarboxylated or not. Cannabis must be decarboxylated to treat cancer. Make sure that the plant mass (or the extract) cooks for 30-45 minutes at 260º F. Some may think they follow Rick’s instructions, but if they do not know the importance of decarboxylation for cancer, it might get overlooked. If you use cannabis extract to kill cancer, use what ever method you like, but don’t neglect burning off the carboxyl group from THC and CBD.

  79. This is a question for Dennis. My husband has aggressive prostate cancer. He has been on the oil for 3 weeks plus supplements that should bring down his PSA. He was told that surgery is not an option for him! He had his first visit with the oncologist Sept. 25. The treatment recommended was hormone therapy and external beam radiation both have bad side effects. Our anxiety comes from feeling he has no time left to try the oil with out alienating the Drs. wanting to do the traditional treatments. Plus he has no way of knowing if the alternative method he is using is working without having more biopsy’s. We know your story and many others…any suggestions how to integrate the two methods of treatment and feeling confident that the oil will work?
    Thank you for your time.

    • Hi Gail – Here are couple of options for you:
      1. Do both medical and cannabis treatments. or
      2. Do cannabis with the hormone therapy. The Lupron (or whatever) inhibits androgen which drives the adenoma growth. This is good. It gives the cannabinoids greater healing power. Reevaluate with your oncologist periodically. Figure out what option you have most confidence in, and do that. You need to feel positive about your treatment choice. Being positive has healing power. ~Dennis

  80. Is there an extensive bibliography dedicated to peer-reviewed papers of the effect of RSO or other forms of in vivo cannabis on human cancer sufferers? Mr Hill mentioned Italian research as sparking his investigation. Such papers and bibliography would be helpful in presenting to our local cancer center director who insists there is no such research out there. A PubMed search wasn’t that helpful or perhaps my search technique was faulty. Thank you.

  81. It may’ve been overlooked by me on this site, but the anti-malignan antibody serum test, FDA approved, conducted by a Boston laboratory, validates with 99.5% accuracy, the level of cancer activity in the body. In my experience, and to my understanding, this AMAS test avoids having unnecessary MRI and mammography, biopsy, and other types of conventional screening. In the US, this test is FDA approved and paid for by Medicare. In Canada, the test must be requested by the doctor but in at least one province, the province then pays for the shipping, via courier, to the Boston lab but not for the test itself–which is US$165.00. Test results are available within a week of the blood being drawn. The test does not determine the location or type of cancer. But it does successfully identify occult cancers which the standard tests miss. Test results, as I understand them, range from 0 to 100 (normal), 120 to 130 (borderline) and over 130, the body is fighting a losing battle and it is time to call in the heavy artillery. The test is voided for at least 3 mos. if the client has had chemo/rad.

  82. Thank you Mr. Hill and Mr Doug for those very extensive bibliographies. A lot to sort through here. My friends with Parkinson’s would be interested in a similar list for their condition..

  83. Thank God Almighty that lead me to Rick Simpson who with his humanitarain heart help my son that had cancer of the brain with his Hemp Oil. I am so grateful that my 17 years old boy is back alive and healthy and can do all this thing he like without any hindrance in his life.
    Rick Simpson your medication is the only cure for cancer and tumor and from the bottom of my heart I say you are the best and i will always give thanks to God for you to have long life so you can help many more people on earth with your medical service to humanity. with you i now believe that the Hemp Oil is real and True, for all those who have problem relating to cancer and other diseases should contact
    Rick Simpson for his medical service at:,

    • Has anyone worked with the oil or other modalities in conjunction with the AMAS (anti malignan antibody serum test) test described above to track the fall of cancer cells in the body? OR, is a physician affiliated with a cannabis project able to prescribe based on the AMAS test?

    • The extensive bibliographies are most appreciated and have begun their circulation among the alternative medicine people here, one of whom is a medical doctor (relapsed). The conventional cancer center will be diplomatically introduced to the bibs at the first opportunity. But in my experience, unless people are asking questions, they are not ready to learn.

  84. having responded to a similar post as carolyn jouls about doctor morris, i suspect this source for rso is another scam. be leary.

  85. This is the real Rick Simpson and I am the man who brought this oil to the public’s attention. I am from Nova Scotia Canada and since the Canadian government gave me a criminal record for healing people, I cannot even enter the US and also I might add that I am not a doctor. The public should be aware that there is no shortage of con artists out there, who like to use my name to sell their products, so please be careful that you do not allow yourself to be ripped off.

    • Dear Mr. Simpson.
      Your frank warning draws attention to several dubious posts which should be removed from this otherwise credible blog. I am hopeful that in the next ten years, you will be vindicated. But after watching a 1:45 min documentary on Lyme disease and the courageous doctors who have been managing and curing it before losing their licenses due to pressure from insurance companies and self-serving “researchers” and patent holders (http: (//”) this vindication may be delayed.
      Can you tell us, please, what happened to your researcher, Larry Bjarnason? He died, this year, I think, but cause of death was not noted in the press that I could find.

  86. As the blog is so long and extensive, posting a warning at the top is likely to be overlooked. Maybe warnings posted at intervals?

  87. Hi, my sister had renal cancer and subsequent removal of the kidney. She now has a diagnosis of lung cancer metastases. She is being referred for high dose Interleukin treatment but is concerned that using cannabis oil may interefere with this treatment or may even jeopardise her chances of having the treatment if detected (she has been advised to tell the consultant about all the alternetive treatments she is using). This article states “Phytocannabinoids have the ability to suppress this inflammatory cytokine cascade by inhibiting glial cell production of the cytokines interferon or interleukin. ” Would this mean that it could have an adverse effect on the efficiency of interleukin treatment?

  88. I have a question for Dennis Hill. Did you do anything special with your diet such as raw foods, juicing, no meat or dairy etc? I don’t see in any of your interviews where this was discussed. Also, did you develop any symptoms while on the oil such as loss of appetite, diarrhea or weight loss? Did you monitor your pH? Thanks for any help you can send this way.

    • Hi Mavis – These are pretty good questions, thank you for asking them. My diet restraints are no dairy, no sugar (sucrose), no red meat. Sugar is acidic and highly inflammatory; cancer is also inflammatory, thus sugar provides the perfect acidic environment for cancer to thrive. While I was taking the oil I lost about 15 pounds due to low appetite; this is good, I really like being light. No diarrhea. Did not monitor pH, but prefer an alkaline diet. Now that I am on a maintenance dose of cannabinoid extract, I also take Soy Isoflavones to inhibit androgen, and selenium (as selenocysteine) to inhibit prostate cancer. I take the THC at night and CBD during the day to maintain good immune function. Hope this is useful somehow. Don’t hesitate to ask questions. ~Dennis

    • Mavis, ONE MORE THING. Here is something that I haven’t talked about before, and something you did not ask about…. Exercise. I start my day with meditation, yoga, calisthenics, weights; then go for a two mile run – every day. Exercise is so essential to healing. The cost is great for not getting exercise. Even in disability, we can do resistance training; like the astronauts in zero gravity. ~Dennis

      • Hi Dennis,

        Would you mind telling me how much cbd oil you taking during the day and if the cbd oil from Dixie Botanicals( 3.25%) is good enough for fighting cancer?
        At the moment I take only RSO, but nowhere near 1g because is too potent. I was thinking if I could mix it with few drops of cbd maybe would help me take more RSO.
        What do you think?
        Thank you and have a great day!

        • Pete – Since I can’t find high CBD cannabis locally, I use a CBD elixir spray several time a day. Recent literature is showing that CBD has anti-cancer attributes. Look it up; search CBD+cancer and see what you get. ~Dennis

  89. Hi Dennis, Thanks for all of your helpful info. Appreciate your availability here. Have you ever heard of someone having to discontinue the oil due to loss of appetite and weight loss? When you took the RSO for the final three months before maintenance, how much did you take in grams each day? Also, what solvent was used? We have been able to get about 80 grams in, in about 3.5 months. Body seems to be resistant to more, so had to cut back to only about 0.20 grams before bed.
    Thanks Mavis

    • Hi Mavis – Never heard of anyone quitting RSO because of no appetite. When I started losing weight, I just focused on eating food I really like. No biggie.

      > how much did you take in grams each day?

      Unknown. Grams is a weight measure and doesn’t tell what the potency is. Ten grams of weak oil might have the same benefit as one gram of potent oil. Rick says just get the best potency you can find. It is less important about the potency and more important about tolerance. Everyone’s tolerance is different. My tolerance is high so I take a lot. Others’ tolerance is lower, so they take less. Starting RSO we take as much as we can tolerate, then as tolerance increases, we increase the treatment dose. In this, the absolute values don’t matter; it only matters if you are taking the oil up to tolerance. ~Dennis

  90. Dear Dennis. I am a meditator and have studied alternative healing modalities ,diet for the last six years of my last stage prostate c diagnosis. We are growing our own cbd (swiss gold, cbd 17% to 8.7 THC. Rick Simpson , Constance Finley of oaksterdam U; and other researchers seem to think that the heavy THC content is the best way to go. We are also using an indica mix that has been tested @ 56.7 11. For use at bedtime. it is very stoney. My question Dennis is will this deliver enough THC to do the job. Or should we try to breed our own clones that will have the cbd and thc together. I think that what we are doing by using two separate strains is the inteligent thing to do. WE LOVE YOU AND WHAT YOU ARE DOING FOR EVERYONE. I am also writing a book that has over 200 pages done entitled ‘HEALTH BEYOND HEALTH CARE” which i have been working on for 15 years now.
    I would appreciate it if you could call, but i can only imagine how busy you must be. Will you be speaking anywhere soon? Anyway i also applaud you for supporting the position that a sick person should use diet, exercise, meditation , suppliments and most of all a intense bowel clensing purification . God Bless. keep healthy.
    Mr josh.

    • It’s only my opinion, but I think what you are doing is the best thing you can do in treating cancer: that is, take a strong decarbolylated THC dose at night and a blend of THC and CBD during the day. There is new research that is showing that CBD is strongly anti-cancer. And we know that THC kills cancer as it pairs with the CB1 receptor. So you have the perfect cocktail for healing. Best of luck. ~Dennis

    • Hello, Im Mr Josh and i would like to request a favor from you. I mistakenly left my telephone number. Can i have it removed?
      I am now starting to get calls from folks wishing to buy oil from me.
      I cannot make the oil for anyone because it is highly illegal I did not mean that i would be supplying oil for anyone. You have to make your own or get it at a dispensary. If you are making oil and trying to sell it to folks you are leaving yourself open for some serious legal problems. You also should know everything and anything current on how to make this medicine. In the end we will have to work for legalization and stay within the limits of the law. We have to change the laws. Stay healthy, dont hate, stay hopeful. Learn as much as you can .

    • Hi Nat – if you have a question you can post it here; as it may help someone with a similar issue. If not, you can leave your email address and I can contact you. ~Dennis

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    • As far as I know,1:1 cannabis extract is effective in brain tumor treatment, and the cannabinoid chemistry does not compromise steroid use. If I had a brain tumor, RSO is exactly what I would do. ~Dennis

      • Hi Dennis! Could you please tell me if tumors have receptors? I have seen someone’s statement saying that the most aggressive tumors have receptors which could connect with the cannabinoids and the slow growing ones doesn’t. Is there any truth in this? Thank you Dennis…


        • My understanding is that cancer cells have CB-1 and CB-2 receptors that pair with cannabinoids, regardless of the aggressiveness of the cancer. ~Dennis

    • No way to know until you try it. However, it’s good to know that current research is clear that cannabis is neuroprotective, and it is safer than aspirin. The exocannabinoids in cannabis have exactly the same effect as the body’s own endocannabinoids; they are mimetic. Endocannabinoids circulate constantly in the body; we even find endocannabinoids in mother’s milk. You might also know that cannabis has been shown to be therapeutic in seizure disorders, in children and adults. I hope this is enough information for you to proceed intelligently. ~Dennis

  93. Hi Dennis I am moving to San fransisco Bay, I see from the link above there are lots of dispensaries in the area but do they do the actual oil you are referring to or would I have to make my own, I am completely new to all this and do not have an idea what to do I would be worried it was not decarboxylated or 1:1 cannabis extract. I also read recently that as of 01/12/2014 you will not need a medical card but I will be applying for one. Can you offer any advice?

    • The potheads are not going to know anything about medical cannabis, so you have to ask for exactly what you want. Use the phrase “Rick Simpson Oil,” there should be no confusion about that. 1:1 is also uncommon, usually labeled as “high CBD.” The Omrita strain has a nice balance of THC and CBD. Also confirm decarboxylation if you are using it for treating cancer. There are many resources in the Bay Area, but be sure to stop in at Oakland’s Harborside Health Center; they are mostly well informed. Perhaps you could even get your card there. ~Dennis

    • Take with you any records you have that show that you are under medical care for any of the disorders allowable for medical cannabis.

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  95. Hi Dennis – Thanks for all your good work! What are your thoughts on using suppositories? I have prostate cancer and someone suggested that it just makes sense to get the meds close to the problem. I’ll be using a 39.6%THC / 32.2% CBD oil and I’ll blend it with cacao oil. I’d rather not replace my current sub lingual method with suppositories; but I’ll do it if the efficacy is increased substantially. Any feedback … much appreciated,

    • Jim – Suppositories work just fine; but it is exactly the same mechanism as sublingual: the active ingredients are easily absorbed in the buccal mucosa as well as colon mucosa. You choose, it really doesn’t make any difference. The cannabinoids have to traverse the circulatory system no matter where they originate. ~Dennis

      • Thanks Dennis – That’s a huge relief, but a double edged sword too! I’ve been doing sublingual and a rather big down side is swelling and soars on my tongue. Not unbearable, but not pleasant. At the same time I was really NOT looking forward to the suppository route! Since you are a biochemist I trust your take on this (the fact … “cannabinoids have to traverse the circulatory system … “) But isn’t it interesting that I’ve had several researchers in the field tell me that suppositories WOULD be more beneficial; to get the medicine close to where it’s needed. But if it has to travel the circulatory route, it’s no closer in reality! I suppose it’s a case of what appears logical is not the truth! Thanks for your reply Dennis


        • Jim – To avoid the mouth problem, when I was taking the oil, I would put it into capsules and take with food. Cannabinoids are not degraded in the liver, it just takes longer to feel the effect. There is no clinically significant benefit to sublingual, as opposed to oral; as far as I know. It is just faster; but what is the hurry? ~Dennis

      • Dennis? I’m wondering about this, as I heard Dr Donald Abrams say that he thought perhaps smoking cannabis would be a better route of administration for folks with lung cancer: it would get the medicine straight to the affected tissue. Is this possible?

        • Admin – True, vaporizing will take the therapeutics directly to the lung cancer. You might also remember that in the early work with brain cancer, the researchers injected extract directly into the tumors. How’s that for direct? There are certainly situations where direct administration works better than oral; and the opposite can be true as well. We just have to be intelligent how we use this healing herb. ~Dennis

          • So, there is something unique to Prostate cancer, where direct administration would not be effective, though with Brain and Lung cancers, it would be? (And, by the way, Dr Abrams said “smoking” rather than vaporizing, if memory serves. But it does seem vaporizing would have the same benefits.)

            • Admin – We normally do not see injections of cannabis extract into the prostate because it is more convenient to medicate orally (imagine injecting your prostate every day). In another vein, smoking cannabis is a terrible waste; setting fire to the cannabis incinerates the cannabinoids with very little medical benefit. Vaping, on the other hand, preserves the cannabinoids for a safe delivery to the lungs. Dr. Abrams must know this. ~Dennis

  96. Hi once again Dennis— and ‘gang’. I have followed comments on this blog for over a year now– including several posts relating to my OWN situation. I can relate to those of you who have become frustrated with the protocol for the treatment of prostate cancer. As has been pointed out– it will take a lot of time, patience and hard work before there can any type of generalized protocol. In my own case, however, I’m somewhat worried that ‘time’ is running out for me. It will have been 9 years ago come this March when I was diagnosed with prostate cancer (stage 2, Gleason 6 with my latest PSA being 23.6– having started at 5.7 when first diagnosed with a biopsy (a TERRIBLE procedure for me that I will NEVER do again).

    After being encouraged by 3 urologist (including 2 from the Mayo Clinic) to have surgery– I decided to take a month or so to do my OWN research on prostate cancer. I used books and internet and talking to people directly. Long before my month was gone– I had come to a VERY strong conclusion that the 3 pronged approach that the medical community offers– is — for the most part– a racket. This is NOT to say that there has NEVER been a time/place/situation that the medical approach had NOT been helpful– but that % is SOOOO low it would almost be like making a half-court shot in basketball (I’m a former basketball coach).

    Virtually EVERY hospital in the U.S. has a VERY large and VERY visible building– exclusively for cancer patients. Do we have ANY idea of how much MONEY is generated by the ‘treatment’ of cancer is this country (and others– but we are BY FAR the worst). When I was doing intravenous Vit. C for almost a year– I came to my local “cancer center”. This simple procedure involves about $2 worth of Vit. C and the apparatus used costs less than $5. Do you even want to GUESS what the hospital charged me??
    To go 3 times per week cost over $2000. This alternative treatment- was first proposed by Pauling (Nobel prize winner) over 20 years ago. O single 2 hour procedure that involved the injection of large amounts of Vit. C. Naturally insurance does not pay for THIS procedure, even though it stabilized my PSA for almost a year, I HAD to discontinue because I simply ran out of money. I have also been to Mexico (Hoxey) and tried going Vegan and also vegetarian.
    Most recently, I spent a good chunk of change (over $10,000) on RSO, which I’ve tried three times so far– including oral, sublingual and/or suppositories. For whatever reasons, after about a month my body just seemed to shut down. No appetite (I have lost as much as 30 pounds. At 6ft and a normal weight of 170lbs. I was sitting at 140lbs. My wife said I looked like a skeleton.
    I’m becoming concerned of late that my cancer MIGHT have spread. I’m wondering if there is ANYONE out there (including Dennis) that can tell me what the physical symptoms are that cancer has spread to the bones and/or other organs. I have recently talked to a friend of a friend, who currently lives in Peru where he has been studying for several years to become a shaman. It is a ‘spiritual’ approach to healing that involves the use of what is called “ayahausca” a unique plant. The ‘theory’ is that certain people that have physical ailments have a psychological rather than a physical origin and that until the psychological work is done– physical healing will NOT occur. I’m preparing for a trip to Peru on my 9 year anniversary of my diagnosis.

    I also wanted to make a quick comment about the use of suppositories. When I used them (homemade from coconut oil)– I WAS able to take quite large doses (close to a gram). However, I started to doubt the efficacy of this procedure because there seemed to be NO EFFECT (+ or -) After approx. 3 months I took another PSA and it was still 23.6 and my physical symptoms were no better. I’ve also been taking a capsule of CBD (Dixie Botanicals) every day for about 2 months.
    If there is anyone out there who MIGHT be able to shed some light on my experience as it relates to yours. I wish there was a way that we could have some kind of ‘conference’ on all this ‘stuff’ .As a retired science teacher–I’ve been able to follow the science behind the use of cannabis fairly well, but for whatever reasons — so far–the results have been very disappointing.I have 2 daughters that live in Denver but I live in Iowa. I’m willing to travel to get ‘help’. The only problem is– financially I’m not sitting very well. The medical establishment, along with Big Pharm and Big Insurance KNOW they have us –quite literally– “by the balls” .
    I just don’t get it– how this can be happening– almost right out in the open– and — with our government doing it’s best to support and protect — NOT it’s citizens– but the medical, pharmaceutical and insurance ‘establishments’.
    I have a brother who is a medical doctor— who is getting close to retirement. He — like most who decide get into this profession is a caring concerned soul– but his training is VERY limited in its focus and depth.
    Well– I’ve gone on long enough. I hope there might be someone out there who can shed some light on my situation. Thanks to all– and especially Dennis.


    • Hi Rod,
      In answer to the cancer spreading question. You may not know about it for many months, in many cases there are no symptoms for a while. Its always best to try and catch it before it spreads. With regards to the oil I’m starting to have my doubts about the whole thing.The re are to many variableseg trains, amount used, preparation methof, the lack of crebile anecdotes. it would be an interesting prtoject to gather all the email addresses in this blog to see if people actually got hold of the oil and whether it worked for them. i’m guesssing it did not or they would have come back to encourage others. Even manual guzmans brain cancer trail , all patients died within a year. If it did work there would be thousdands of online stories not a handful of lucky exceptions. (I’m
      also stating to read quite oa few of these stories online(mainly ion blogs

  97. Hey, Dennis. Nice to see you’re doing great and beating this a second time. Just some info to pass on, may mean something, may not. In a mason jar, about a half a pound of medicine not extracted yet. Sits in mason jars from Fall 2012 to August 2013. Initially, each jar of medicine was “burped”, opened for a few minutes, then closed back up. After a month of this, jars are then only burped once a month. The strains, AK-47, Northern Lights x Romulan, Hindu Kush, and Afghani. Entire this is being done, the jars are kept in cool, damp closet in pure darkness. When August 2013 comes, have enough Iso alcohol to extract. Heat the weed, or I believe it is known as decarboxylated at very low temperatures at around 200 F between 20 – 30 miniutes. Then I extracted. Now I have no idea if letting it sit for all those months changed something drastically but I have NEVER seen the extraction come out dark ORANGE. I did two initial washes, a third wash done later provided similar results with little green whatsoever. Burned off everything in a rice cooker, let sit, evaporate. The end result was the honey colour, but that orange effect was there. Anyway, after taking it, I was able to take way more with hardly any of that intense high I’ve gotten in the past, I’d assume the THC died off turning into CBN? But here’s the really great news, whereas before, previous extractions worked great, there was a limit I could take in due to the intense high, and though the pain of MS was gone, it didn’t last as long as this particular ORANGE batch did. We’re talking all day now with the ORANGE batch, however, taking lots of it still makes one sleepy for bed time. But the results are way better. Anyone I have spoken to never heard of it coming out such a deep orange, wonder what it the washing is drawing out, or has the chlorophyll somehow faded off, allowing the ISo alcohol to draw more of the resin which we know is honey coloured? Whatever the reason, way more effective, no pain whatsoever, functioning better than ever. Like a healthy person. Doctor told me anyone of any age would want results like this. Some more findings to share via old school strains that are widely available to us who have no access to the Cali clones coming up. Happy New Year, Dennis and all.

  98. Another thing, medicine is grown until late fall, the weather is very cold here in the Maritimes, at that point. We’re talking first week of October first harvest of plants, just their ripened tops, leaving remainder to ripen if possible until October 31 before hunters find them, Do my best to make sure trichomes are mostly amber before harvesting, a kid’s toy Eyeclops is perfect for seeing the trichomes. I am sure there are better options, but it’s a very effective one. I find the cold either puts them in panic mode, or they simply love it, but they fatten up and trichome production is insane when the weather gets colder.

    A strain widely available again, who knows if the versions are true to the version I have, the strain: C-99. My fav strain, after the MTF strain. C-99, being a mostly sativa strain, is a great day time strain, one can be highly functional on it, takes away pain, gives one energy, and lasts quite a long time. It is better grown indoors, as the flowers remain compact, outdoors it spreads, but the yield is about the same, but for some reason find the outdoor medicine extracted more effective. Sun?

    Some very effective widely available indica or mostly indica strains: Romulan, Northern Lights or Northern Lights #5(do research before buying, some are horrible verisons), BC Hashplant or just plain ole Hashplant is highly effective strain, Hindu Kush, and of course Blueberry. Dozens of others, but these strains have effective medicine in them for those who cannot obtain the highly coveted clone-only Cali strains.

    If someone is looking to make seeds, seeds that are true to the mother plant, then I recommend IBL (in bred line) or landrace strains. The IBL strains: C99 (if Joeyweed or Grimms’s version or if someone states it’s from those lines), AK-47, White Widow (though the line is slowly dying off, hard to get a good version now), Herijuana, Skunk #1, Afghani #1, the MTF version I have, Blueberry, Hindu Kush (some argue it’s landrace, doesn’t matter, seeds are true), BC Hashplant. Some Landrace strains, which for those who don’t know, are strains that are not hybrids, and have grown naturally for millenniums. The best Indica strains from my experience are: Mazar-I-Sharif –which is an impressive, greasy, full of trichomes strain that is very hardy and handles a few bouts with snow, I kid you not. It is also higher in CBD but nothing like those cali strains, but some of us have to work with what is available to us. More: Malana Cream. Tajikistan. Okay, the Landrace Sativas. Only have grown two successfully here in this cold climate, Santa Marta Columbian Gold, and Manga Rosa. Now, The Columbian Cold handled the cold weather no problem and yielded good medicine. Whereas Manga Rosa is better suited for those in warmer climates, and forget growing this wild Sativa indoors, unless you are growing in a huge warehouse.

    I have never lit a joint in my life so I have no idea what kind of smoke any of the above make, to me, it’s about the ingesting, and rubbing on sunburns (very effective! mix with coconut oil) or wounds. Hopefully my posts have been of some help to those who are wondering what to get. I know when I first went looking for information on what kind of strains to get, no one had the answers, and not even Rick Simpson would really say, for the exception of him mentioning White Widow as his choice, but so many rip-off crappy versions of that strain. And I get that, it’s hard to say what will work for who, and comes down to growing methods, environmental factors, indoor or out etc . . . But above, those strains were kind to me and have no complaints. No doubt there are way better strains, and implore those who feel that way to share, so others don’t have to go through all that I did to get decent medicine.

    Good luck everyone, and a Happy Healing New Year for every one. If I think of anything else, I will post back. Ask me anything, I will answer as best as I can. I am far from a pro, just a dude who has witnessed the miracles of this plant (two diabetic friends no longer take insulin thanks to it) and as well it has given my life back.

  99. Oh, one other thing, two years ago, I had some stuff that was “washed” three times, that being I extracted the plant matter twice, with Iso alcohol, it’s all I have available for solvent. Anyway, I wondered if there was anything left in there for medicine. So I decided to put the already ground up plant matter, a mix of pure flower and shake (leaves, small buds, stem, even male plants), and put it in a crockpot with iso. Left in there for about five hours. You can imagine how gross looking the stuff was and how horrible smelling the final product was. Now, it tasted even worse. Oh my god, it was horrible tasting. No high, but it did take my pain away. I did mix it with some coconut oil, planning on just using it for topical. But I got cocky and decided to take a teaspoon of it, thinking there was nothing left in it. Well, I had quite a trip. Hallucinated, panic attack, the points: Don’t be cocky. lol And there is still untapped medicine in that plant after three washes. This is truly an amazing plant.

  100. Dear Dennis Thank you for your dedication, and your compassion.
    I just have one question that has been perturbing me. Since i was diagnosed with late stage prostate cancer I have had two three psa tests. the first one was a year and a half ago.. It was 800 Well i got on the Gerson therapy and started doing everything that it called for. I treated it like Ive treated all degenerative disease. Supplementation, Purification exercises, organic fruit juicing, unpackaged foods. The Hoxey formula, ozone insufflations. and lots of rest and meditation. Despite all the modalities I was using my psa came back last month at 1500!I YIKES! I make some great oil and started taking it about three months ago. THC 8% to 17% CBD for daytime. the night time oil has tested 48% to 1.5% CBD. A total of one gram a day.
    The really crazy thing about all this is that I have been watching my blood tests very closely, the thing is that all my test signs blood, urine, blarubin kidney function, everything seems to be ok when i get tested
    My general health is ok. but i found that heavy work just poops me out. I look great after 12noon tho. WHY THE STILL HIGH PSA? All in all I have been looking pretty good lately. clear eyes, skin, sleeping ok./
    My theory is that because the body uses inflammation to kill disease. I might just be using too many modalities. All those macromolecules, dead cancer cells etc. are flooding out of my liver at a pretty heavy rate. I am taking the oil and have cut back on the Hoxey, and the daily rectal insufflations, I am going for my next cbc blood panel next month. I will be praying that this next test is much much lower. Whatever happens, I,m on it and believe in my heart that once the liver has been regenerated, the rest of the body will follow. Wish me luck . take it easy., but take it. Kill your cancer with everything healthy. Dont believe in any magic bullets. use whatever organic energy modalities you can find. Keep calm with meditation .
    Peace and good health to all beings.

    Mr JOSH
    PS It is common medical knowledge that when your “flight or fight” response kicks in from fear of being harmed it almost completely shut down all the energy to your immune system. So stress cripples your chances of beating degenerative disease.

    • Mr. Josh – PSA is a measure of inflammation at the prostate. It is not necessarily an indicator of cancer, although cancer is inflammatory. If you have inflammation in your body, you can expect PSA to be elevated. ~Dennis

  101. Thank you so much Dennis. I really appreciate the way in which you try to respond to all of us. God Bless. I’ll let you know about the blood tests.

  102. Hi Dennis – Jim here again. I just want to confirm (beyond a doubt if that’s possible!) that there is no clinical advantage in using oil suppositories for prostate cancer. As opposed to sub-lingual or just eating. You did already answer this! … but with the caveat, “As far as I know.” The reason I’m pushing this is that I’ve had a very knowledgeable person raise the issue of “getting the meds close to the problem.” Rick Simpson also says there is an added benefit? Or at least a different effect. So can you say unequivocally that the medication would have to travel the exact same route to arrive at the cancerous cells? Hence NO advantage to suppositories?
    Thanks Dennis for your considered feedback. (*I don’t mean to be rude or to doubt you! … just want to be sure I get the most out of the last of my oil)
    all the best,

  103. Dennis – here’s a PS to the previous submission.
    Dr. Jeffrey Hergenrather (from Northern California) wrote this to me in an email:

    “Hi Jim,
    For prostate cancer, we have patients reporting the use of oil compounded with theobroma cacao (cacao butter) and taken as a suppository. This puts the medicine close to the cancer.”

    Dr. Hergenrather is very well respected in the field. I’d really like to clear this up … to use suppositories or not; so I can get the maximum benefit from the limited oil I have left (remember I’m here down under in Oz where we haven’t quite seen the light yet!)
    Thanks Dennis,

    • Jim – I’ve never used suppositories, only the oil orally; so based on my experience I just do not know which is most efficacious. If you trust your doctor, follow his advice. Either way cannabis kills cancer. Either choice you make will kill the cancer, so do what feels right to you. It is very important that you follow the path where you are most confident. That count for a lot. ~Dennis

  104. I hope this helps you. I make up strong canna butter and i just take a syringe and shoot a gram about 4 inches in. I find it increases the amount of strength of the treatment ,but as I have mentioned before,and as Dennis says above, use as many modalities as you know will help . Just remember to keep your gallbladder clean by doing the liver gallbladder flush used by the Lahey Clinic in Boston Mass. Otherwise you can get jaundice and havet to go the hospital. Again, I really believe that coffee enemas keep the bile flowing and on track. The more you kill,the more you dump. The more you dump the dead stuff out of you , the less nauseous you feel, the more your immune system has a chance to come back. Peace and health to all beings. Mr Josh

  105. Pingback: Marijuana Question - Page 2

  106. Hello Dennis. Hope you are ok and everything is good with you. I was really starting to gain energy, blood all good, eyes bright. Then I hit the wall because the great oil , the gerson therapy, and the hoxey Tonic started bringing more metabolites and dead cancer cells out of my body than my stomach could stand. I have not been eating much because of my nausea. and vomiting. This is a clinically good sign, because most of the Gerson patients livers all take them to the same place .a flare up. Now I have to take some time to treat my stomach all those organic. juices and enemas and the oil I’ took a gram a day really released some toxins . I have lost about 20 small tumors in my stomach , I was really starting to look and feel tons better. Any way my best friend invited me to Maui for his wedding. Just a week before my flying my ozone generator died on me. No time to order a new one had to leave. Got there , drank beer, had some ice cream and cake, ate stuff I never eat anymore. Consequently, I kept eating at the wedding and on the way home in the plane vowed to get straight with my diet that day. But this was my best friend of 30 years. I did not get time to order another ozone generator until last week. So, I was without my every day treatments of rectal insufflated ozone for about month. ! I called up my doctor in Mexico and I asked him what was happening. He said that because my blood looked so good before my eating problem. It might have been a bad test. He asked me if I had been working and I told him that yes when I felt good I would drive to the shows and do them. This was a mistake , but I felt so good. I confessed that I did not take my ovatrophin (a testosterone suppressor) I got confused somewhere along the line and stopped taking it as much as I should have. Im taking it now. HERE IS MY MAIN QUESTION. Is LUPRON without adverse side effects? I understand you took it.
    Everyone I know was congratulating my recovery. Then my stomach just quit digesting , and my appetite started slipping, I had to go to camomile enemas and I lost 24 pounds. I stopped taking the oil by mouth and now am shooting it up my butt . Now, what I told my doctor from Mexico was that I thought that because of the loss of my potent ozone treatment, my carrying on too much at the wedding, Working at large music amphitheater those 13 odd days last summer might have been part of the problem. Anyway, I am slowly getting my gut back by drinking plenty of peppermint tea. and taking my plenty of rest. I am feeling better today. There is a great deal to be said about being carful to not develop a cocky attitude about what a great healer you are. What I feel is that there will never be a magic bullet that will do everything for you. This is not saying that I am not still crazy in love with my oil and the many divine , and miraculous benefits that come from that sweet de-carboxalated calling card from God. I just want to say that I still have tons of faith in alternative methods of healing, but there is always the chance that you might miss something if you think you have all the answers. I love oil, The Gerson therapy , Humidified Ozone application, Daily Purification of all the fluids and cells of the body along with a deep respect for the fact that our whole planet has been irreversibly polluted, and we really have no choice,we had better watch our health. The huge packaged food corporations feed us crap that gives our kids cancer. The FDA, still does very little to protect us from all of it. Before I go to work my ass off on saving my own life and do my third enema today I would just like to thank you again for all your help. Im gonna go and gratefully make another three months worth. Be strong, work for you healing with more than just one hand. Change your lifestyle to a sugarless, low fat organic life saving way to live. God all. Your faithful and fellow sufferer , Mr JOsh.

    • Lupron is an androgen inhibitor used to slow the growth of cancer that needs androgen to grow. The effects are what you would expect having no testosterone. I didn’t mind taking it at all, in fact it was interesting seeing what like is like with no testosterone. Do a google search for lupron side effects. ~Dennis

  107. *NOTE: I’ve sent this as an email to several reputable researchers into medical cannabis. Dennis It would be great to have your take on this question.

    Hello from ‘down under!’
    I really appreciate the time some of you have given me in answering my questions. Now I think I’ve found the most interesting and important question so far!

    I’ve just started reading Martin Lee’s book Smoke Signals and a passage regarding dosage levels jumped out at me. I’ve been trying to get specific dosages for my particular prostate cancer. (Gleeson score 9 / Stage 4 with minimal spread to bladder and seminal vesicles) Finding dosage specific research or results has proven illusive: I imagine that’s probably because the “Science” is in its infancy.

    Rick Simpson and others advise working up to a huge dose of 1 gm. per day. I’m now using a 39.2 / 32.2 THC/CBD oil at daily doses (perhaps 4 – 6 times) cumulatively as low as 0.1 or 0.15 gm. – this dosage has me getting as “high” as is comfortable; so I can’t imagine taking in a gram at once – I think it might bring on a state of paralysis! (*maybe I just have a very, very low tolerance?)

    To the point: When I found this passage in Smoke Signals I hoped that this early research might hold water today. I could avoid the ‘too stoned’ business, and at the same time save money using a lot less oil!

    “One of the curious characteristics of this “powerful and valuable substance,” O’Shaughnessy observed, was the ‘contrary qualities’ of medical hemp, “its stimulant and sedative effects.” He found that hemp “possessed in small doses an extraordinary power of stimulating the digestive organs [and] exciting the cerebral system,” while “larger doses induce insensibility or act as a powerful sedative.” O’Shaughnessy expressed concern that “the incautious use of hemp preparations” could trigger “a peculiar form of delirium.” Too strong a dose, he warned, might produce just the opposite of the desired medicinal. outcome. The concluding sentence of his seminal study advised: “My experience would lead me to prefer small [emphasis in the original] doses of the remedy in order to excite rather than narcotise the patient.”
    O’Shaughnessy was describing what would become known in modern pharmacological parlance as the “biphasic” effect, whereby smaller amounts of a particular substance pack a potent therapeutic punch while larger doses have the opposite effect….

    So far in the limited research I’ve done; I haven’t seen – even once! – this minimal dosage theory applied to cannabis oil, in treating cancer. Why? Is O’Shaughnessy’s research totally dated? Are there some people who believe that it’s valid? Might this ‘biphasic’ effect apply only for certain conditions?

    I’d really appreciate any light you can shed.
    Thanks very much,

    Jim Migdoll

    • Jim – It is important to gradually increase the dose as you become acclimated to the medicine. You can take a large dose at bed time and sleep through the high; and take a moderate dose during the day. Also taking ibuprofen knocks down the high and eliminates memory loss. Google THC+ibuprofen and you will see the science about it. You can also increase the CBD as that also kills the high of THC; but does not inhibit the therapeutic benefit of THC. Lastly, I have no idea about the biphasics of O’Shaughnessy. ~Dennis

  108. Dear Dennis. As always, Thank you for your knowledge.This is Mr Josh. I am doing much better again . I hit a wall with the Gerson therapy two weeks ago. Could not eat. Too much alkyline bile got into my upper GI causing belching, gas nausea and vomiting in the morning. I understand that people who take more oil then they can handle experience the same thing sometimes. What I do is stop any coffee enemas I’m doing, and switch to using chamomile tea. Also drinking quarts of peppermint tea each day. There is also a product on the market called SEROVA, which is made from concentrated aloe vera. It is fantastic followed up with a good probiotic to daily REPLACE THE NATURAL FLORA of your stomach you lose whether your cleaning out with daily coffee enemas , or using really strong hits of oil. I could not eat a bite or drink an organic carrot juice for a good 2 weeks. When you dont eat , you dont heal. I lost about 27 pounds in two weeks. Doing the juices saves you because they give you more than the adequate daily dosage of vitamins, enzymes and minerals.
    The Gerson therapy is a wonderful addition to any healing modality
    but , as I always say there are very few magic bullets, that work better than a combined attack with good nutrition, oil, ozone,and anything else that works naturally with no harm to healthy cells.
    This is a very ancient Sanskrit prayer to say when you are taking your medicine ‘OM,SIVA CHAN KAR RA HURRY HURR GANJA!
    “Thank God for all this sacred medicine.”

  109. Dear Dennis,

    Thank you so much for sharing your knowledge and experience. My mother has Stage IV lung cancer, adenocarcinoma. She went through three and a half weeks of the seven weeks of Intensity Modulated Radiation Therapy, but ended up having fluid in her lungs which had to be drained and found to be malignant. Last Wednesday the doctors told her no more could be done. Thank you for giving me hope.

    I realize that everyone must go sometime, but this is beyond awful. A month ago (she was Stage III then), she was walking her dog and today she has difficulty walking. She barely eats – she was tiny already, but she’s dropped to 67 lbs (less than my 8 year old). She has difficulty breathing and has swollen feet and legs. She is extraordinarily tired and weak.

    We live in Arizona, and tonight I applied for an AZ Medical Marijuana card for her. I to give her Rick Simpson oil. I see that you recommend 1:1 THC:CBD. I do not know if there is a place in AZ that sells that, so I am thinking I may need to make it.

    First do you know of any reputable dispensaries in Arizona that sell Rick Simpson oil? Second, if I cannot find the oil and make it, what strain(s) would you recommend to get the 1:1 THC:CBD content. Someone recommended I purchase “trim” from a delivery truck, but I thought I had read that buds were needed. If you could advise me in any way, or direct me to someone locally in the Phoenix metropolitan area, I would greatly appreciate it.

    Thank you so much.

    • Sheila – I recommend 1:1 because both THC and CBD have been shown to be effective anti-cancer agents, through different biochemical pathways; they are complimentary. Nice if you can find a strain of cannabis in this proportion. I like Omrita, but there are others. If you can’t find one of these “high CBD” strains, you can take them separately: for example, take the THC at night that will help with sleep, then get a high CBD tincture for daytime use, as it is non-psychoactive. Experiment to see what is best with what you have available. And yes, you have to have buds. If the buds are mixed with trim, then the extract might be rich in cannabis terpenes which are also beneficial. Sorry I do not know anything about the Arizona availability. Perhaps an Arizonan will see this and help. ~Dennis

  110. “The only thing necessary for the triumph of evil is for good
    men to do nothing.” Edmund Burke

    There is no doubt Cancer is evil. So thank you for spreading
    the word on this type of treatment. What i am attempting is
    to treat Pancreatic Cancer, that is either stage III or IV. I
    will find out the exact Diagnosis Friday January 31, 2014. I
    am able to obtain a liquid mix of:

    CBD %: 27.9
    THC %: 20.9
    THCA %: No
    CBD %: 1.03
    THC %: 57.4
    THCA %: No

    Do you know of anyone who has tried this treatment/protocol,
    for advanced Pancreatic Cancer. Any help will be greatly

    Thanks so much Dennis.


    Players, of course, have access to other painkillers, including prescription drugs. Yet as former Surgeon General Joycelyn Elders has argued, “marijuana is less toxic than many of the drugs that physicians prescribe every day.” As public opinion and state laws move away from strict prohibition, it’s reasonable for the N.F.L. to do the same and let its players deal with their injuries as they — and their private doctors — see fit.

  112. Can Cannabis tea work? I’ve used .5-1.0 gram a night, drunk the tea and eaten the remaining leaves/buds and had good progress reducing joint and muscle inflammation (likely caused by an auto-immune disorder caused by mercury leeching from fillings) and sometimes a significant psychotropic effect.

  113. Dear Dennis, my brother was told in Sept 2013 that he has bladder cancer. It is an aggressive type but has not invaded the muscle. He has had 2 surgeries to scrap the tumors. Next month they want to put the BCG in him or if they see more tumors they want to remove the entire bladder. He researched natural cures and 2 months ago he became part of a clinical trial using cannabis oil. One gram a day. Dennis, have you heard of anything else that will help my brother. Any advise you can give me would be so much appreciated. My brother is only 54. Never smoked or drank. Since this cancer, he has changed his diet to mainly fish, fruits and vegetables. Thank you so much Dennis for your time.

  114. Queen – Whoever designed the clinical study that your brother is in, knew exactly what to do. Gram a day of cannabis extract oil is right on. I don’t know anything better than that, along with the change in diet, this treatment protocol looks great. I have nothing to add to this. ~Dennis

    • For Queen, I’m of the understanding that the cannabis oil must be decarboxylated to be truly effective and not all providers may be aware of this.

    • Hello Dennis, first let me say I appreciate all your time and thoughts. my brother Chris found out today that there are 4 small superficial lesions on the bladder. Chris as been taking 1 gram canibous oil per day for 31 days, before that he took 1 to 2 drops per day for over 2 months.. The doctor told him that within one month he must remove the bladder if he sees anymore lesions. my question Dennis is: I heard that if you raise your PH level to at least 7, it will help alot. do you know of any thing that will raise that ph level? Chris is taking baking soda and drinks alot of lemmon water. any help would be so appreciated. thank you Dennis, my family sure loves you. take care. Queen Elvig.

      • Hello again Queen – Glad to hear that you have increased Chris’ dose from drops to grams; that is the most important thing to do to resolve the lesions. If you want to make his system more alkaline; try ginseng, it is the most alkaline food I know of. Best to you both – Dennis

        • THANK YOU DENNIS, Chris noticed that the canibous oil he was taking was rather dark, [mabe not very stong in strenth] he is now taking another batch that is more golden color. Hope this one works better. Thanks again Dennis for all your kind words. you are such a wonderful man! We appreciate and love you very much.


              “Mommy Lobby” for medical marijuana
              Mommy lobby’ emerges as a powerful advocate for medical marijuana for children

              View Photo Gallery — In family with daughter who has rare condition, marijuana offers hope: Born with a rare chromosomal disorder, 6-year-old Lydia Schaeffer suffers from life-threatening seizures that doctors haven’t been able to control despite countless medications. In marijuana, the family thinks they might have found a treatment that works. Now, they are trying to help legalize the drug.

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              By Ariana Eunjung Cha, E-mail the writer
              Standing in a Wisconsin State Capitol hearing room surrounded by parents hugging their seriously ill children, Sally Schaeffer began to cry as she talked about her daughter.

              Born with a rare chromosomal disorder, 6-year-old Lydia suffers from life-threatening seizures that doctors haven’t been able to control despite countless medications. The family’s last hope: medical marijuana.

              For some families with children who suffer from rare seizure disorders, a new form of medical marijuana is proving to be a life-changing treatment.
              For some families with children who suffer from rare seizure disorders, a new form of medical marijuana is proving to be a life-changing treatment.
              Despite warnings from the American Epilepsy Society, dozens of parents are flocking to Colorado for a rare strain of pot known as Charlotte’s Web.
              Despite warnings from the American Epilepsy Society, dozens of parents are flocking to Colorado for a rare strain of pot known as Charlotte’s Web.

              Schaeffer, 39, didn’t just ask lawmakers to legalize the drug. She begged.

              “If it was your child and you didn’t have options, what would you do?” she said during her testimony in Madison on Feb. 12.

              The representatives were so moved that they introduced a bipartisan bill to allow parents in situations similar to Schaeffer’s to use the drug on their children.

              Emboldened by stories circulated through Facebook, Twitter and the news media about children with seizure disorders who have been successfully treated with a special oil extract made from cannabis plants, mothers have become the new face of the medical marijuana movement.

              Similar scenes have been playing out in recent weeks in other states where medical marijuana remains illegal: Oklahoma, Florida, Georgia, Utah, New York, North Carolina, Alabama, Kentucky.

              The “mommy lobby” has been successful at opening the doors to legalizing marijuana — if only a crack, in some places — where others have failed. In the 1970s and ’80s, mothers were on the other side of the issue, successfully fending off efforts to decriminalize marijuana with heartbreaking stories about how their teenage children’s lives unraveled when they began to use the drug.

              Mothers have long been among the most powerful constituent groups in the United States, and the reason is clear. Groups such as Mothers Against Drunk Driving are able to draw so much public support because they tug at a universal human emotion: the desire to protect children from harm. And while national gun-control efforts after the Sandy Hook massacre faltered, mothers’ groups worked to keep the issue on the public radar, helping to get some new measures passed at the state level.

              Today, mothers are fighting for access to the drug, and they have changing public attitudes on their side. For the first time, a majority of Americans in opinion polls say they support the full legalization of marijuana.

              Last year, Colorado and Washington state made marijuana fully legal, and there has been a groundswell of support in several states for ballot initiatives or legislation to do the same, including some in the conservative South.

              Medical marijuana is now legal in 20 states and the District of Columbia. The diseases and conditions for which it can legally be used are limited and vary by jurisdiction. Most states have additional requirements for children: Instead of one prescription, parents must get two from different doctors.

              Even in states where marijuana is available for children, the mothers say it is often a challenge to convince physicians that the potential benefits outweigh the risks.

              The drug the mothers are seeking is an extract that contains only trace amounts of the part of the plant responsible for the euphoric effect of the drug but is still high in cannabidiol, or CBD — a substance that scientists think may quiet the electrical and chemical activity in the brain that causes seizures. Instead of leaves that are smoked, it is a liquid that is mixed in food or given to a child with a dropper.

              The prospect of treating large numbers of children with this substance has alarmed medical organizations and anti-drug groups that say the potential dangers of prescribing an untested and unregulated treatment for young children are being lost in the conversation.

              Little is known about the effects of marijuana on children; most studies have looked at teenagers who use it illicitly.

              Much of the concern centers on the developing brain: Marijuana use has been linked to higher rates of mental illness, including thought disorders, depression and anxiety, as well as — according to one prominent study published last year — diminished IQ over time.

              “There’s a lot of misinformation and emotion in this issue, rather than a focus on science,” said Kevin Sabet, an outspoken opponent of marijuana legalization who is director of the Drug Policy Institute at the University of Florida and was a former senior adviser for drug policy in the Obama administration.

              The epilepsy community is divided on the issue. The Epilepsy Foundation, which represents patients and their families, said in late February that it backs efforts to legalize medical marijuana for use in pediatric epilepsy patients. But the American Epilepsy Society, which represents physicians and other professionals working in the field of epilepsy, says the treatment “may not be advisable due to lack of information on safety and efficacy.”

              Sharon Levy, an assistant professor of pediatrics at Harvard Medical School and chair of the American Academy of Pediatrics committee on substance abuse, said she’s a strong proponent of studying and developing medications from the active ingredients in marijuana. But she does not support the idea of parents choosing the plant they think would be best, making their own oral preparations and guessing at proper dosage without knowing long-term side effects.

              “It is a bad idea. When I look at the accumulation of studies about marijuana and children, I am very concerned,” she said.

              Levy said she understands that efforts to develop and test marijuana-­based treatments for the disorder may not be moving fast enough for some children with severe epilepsy. But she said that the fact that there are flaws with the regulatory system means that we should fix the system rather than bypass it.

              “We shouldn’t forget that the regulatory system was put in place for a reason,” Levy said. “The history of medicine is littered with stories of ‘medications’ that had terrible long-term impacts.”

              Charlotte’s story

              Stories about the promise of marijuana for seizures have been circulating as far back as the 19th century, but it wasn’t until two years ago, when Paige Figi, a Colorado mom, began posting online stories about her child’s experiences with the treatment, that other families began to take notice.

              Of the 2.3 million Americans living with epilepsy, more than 1 million of them have seizures that can’t be controlled by modern medicine. Figi’s daughter, Charlotte, was one of them.

              Diagnosed with a rare condition called the condition known as Dravet syndrome, Charlotte, then 5, was suffering from more than 300 seizures each week. She used a wheelchair, could only say a few words and had gone into cardiac arrest more than once. Desperate after doctors told them there was nothing more they could do, Figi and her husband, Matt, turned to medical marijuana.

              They began to give Charlotte a few drops of an extract made from a strain of marijuana that was high in CBD, which is thought to be medicinal, and low in THC, the component that creates a high, twice a day with her food. They were surprised when the seizures nearly stopped.

              As Charlotte’s miraculous story spread, more than 100 families relocated to Colorado Springs, where the dispensary selling the substance is located. Across the country, parents are holding bake sales, benefit concerts and other fundraisers to try to raise money for the treatment; it can cost several hundred dollars a month to purchase the extract. A nonprofit foundation formed to assist those seeking the drug said that 187 pediatric patients are being treated and that there is a waiting list of more than 3,000.

              Figi and Joshua Stanley, the grower who co-created the strain that is being used in the treatment — now known as “Charlotte’s Web” — have become heroes in the epilepsy community.

              At the invitation of mothers, Figi and Stanley have been traveling around the country, telling Charlotte’s story to lawmakers in other states.

              “It’s very emotional,” Figi said of the hearings. “Everyone’s handing out tissues — especially when someone comes who has lost a child to seizures, and they are coming out to support this effort.”

              Stanley, 38, runs the Stanley Brothers, one of Colorado’s biggest growers, with five of his brothers. He recently started Strains of Hope, a nonprofit organization that is dedicated to trying to get governments around the world to legalize the use of marijuana for medical purposes. As a first step, he said he is working with partners in Jamaica, where he hopes the extract could be available for free to children who need it as soon as the end of this year.

              “Children should not be dying because of these antiquated laws,” he said.

              But beyond all the heartbreak and hope lies the question of whether the treatment works. And if so, how?

              Stanley declined to release any detailed numbers about how effective the treatment has been, but he said nearly every child with epilepsy who took the extract experienced a reduction in seizures.

              There is some medical support for such a claim. There are several thousand published studies showing the potential benefits of marijuana for some conditions, and animal studies have shown that using CBD can stop seizures. Marijuana is made up of hundreds of components, with about 80 classified as cannabinoids unique to the plant, which scientists think activate specific receptors in the brain and other parts of the body to produce physiological and behavioral effects.

              Heather Jackson, executive director of a foundation that is dedicated to research, education and advocacy for Charlotte’s Web and other marijuana-derived medicines, said the organization has begun to communicate with partners about the possibility of starting clinical trials for the treatment.

              “We know that, in order for the treatment to be accepted by the medical community, there has be more testing, but because it’s marijuana, there has been a lot of red tape,” she said.

              GW Pharmaceuticals, a British company, received FDA approval in December to begin clinical trials of a medicinal form of marijuana for children with epilepsy at New York University’s Langone Medical Center, the University of California at San Francisco and other locations.

              But the trials are limited, and many mothers said they tried to enroll but were told the trials were full.

              Proposals for the future

              One of the first things Schaeffer told lawmakers when she stepped up to the podium in the hearing room in Madison was that she had never smoked marijuana. She wanted to make it clear that she wasn’t part of a more radical movement that aims to legalize recreational marijuana.

              Like many of the mothers involved, Schaeffer said she supports legalizing medical marijuana for everyone but would be happy with a narrow law that authorizes the use of a specific kind of marijuana treatment for children.

              Schaeffer’s daughter, Lydia, has a rare form of epilepsy that makes her have seizures when she sleeps. Doctors have told the family that the only treatment option is a surgical procedure that would remove part of her brain. They warned Schaeffer and her husband that such a treatment might end up leaving her more disabled — the surgery could blind her, for instance. Moving the whole family outside Wisconsin to a state where medical marijuana is legal is not an option, they said, because they own a small landscaping business in Burlington and Sally Schaeffer’s parents live nearby.

              She said that if the bill does not go through this session, she may move to Colorado with her daughter and her husband may have to stay behind with their two sons.

              “If I have to wait, I worry, what if my child doesn’t make it? It is heartbreaking to think of losing your child from a seizure when you know the medication is out there that could help them,” Schaeffer said.

              Wisconsin state assembly member David Murphy, a Republican, said he signed on to be a co-sponsor of the bill after hearing about the mothers’ plight.

              “I am not in support of legalizing marijuana and have not supported medical marijuana up to this point, but common sense tells me this is not remotely the same thing as that,” Murphy said.

              While the mothers have received almost universal sympathy wherever they go, the proposed solutions to their problems differ by state.

              In Wisconsin, the state committee on children and families passed a bill last week to allow the use of CBD oil in the treatment of seizure disorders. In Utah, state lawmakers have talked about importing the extract from Colorado and having the health department administer it as an herbal supplement.

              In New York, Gov. Andrew M. Cuomo (D) has proposed a plan to use existing law to allow 20 hospitals to dispense the drug.

              None of these are permanent solutions, the mothers say.

              Even those who live in one of the states that allow medical marijuana say there is a need for change.

              The main issue is that many parents think that only certain strains or formulations may work for their children, and, because marijuana is classified as a controlled substance, they can’t move the drugs across state lines — limiting not only their treatment options but medical research.

              “This is not how medical care is supposed to work in the United States. You shouldn’t have to watch your child suffering and be told you can’t have the medicine that can help because you live in the wrong state,” said Colleen Stice, 35, a former payroll manager in Tulsa who quit her job to take care of her 14-month-old son, Rowan, after he began to have seizures.

              She said she and her husband are ready to move to Colorado if legislation is not approved in Oklahoma, but she worries about what might happen if a different drug that works better is developed in another state. Would they pick up and move again?

              The only answer to this patchwork system of access to medical marijuana treatments, the mothers say, is federal intervention.

              They are asking the FDA to speed up the approval process for drugs based on CBD, requesting that the National Institutes of Health dedicate more money to this type of research and urging the Drug Enforcement Administration to reclassify marijuana so that it can be moved around more easily.

              This month, the mothers will bring their fight to Washington. Dozens are planning to fly in from across the country to meet with key legislators on Capitol Hill and hold a march across the city. They plan to bring their children.

              Magda Jean-Louis and Eddy Palanzo contributed to this report.

              More from The Washington Post:

              A brief history of public opinion on marijuana legalization in one chart

              The Lazarus Weed: The strange rise again of legalized pot

              Gallery: A tour of Colorado’s blossoming pot industry

              Advocates press for marijuana measure on D.C. ballot

              Md. lawmakers hear truth, fiction about marijuana

  115. Hi Dennis,
    I am in Australia where the oil and all cannabis products is illegal. My Dad is dieing of stage 4 glioblastoma in his brain. I want to get some cannabis oil but am worried when the hospital do their regular blood tests (as he is there indefinitely) it will show up and he’ll get kicked out. Do you know if the oil would show in a blood test? Thanks :-) Lauren

  116. Hon – When THC engages the CB1 receptor of a cancer cell, the number of CB1 receptors multiply, giving THC many more opportunities to stimulate Ceramide production to shred the mitochondria, thus killing the cancer cell. CBD kills cancer cells without interaction with any cannabinoid receptor. Although it does like the Vanelloid receptor. ~Dennis

    • U.S. Issues Marijuana Guidelines for Banks
      By SERGE F. KOVALESKIFEB. 14, 2014 NYT

      The Obama administration on Friday issued guidelines intended to give banks confidence that they will not be punished if they provide services to legitimate marijuana businesses in states that have legalized the medical or recreational use of the drug, even though it remains illicit under federal law.

      The guidance, which requires banks to vigorously monitor their marijuana-industry customers, was provided by the Treasury Department and the Justice Department in separate advisories. The policy does not grant immunity from prosecution or civil penalties to banks that serve legal marijuana businesses. But it directs prosecutors and regulators to give priority to cases only where financial institutions have failed to adhere to the guidance.

      Still, the banking industry was quick to say that the new guidelines would not be sufficient to make banks feel at ease about opening accounts for or granting loans to marijuana businesses because the drug would still be illegal under the federal Controlled Substances Act.

      “While we appreciate the efforts by the Department of Justice and FinCEN, guidance or regulation doesn’t alter the underlying challenge for banks,” Frank Keating, president of the American Bankers Association, said in a statement, referring to the Financial Crimes Enforcement Network, the Treasury unit that issued part of the guidelines. “As it stands, possession or distribution of marijuana violates federal law, and banks that provide support for those activities face the risk of prosecution and assorted sanctions.”

      Twenty states and the District of Columbia allow the use of marijuana for medical purposes, and two of those states, Colorado and Washington, have also legalized the recreational use of the drug. Those numbers may grow this year, as several other states are considering measures to legalize marijuana use.

      In a three-page memo to prosecutors issued in conjunction with the new banking guidelines, Deputy Attorney General James M. Cole wrote that prosecutions may not be “appropriate” when banks do business with marijuana entities that are operating legally under state law and do not violate any of the eight priorities set forth in a Justice Department memo last August. Those priorities include preventing the distribution of marijuana to minors and preventing revenue from the sale of marijuana from going to criminal enterprises.

      Jennifer Shasky Calvery, director of the Financial Crimes Enforcement Network, said she was unaware of any banks that have been punished for servicing legal marijuana businesses.

      Legal marijuana entrepreneurs have stressed that access to banking has been their most pressing concern. Their businesses are conducted almost entirely in cash, raising huge security concerns, because it is difficult for them to open and maintain bank accounts, or to accept credit cards. Banks have been apprehensive about providing services to marijuana businesses for fear that the authorities might punish them for violating money-laundering laws, among other federal statutes and regulations.

      Last month, Attorney General Eric H. Holder Jr. acknowledged that having so much cash on hand presented a public safety problem for legal marijuana businesses, adding that they should have access to the country’s banking system.

      Some representatives of the legal marijuana industry said that although the guidelines showed progress, federal laws need to be revamped.

      “It’s a great step in the right direction, but ultimately it would not solve all the problems here,” said Michael Elliott, executive director of the Medical Marijuana Industry Group in Colorado. “We need to go beyond saying that this is a low law enforcement priority. There are still violations of federal law going on here. So, federal laws need to be changed to ensure that what is legal in states like Colorado is legal at the federal level, as well.”

      Marijuana remains a Schedule 1 drug — along with heroin, LSD and Ecstasy — under the Controlled Substances Act. This week, 18 members of Congress, in a joint letter to President Obama, asked him to instruct Mr. Holder to remove marijuana from any of the drug schedules or to reschedule it to a lower category.

      “Classifying marijuana as Schedule 1 at the federal level perpetuates an unjust and irrational system,” the lawmakers, led by Representative Earl Blumenauer, Democrat of Oregon, said in the letter. “Schedule 1 recognizes no medical use, disregarding both medical evidence and the laws of nearly half of the states that have legalized medical marijuana.”

      Ms. Shasky Calvery said in a conference call with reporters that the guidelines should clarify how financial institutions can provide services to marijuana businesses while maintaining their obligation to comply with the federal anti-money-laundering law, the Bank Secrecy Act. She also said that the guidelines were drafted “to move from the shadows” the financial operations of marijuana businesses.

      The guidance “will provide transparency and mitigate the risks to the financial system,” Ms. Shasky Calvery said. The authorities do not intend to crack down on banks “for a technical mishap,” she said, adding: “We are not looking to have a gotcha enforcement regime.”

      In a seven-page document explaining the guidelines, FinCEN called for “due diligence” by financial institutions in monitoring their marijuana customers, including reviewing their applications for state licenses and understanding their “normal and expected activity,” such as the types of products they sell and whether they have medical or recreational customers.

      Since the financial transactions of a marijuana business are considered illegal under federal law, banks are required to file suspicious activity reports on those entities. A spokesman for the Treasury unit, Steve Hudak, said the reports under the guidelines would be abbreviated versions. Banks will have to initially file one suspicious activity report on a marijuana business, then three a year after that.

      The new guidelines also establish different kinds of suspicious activity reports, depending on whether a bank believes a marijuana business is running afoul of the Justice Department’s priorities or is violating state law.

      Matt Apuzzo contributed reporting.

  117. Hi Dennis, Did you pay attention to your pH, and how important is that for healing? Can’t seem to get my pH into the 7 range. Thanks Mavis

  118. Dennis, when treating cancer – how much oil on a daily basis does one need when treating cancer, and how does one figure that out? I have heard a general rule is 1 gram/day, however I recently was told that you needed to take 3 gms/day the second time around when your cancer came back.
    Thanks for all your help Dennis. I realize this is far from an exact science.

    • Mavis – Everyone has a different tolerance to the cannabis medicines, and over a broad range. One gram might not be enough for some, but too much for others. Start with one gram, see how well the patient tolerates the oil, then adjust accordingly. We increase our tolerance over time as we take the medicine, so we have to increase the dosage as our tolerance increases. In this inexact science we have to be vigilant to keep increasing our dose as the tolerance will allow. Potency varies widely so we have to adjust the dosage according to the patient’s tolerance. After the treatment phase is over, we need to continue a maintenance dose so it supports the immune system in keeping the spontaneous cancer cells down. Hope this is useful. ~Dennis

  119. Thanks Dennis Are you saying that once a person tolerates a specific dose (so they don’t get high), then they should increase the dose until they feel a high again?

    • Being high is a property of THC, tolerance means being able to function. If you want to avoid being high, use CBD; it is strongly anti-cancer and has no psychoactive properties. ~Dennis

      • So – the way I am understanding this is that during treatment, if one does not feel high any more with taking the 1 gram/day, the dosage should be increased until a high is felt, and so on?

        • Mavis – It’s just my opinion, but we are dealing with cancer here, we need to hit it hard to knock it down. I found it effective to take as much of the oil as I could tolerate during treatment. No doubt there are other opinions about this, but I was not lazy or fearful about taking the medicine. It worked for me. ~Dennis

  120. Dennis I hope you can help me unravel the vast amount of information on the amount and type of bud needed to make the oil. Currently, my daughter, who is Stage IV breast cancer with mets to her bones and stomach (tumor on outside of stomach lining) is taking the oil in a 1:1 ratio.. She goes to a dispensary in California for her oil, but would really like to make her own. So, which flower is going to give her the 1:1 ratio that she is using now and about how much should she buy to make the amount needed for the 90 day treatment? The website for the dispensary does not list prices for the flower. Would it be cost prohibitive to think about buying a pound of flower for this process? With so many confusing opinions out there, I sure hope you can offer some useful information.

    • Hi there, I’m sure Dennis will be along soon, and these note are for him (a reminder, though I’m sure he doesn’t need it)

      “In summary, we showed that CBD, a plant-derived cannabinoid, preferentially kills breast cancer cells by inducing ER stress, inhibiting mTOR signaling, enhancing ROS generation, and mediating a complex balance between autophagy and mitochondria-mediated apoptosis in MDA-MB-231 breast cancer cells. These findings support the continued exploration of CBD as an alternative agent for breast cancer treatment.

      When they exposed cells from this cancer to cannabidiol they were shocked to find the cells not only stopped acting ‘crazy’ but also returned to a healthy normal state.

      They discovered that the compound had turned off the overexpression of ID-1, stopping them from travelling to distant tissues. In other words, it keeps the cells more local and blocks their ability to metastasize. Cancer kills through its ability to metastasize.

      And somewhere in my research, there is support for a positive effect from the combination of THC and CBD, but can’t find it at the moment…

    • Rose – Encouraging to hear that your daughter is using the 1:1 THC:CBD. These two cannabinoids work synergistically to kill cancer. There is one strain I know of that gives nearly even potency: Omrita. This is considered to be a “high CBD” strain, even though it has the same amount of THC. There are other strains of high CBD cannabis, but I do not know the names. Check with your dispensary. I think that Harborside in Oakland has it, I don’t know which dispensary your daughter goes to. In making your own medicine you have two choices, 1) use all buds, 2) use the whole plant to extract the oil. Of course all buds will be the most potent and the most expensive. Whole plant is also good because it not only has the primary cannabinoids, but also has the terpenoids which are therapeutic. Whole plant is less potent, so you have to take more to approximate the all bud potency. Either choice will be good, depending on your resources. As you have observed, there are many opinions about all this, and this is only my opinion. Use your intuition about all this noise to make the right choices. I wish your daughter the best with her treatment. ~Dennis

  121. Hi Dennis, Please can you tell us what you think about taking an angiogenesis inhibitor (e.g. Avastin) with RSO. The reason for the question is that someone with Stage IV Colon Cancer (mets in lungs and liver), who has been taking the RSO for 4 months now, has not seen any positive results yet. The cancer was diagnosed a year ago, followed by 5 radiotherapy sessions, 9 rounds of chemo (which stopped in August 2013) and, currently, they are on just the angiogenesis inhibitor (Avastin, fortnightly). The CEA started at 144 a year ago, the chemo brought it down to 3.5, then, in the 6 months since the chemo was stopped in August (RSO was started in November) the CEA has climbed up to 54.

    The person has been taking a gram of RSO a day since the middle of November 2013, and, while there aren’t any new lesions, the existing ones continue to increase in size. Do you think that Avastin be interfering with the RSO?

    • Liz – The literature on Avastin suggests it is generally safe to use. If the patient has taken one gram daily of RSO for the last several months it would also be safe to increase the RSO to kill the cancers. ~Dennis

  122. Thank you Dennis. If I am not too effected by the oil at 1gr, can you suggest what would be a safe increase in dosage without getting too buzzed?

    Can I ask what you think about the Bob Beck protocol with the blood electrifier?

    • Liz – if you are not feeling the effect, then you are likely getting no benefit. Take as much as you can tolerate. Cannabis does no harm so you can increase the dose substantially. What I did that worked nicely was to take a large dose at night and sleep through the buzz. Then a smaller dose during the day to function. Sorry I do not know about Bob Beck blood electrifier. ~Dennis

    Weed Better (Excerpt)
    Marijuana itself is an anglicized corruption of mariguana or marihuana, Spanish terms for the Cannabis sativa plant, traditionally known in English as hemp. The Oxford English Dictionary notes that the “currency” of marijuana “increased greatly in the United States in the 1930s in the context of the debate over the use of the drug, the term being preferred as a more exotic alternative to the familiar words hemp and cannabis.”

    Most of the slang variations date to that period as well, including weed. In 1929, American Speech included it “Among the New Words” and defined it as “marijuana cigarette.” Three years later, the OED cites Chicago Defender as reporting, “The humble ‘reefer,’ ‘the weed,’ the marijuana, or what have you by way of a name for a doped cigarette has moved to Park Ave. from Harlem.” It doesn’t surprise me that the first author cited using the term in its currently popular manner (no the in front, referring to the drug in general rather than to a cigarette) was the master, Raymond Chandler: “They were looking for … a suitcase full of weed.” (The Little Sister, 1949.)

    For decades, weed lurked in the weeds, as it were. Google’s Ngram Viewer (showing relative frequency in American printed sources) gives a rough sense that it started making its move to prominence in the early 1990s:

    Screen Shot 2014-02-28 at 9.47.38 AM

    Ngram Viewer includes data only through 2008, but it appears the trend has continued and weed is now on top. In Google Books searches confined to 2013 publications, smoke marijuana pops up 69 times, smoke pot 94 times, and smoke weed 149 times. That is also the sense one gets from Urban Dictionary, whose users have been inspired to contribute 225 separate definitions for weed. The most popular one, with more than 39,000 “up” votes, was posted by “AYB” and is short and sweet: “God’s gift to the world. Brings peace when used wisely.” Although Urban Dictionary’s custom is to follow the definition with an example of the word used in a sentence, AYB was apparently too distracted to comply and gave the sentence, “Pass the blunt, dude.”

    Urban Dictionary also offers definitions for the weed derivatives weeda, Weedabis, Weedable, Weedache, WeedAcres, Weedacus, Weedafarian, Weedagasm, weedage, Weedaginity, Weedaholic, Weed aint no drug, weedajuana, Weed Album, Weedalicious, Weed and Feed, weed and pussy, Weed Angel, weed anthem, weedar, Weedarded, Weedarm, weedasaurous-rex, and Weed-ash.

    Consequently, it didn’t surprise me that the wrong-number text message recently left on my phone concluded: “And I have no weed.”

    Why the recent weed dominance? It seems clear to me that it’s a generational thing. In the 1990s, a new generation of users wanted to distance themselves from their parents’ dope or pot (the latter dates from 1930s and apparently originated in African-American slang). Weed was already in the lexicon, and provided a nice implicit variation on the hippie-ish grass.

    Plus, its funny. For some time, it has been generally understood that anything related to marijuana is or is potentially humorous. This is probably due to a combination of factors: the illicitness of the drug, the fact that stoned people sometimes giggle, the fact that their actions can be perceived as comical (viz., Cheech and Chong), the widespread sense that unlike, say, alcohol or heroin, weed is not ultimately harmful. In any case, I, for one, chuckle when confronted with the word weedar. Not to mention “the munchies.”

    Weed has not completely penetrated mainstream journalism. The slang term most often found there is pot, probably partly because it’s so useful in headlines. Just the other day, my local Philadelphia Inquirer had an article called “Pot an Election Issue?” that used marijuana eleven times, pot six (not including the headline), and cannabis and weed one time each.

    The New York Times is a bit more proper and allows weed in its news columns only in direct quotations, as in the Ronan Farrow case. Otherwise it sticks to marijuana, even in the face of extreme word repetition. A front-page article published on Thursday, “Pivotal Point Is Seen on Legalizing Marijuana,” uses marijuana 27 times (not including the headline) with the only variations being “the drug” and (once) “cannabis.”

    Times columnists follow different rules, of course. A couple of months ago, David Brooks published a column that took a dim view of marijuana legalization. It began:

    For a little while in my teenage years, my friends and I smoked marijuana. It was fun. I have some fond memories of us all being silly together. I think those moments of uninhibited frolic deepened our friendships.

    But then we all sort of moved away from it. I don’t remember any big group decision that we should give up weed. It just sort of petered out, and, before long, we were scarcely using it.
    One does not associate David Brooks with uninhibited frolic. He is actually sort of the anti-Seth Rogen, and if the two of them are both using weed, I predict Rogen will fairly quickly start using something else. Something else as a word, that is.

  124. I am taking two chocholate bars one for morning and for sleep. I am taking too, an oil for my Prostate Cancer. I would to know what his oil’s name and where it can purchased.

  125. Dennis
    Can you help me understand the significance of tumor marker testing? I wrote to you in February about my daughter (Stage IV mets to stomach lining/spine, hip) who is taking in 1 gram of the oil per day. The blood test her doctor uses to chart her tumor markers is a 15-3 and 27-29 (med terminology) The markers for 15-3 were 145.3 and for 27-29 were 191.2 on March 5. Today she received bad news that they have jumped to 163.7 and 249.1. If one believes these tests, it says that the THC/CBD rich oil is not touching the cancer and it is growing at an alarming rate. How accurate are these tumor marker tests and how much weight should she place on the increase while on the oil?

    • Rose – Thank you for asking this question, but I have no knowledge about tumor marker testing. Hopefully there will be someone here who can give a good answer. ~Dennis

  126. Dennis – My lovely wife is up to a gram a day and will be for the next 50 days or so on her healing journey. Now looking ahead I was wondering about maintenance doses. Do you more have opinions/experience with this issue. I’ve read that maintenance doses can be taken anywhere from once a week to once a month. What in your experience is effective? And what would be a proper dose for maintenance? Would your tolerance
    change so that taking a gram less often than everyday be difficult for a 50% THC oil or so? Could one use a CBD only oil for maintenance?
    That’s a lot of questions I know but thank you!

    • I take a maintenance dose about half the treatment amount, daily. I use this regimen because all the males in my family have died with prostate cancer. I don’t want it coming back. If I have it in my DNA, then I need to keep the maintenance dose high enough to keep it from coming back. ~Dennis

  127. Dennis, what was your dosage when you got on the actual oil for your second time when you had the metastatic lesions. So, your maintenance dose is now half of that?

    • I took two caps of oil for treatment, now one cap of oil for maintenance. It wasn’t lab analyzed so I don’t know the amount in grams. I don’t worry about grams anyhow, I just took as much as I could tolerate. And that worked just fine. ~Dennis

      • Quebec doctors can now prescribe cannabis

        Dr. Yves Robert and Dr. Charles Bernard of the Collège des médecins du Québec addresses the changes to Canada’s marijuana laws during a press conference in Montreal Tuesday April 1st 2014.

        Quebec doctors will now be able to prescribe medical marijuana — but only for patients enrolled in research studies and for the treatment of a limited number of medical conditions — under new guidelines unveiled Tuesday by the province’s College of Physicians.

        The Quebec medical guidelines are believed to be the first in Canada since new federal regulations on medical marijuana took effect on Tuesday.

        Until now, Quebec doctors did not have the right to prescribe cannabis, only to diagnose certain medical conditions and fill out a form that a patient could then use to apply for an authorization by Health Canada to possess, grow and consume marijuana.

        The authorizations for an estimated 40,000 medical marijuana users across the country were to have expired on Tuesday, but the Federal Court of Canada issued an injunction in March allowing patients to continue to grow their own supply for now. On Monday, the federal government announced it plans to fight that injunction.

        Under the revised federal regulations, Health Canada will no longer supply medical marijuana and individuals with medical conditions will no longer be permitted to grow pot. The Harper government intends to choose commercial producers to cultivate marijuana under “secure and sanitary conditions,” and to distribute it through the mail to patients.

        “This is a new responsibility that has been placed on our shoulders,” said Dr. Charles Bernard, president of the Quebec College of Physicians.

        “This is a manoeuvre (by the federal government) to diminish access to these products and to make doctors take the blame for this,” Bernard added. “We want to be clear to the public and to patients that we as physicians have always maintained the same principles regarding medical marijuana.”

        The College’s long-standing position, repeated Tuesday, is that “the use of cannabis for medical purposes is not a treatment that is recognized by the medical profession.”

        Dr. Yves Robert, secretary of the College, added that medical marijuana creates “a dependency” similar to tobacco, and that is something that concerns physicians.

        However, Bernard said, doctors can enrol patients in experimental treatments for research purposes, and the College has decided that marijuana can be prescribed in that sense. To that end, the College hopes to set up a partnership by this summer with the Canadian Consortium for the Investigation of Cannabinoids (headed by McGill University researchers), which would make it possible for doctors to prescribe marijuana.

        Adam Greenblatt, executive director of the Medical Cannabis Access Society, criticized the Quebec guidelines for imposing more restrictions than the old federal regulations.

        He noted that the under the new provincial guidelines, only the following conditions will be considered for a medical marijuana prescription: multiple sclerosis, spinal cord injury, spinal cord disease, cancer, AIDS or HIV infection, severe arthritis, epilepsy and palliative care.

        Those are considered Category 1 conditions under federal regulations. But Health Canada also allows for Category 2 conditions for people who suffer from painful symptoms that are not outlined in the first category.

        “For now, this is actually worse than the old program, because it cuts out a lot of patients who don’t fit into this first category that the College released,” Greenblatt said.

  128. Dennis, thanks for being available to answer our questions. We really appreciate your time. I would like to run this by you. I talked to someone yesterday who said a doctor had told her that it isn’t known whether cannabis oil behaves like chemo – where it can become ineffective over time. Do you think there is any worry about taking it too long? (This doctor is an oncologist who believes in the oil and uses it with his patients.)

    • Mavis – Cannabinoids are nothing like chemo. Cannabinoids are structurally like neurotransmitters, they are purely protective of the human immune and neurological systems. It is an anti-aging nutrient to take your whole life. ~Dennis

  129. Dennis, is there ever a time when one should take a break from the cannabis oi – just for a short time when one has cancer? I just watched a you tube video that suggests that with use over time that the receptors will pull back and not be available for the oil. This video is called -” Dr. Dustin Sulak – The Resensitization Process”.
    Would love to hear your thoughts on this.

    • Mavis – It’s not like we need a break from cannabis; but if you want to increase your sensitivity you can “reset your receptors.” If you stop (or reduce) the cannabis for a couple of days, the receptors will become more sensitive. ~Dennis

  130. Dennis, If you reset your receptors so they become more sensitive, does that mean you can cut back on the oil and you will still get the same protection for cancer? Is it true that you are not getting enough oil if you don’t have any psychoactive feeling?

    • Mavis – Cannabis will continue to kill cancer even after the reset. It just gets more efficient with more receptors awake. When you cut back, more receptors are formed. If you are taking THC oil and not feeling anything, probably not much healing going on. ~Dennis

      • More receptors are formed on the cancer cells if you “reset”? My wife is taking .5 gram at night and .25 gram twice during the day. So if her daytime sleepiness has largely
        subsided that is a bad sign?

  131. If more receptors are formed when cutting back, then it seems that one should take a break occasionally in order to get more receptors and have them more sensitive. Also, I would think that one could take less cannabis oil and still get the benefit as long as you are still getting the psychoactive feeling. That would certainly save cost wise!

  132. Hi Dennis, I wrote to you before about my brother who has bladder cancer. he has been on a raw diet for the past 5 months and he is doing 1 1/2 gm of canibous oil daily and ozone treatment. the medical doctors are narrow minded and do not believe in anything but drugs and removal. do you think 1 1/2 gm of the oil is enough daily? thanks for your comment. it is greatly appreciated.

    • Queen – 1.5gms would seem to be enough. However in my treatment I took as much as I could tolerate; then after building tolerance, up the dose again. Over and over again. ~Dennis

  133. Dennis. Once again let me first thank you for your selfless giving and dedication. This is Joshua again. Every time I come to your site I am always amazed at the number of folks who still have a hard time placing one of the most through internal cleansing treatments in the perspective that it deserves. Coffee enemas. The liver gallbladder flush for cleansing the lower bowels, and upper GI. It is one of the most important things you can do along with the regular coffee enemas that the Gerson treatment encourages.
    The Liver is the main healing organ of the body. Using enemas, and flushes thins out the bile ,and creates a dialysis effect that moves through the blood and lymph cleaning and also creating Glutathione S Transferese. This substance is really important in the body because it creates ATP’ This is the substance your body creates to hold energy. By increasing the amount of GST in your body you make it a stronger body . Your mitrochondria now have three to four times its energy producing capability. More energy, more healing power. Eating crappy, low nutritional foods and drinks
    takes away all the energy you are trying to create. Eat well.
    The last concept that I feel I dont hear enough from your bloggers
    is that of the absolutely necessary trick of not eating anything that is mass produced. The giant food industry puts more toxic , addictive additives in all their packaged foods. Aluminum cans are poisonous. Soda is sweet death waiting to put you down.
    After studying alternative methods of healing for the last 20 years of my life I can now clearly see the corerelation between alternative healing modalities sometimes failing not because of the potentcy
    of these medicines. (I also include ozone, oil Hoxey and organic juice and food. If you neglect any of these important considerations in following an (effective) alternative healing modality, what ever it happens to be. You automatically decrease its efficacy. Because as you kill the cancer , virus, bacteria, whatever the underlying weakening agents were that were eating you , turn into stronger, more toxic forms. Creating more inflammation, pain, and further impede the progress that you have painstakingly created. Jesus was one of the most misunderstood religious leaders of all time. One of my favorite things that he personally used to quote was . Your body is the temple of your spirit. Keep it clean, while you continue to clean up your diet, and you wont be wasting any time , you’ll be earning it. BE WELL,
    God bless you Dennis.


  134. Dennis – we all really appreciate your insight and expertise and your story is wonderfully uplifting. Here’s my question. I’m confused over the above conversation regarding resetting the receptors. Doesn’t stopping for a couple of days contradict the “keep metabolic pressure” on the cancer cells strategy.? And are you referring specifically to the receptors on the cancer sells? My wife is up to a gram a day with about 40 or so days to go. Her daytime sleepiness has largely subsided. Does that mean she should up her dose or go through a “reset”? Thank you so much!

    • Jonas – Yes, stopping does contradict “keep the pressure on.” I refer to the CB1 receptor on the cancer cell. No need to reset. Take as much as you can tolerate to kill the cancer as fast as possible. ~Dennis

  135. Stage 4 patients – please do not rely on this for anything more than pain control. Get second opinions and listen to the doctors. DOnt do this instead of treatment. more research is needed before any conclusions can be made.

    • “Get second opinions and listen to the doctors.” Doctors in the cancer industry know absolutely nothing about cannabis oil. They do however know a lot about keeping their mostly ineffective and dangerous treatments and the money train rolling. The cancer industry, which I’m guessing you may be a member of, has little interest in cures.

  136. A comment for oooo – Have you had a bad experience with the oil that makes you say not to rely on this oil for stage 4?

  137. Hi My uncle has Hepatitis C (spelling?) and now doctors found a tumor in his liver, we would like to try the oil and get him started on treatment. How can we get the oil we live in Mexico and would like to order it being not legal to produce it but no problem to import it. Thanks

  138. Please contact me I am interested to discuss this as I have prostrate cancer and a biopsy from. 2008
    Looking for more ways to treat now just waiting and taking herb psa90 which has reduced Psa but has also taken testosterone to zero
    I would like to try yours and drop 00 for six months to see where the pad goes

  139. I have a question Dennis – Does it make sense at all to acquire legal CBD drops or oil to supplement cannabis oil that is high in THC, say 50% or so, and low in CBD at 5% or so? Thanks again.

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